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View article: Correction: Porphyrin overdrive rewires cancer cell metabolism
Correction: Porphyrin overdrive rewires cancer cell metabolism Open
Cancer cells exhibit a metabolic phenotype termed “porphyrin overdrive,” characterized by dysregulated heme metabolic pathways for intermediate accumulation. This rewiring is cancer-essential and cancer-specific. Targeting this vulnerabili…
View article: Porphyrin overdrive rewires cancer cell metabolism
Porphyrin overdrive rewires cancer cell metabolism Open
All cancer cells reprogram metabolism to support aberrant growth. Here, we report that cancer cells employ and depend on imbalanced and dynamic heme metabolic pathways, to accumulate heme intermediates, that is, porphyrins. We coined this …
View article: Porphyrin overdrive rewires pan-cancer cell metabolism
Porphyrin overdrive rewires pan-cancer cell metabolism Open
Porphyrin overdrive rewires pan-cancer cell metabolism All cancer cells reprogram metabolism to support aberrant growth. Here, we report that cancer cells employ and depend on imbalanced and dynamic heme metabolic pathways for their oncoge…