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View article: Harnessing agro-industrial by-products for food protein production: Ex-ante process design for precision fermentation using Trichoderma reesei
Harnessing agro-industrial by-products for food protein production: Ex-ante process design for precision fermentation using Trichoderma reesei Open
Precision fermentation (PF) is an emerging biotechnology that uses genetically modified microorganisms to produce proteins, fats, biochemicals, and vitamins with high accuracy, mimicking traditional animal and plant sources. Filamentous fu…
View article: The displacement of the σ70 finger in initial transcription is highly heterogeneous and promoter-dependent
The displacement of the σ70 finger in initial transcription is highly heterogeneous and promoter-dependent Open
Most bacterial sigma factors (σ) contain a highly conserved structural module, the ‘σ-finger’, which forms a loop that protrudes towards the RNA polymerase active centre in the open complex and has been implicated in pre-organization of te…
View article: Nutrient-adequate diets with the lowest greenhouse gas emissions or price are the least acceptable—insights from dietary optimisation modelling using the iOTA model®
Nutrient-adequate diets with the lowest greenhouse gas emissions or price are the least acceptable—insights from dietary optimisation modelling using the iOTA model® Open
Over the past decade, there has been an increasing interest in the environmental sustainability of diets because food systems are responsible for a third of the anthropogenic greenhouse gas emissions (GHGE). However, less attention has bee…
View article: Perspective: Framework for Developing Prediction Equations for Estimating the Absorption and Bioavailability of Nutrients from Foods
Perspective: Framework for Developing Prediction Equations for Estimating the Absorption and Bioavailability of Nutrients from Foods Open
Current nutrient intake recommendations, nutritional assessments, and food labeling rely on estimated total nutrient content in foods and dietary supplements. However, the adequacy of nutrient intake depends not only on the total amount co…
View article: Strategies for Closing Global Nutrient Gaps: Enhancing Distribution and Supply
Strategies for Closing Global Nutrient Gaps: Enhancing Distribution and Supply Open
Although current estimates suggest that global food production is enough to meet nutritional needs, there are still significant challenges with equitable distribution (1) . Tackling these disparities is essential for achieving global nutri…
View article: Development of a national food system mathematical model for exploring future scenarios and impacts
Development of a national food system mathematical model for exploring future scenarios and impacts Open
Sustainability in Aotearoa New Zealand’s food system is essential for environmental health (taiao ora) and human well-being (tangata ora). However, achieving resilience in our food system faces significant cross-sector challenges, requirin…
View article: Shifting the focus from animal species to livestock production systems: an interactive tool for evaluating food contributions relative to environmental impacts
Shifting the focus from animal species to livestock production systems: an interactive tool for evaluating food contributions relative to environmental impacts Open
View article: Harnessing Agro-Industrial By-products for Food Protein Production: Ex-ante Process Design for Precision Fermentation using Trichoderma Reesei
Harnessing Agro-Industrial By-products for Food Protein Production: Ex-ante Process Design for Precision Fermentation using Trichoderma Reesei Open
View article: Analysis of global nutrient gaps and their potential to be closed through redistribution and increased supply
Analysis of global nutrient gaps and their potential to be closed through redistribution and increased supply Open
Global food systems are crucial for sustaining life on Earth. Although estimates suggest that the current production system can provide enough food and nutrients for everyone, equitable distribution remains challenging. Understanding globa…
View article: Modeling the feasibility of fermentation-produced protein at a globally relevant scale
Modeling the feasibility of fermentation-produced protein at a globally relevant scale Open
Introduction Fermentation-produced protein (FPP) is gaining global interest as a means of protein production with potentially lower cost and environmental footprint than conventionally-produced animal-sourced proteins. However, estimates o…
View article: Alternative protein-based foods must contribute to micronutrient adequacy
Alternative protein-based foods must contribute to micronutrient adequacy Open
Sustainable diets must consider health, economic, environmental, and social outcomes. The development and production of alternative protein foods should also make these considerations. We examined the nutritional role of these foods, with …
View article: Complex network analysis and health implications of nutrient trade
Complex network analysis and health implications of nutrient trade Open
Food trade plays a key role in global nutrition, but the essential nutrients within this trade are understudied. We investigated the global nutrient trade network from 1986 to 2020, examining the relationship with income level and health o…
View article: An Algorithm to Assess Calcium Bioavailability from Foods
An Algorithm to Assess Calcium Bioavailability from Foods Open
View article: Large-scale multidisciplinary design optimization of the NASA lift-plus-cruise concept using a novel aircraft design framework
Large-scale multidisciplinary design optimization of the NASA lift-plus-cruise concept using a novel aircraft design framework Open
The conceptual design of eVTOL aircraft is a high-dimensional optimization problem that involves large numbers of continuous design parameters. Therefore, eVTOL design method would benefit from numerical optimization algorithms capable of …
View article: Statistical Topology and the Random Interstellar Medium
Statistical Topology and the Random Interstellar Medium Open
