Andrew D. Hoffmann
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View article: Double-positive T cells form heterotypic clusters with circulating tumor cells to foster cancer metastasis
Double-positive T cells form heterotypic clusters with circulating tumor cells to foster cancer metastasis Open
The immune ecosystem is central to maintaining effective defensive responses. However, it remains largely understudied how immune cells in the peripheral blood interact with circulating tumor cells (CTCs) in metastasis. Here, blood analysi…
View article: Identification of immune signatures associated with both SARS-CoV-2 infection and lung transplantation
Identification of immune signatures associated with both SARS-CoV-2 infection and lung transplantation Open
Lung transplantation (lung-tx) offers the last life-saving option for patients with COVID-19-associated lung injury (CALI). We show that the RBD-specific antibodies are dramatically reduced in these CALI lung-tx patients despite a comparab…
View article: Rare Subset of T Cells Form Heterotypic Clusters with Circulating Tumor Cells to Foster Cancer Metastasis
Rare Subset of T Cells Form Heterotypic Clusters with Circulating Tumor Cells to Foster Cancer Metastasis Open
The immune ecosystem is central to maintaining effective defensive responses. However, how immune cells in the periphery blood interact with circulating tumor cells (CTCs) – seeds of metastasis - remains largely understudied. Here, our ana…
View article: Supplementary Excel S4 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Excel S4 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Excel S4 shows the list of SNA-pull down glycoproteins detected via glycoproteiomics analysis
View article: Supplementary Figures S1-S17 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Figures S1-S17 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Figure S1-S17 show the methods of CTC analysis and CTC-associated survival (S1); glycosylation profiles of patient CTCs (S2); phenotypic effects of neuraminidase treatment and CD44 depletion on tumor clustering and sialylatio…
View article: Supplementary Video S10 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Video S10 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Video S10 shows the clustering video of siCD97 transfected ST6KO cells presented in Fig.5E.
View article: Supplementary Video S2 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Video S2 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Video S2 shows the clustering video of SNA low cells presented in Fig.2A.
View article: Supplementary Video S3 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Video S3 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Video S3 shows the clustering video of ST6KO cells presented in Fig.2B.
View article: Supplementary Video S13 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Video S13 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Video S13 shows the clustering video of siPODXL transfected ST6KO cells presented in Fig.5E.
View article: Supplementary Video S6 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Video S6 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Video S6 shows the clustering video of PAX treated cells presented in Fig.2E.
View article: Supplementary Video S12 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Video S12 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Video S12 shows the clustering video of siICAM1 transfected ST6KO cells presented in Fig.5E.
View article: Supplementary Excel S