We use topological methods to investigate the small-scale variation and local spatial characteristics of the interstellar medium (ISM) in three regions of the southern sky. We demonstrate that there are circumstances where topological meth…
View article: Estimating cropland requirements for global food system scenario modeling
Estimating cropland requirements for global food system scenario modeling Open
Introduction The production of plant crops is foundational to the global food system. With the need for this system to become more sustainable while feeding an increasing global population, tools to investigate future food system scenarios…
View article: The DELTA Model: Applying a Global Perspective to ‘Sustainable’ Individual Dietary Choices to Explore Their Practicality
The DELTA Model: Applying a Global Perspective to ‘Sustainable’ Individual Dietary Choices to Explore Their Practicality Open
As pressure rises in the fight to reduce global warming, increasing scrutiny is falling on food systems. A growing number of individuals are looking to optimise their own diets for the benefit of the environment. To gain a holistic underst…
View article: Achieving Sustainable Nutrient Adequacy Globally and Locally
Achieving Sustainable Nutrient Adequacy Globally and Locally Open
Our ability to effectively nourish an increasing global population is one of the key challenges facing humanity. The global food system is incredibly complex: it is the world's largest economic sector; it has multiple inputs and outputs; i…
View article: Mean fields and fluctuations in compressible magnetohydrodynamic flows
Mean fields and fluctuations in compressible magnetohydrodynamic flows Open
We apply Gaussian smoothing to obtain mean magnetic field, density, velocity,\nand magnetic and kinetic energy densities from our numerical model of the\ninterstellar medium, based on three-dimensional magnetohydrodynamic equations\nin a s…
View article: Modeling the Contribution of Meat to Global Nutrient Availability
Modeling the Contribution of Meat to Global Nutrient Availability Open
An increasing global population requires increasing food and nutrient availability. Meat is recognized as a nutrient dense food, particularly notable for its high-quality protein content, B vitamin and mineral content. However, it is not k…
View article: Modeling the Contribution of Milk to Global Nutrition
Modeling the Contribution of Milk to Global Nutrition Open
Nutrient-rich foods play a major role in countering the challenges of nourishing an increasing global population. Milk is a source of high-quality protein and bioavailable amino acids, several vitamins, and minerals such as calcium. We use…
View article: Animal and plant-sourced nutrition: complementary not competitive
Animal and plant-sourced nutrition: complementary not competitive Open
Debate on the sustainability of the global food system often compares the environmental, economic and health impacts of plant- and animal-sourced foods. This distinction can mask the considerable variation in impacts across and within thes…
View article: Rare missense variants in Tropomyosin‐4 (TPM4) are associated with platelet dysfunction, cytoskeletal defects, and excessive bleeding
Rare missense variants in Tropomyosin‐4 (TPM4) are associated with platelet dysfunction, cytoskeletal defects, and excessive bleeding Open
Genetic and functional TPM4 defects are reported making TPM4 a diagnostic grade tier 1 gene and highlights the importance of including TPM4 in diagnostic genetic screening for patients with significant bleeding and undiagnosed platelet dis…
View article: The DELTA Model: Understanding the Ability of the Global Food System to Deliver Nutrition
The DELTA Model: Understanding the Ability of the Global Food System to Deliver Nutrition Open
While the environmental, social and economic sustainability of the current global food system attracts increasing research, its ability to nourish the global population must be prioritised. Our objective was to produce a computational mode…
View article: Use of the DELTA Model to Understand the Food System and Global Nutrition
Use of the DELTA Model to Understand the Food System and Global Nutrition Open
View article: Statistical Topology and the Random Interstellar Medium
Statistical Topology and the Random Interstellar Medium Open
We use topological methods to investigate the small-scale variation and local spatial characteristics of the interstellar medium (ISM) in three regions of the southern sky. We demonstrate that there are circumstances where topological meth…
View article: Correction: <i>New score for assessing bleeding risk in patients with atrial fibrillation treated with NOACs</i>
Correction: <i>New score for assessing bleeding risk in patients with atrial fibrillation treated with NOACs</i> Open
[This corrects the article DOI: 10.1136/openhrt-2018-000931.].
View article: Correction: <i>Selective and marked decrease of complement receptor C5aR2 in human thoracic aortic aneurysms: a dysregulation with potential inflammatory effects</i>
Correction: <i>Selective and marked decrease of complement receptor C5aR2 in human thoracic aortic aneurysms: a dysregulation with potential inflammatory effects</i> Open
[This corrects the article DOI: 10.1136/openhrt-2019-001098.].
View article: An In-Depth Investigation of Faraday Depth Spectrum Using Synthetic Observations of Turbulent MHD Simulations
An In-Depth Investigation of Faraday Depth Spectrum Using Synthetic Observations of Turbulent MHD Simulations Open
In this paper, we present a detailed analysis of the Faraday depth (FD) spectrum and its clean components obtained through the application of the commonly used technique of Faraday rotation measure synthesis to analyze spectro-polarimetric…
View article: An In-depth Investigation of Faraday Depth Spectrum Using Synthetic\n Observations of Turbulent MHD Simulations
An In-depth Investigation of Faraday Depth Spectrum Using Synthetic\n Observations of Turbulent MHD Simulations Open
In this paper we present a detailed analysis of the Faraday depth (FD)\nspectrum and its clean components obtained through the application of the\ncommonly used technique of Faraday rotation measure synthesis to analyze\nspectro-polarimetr…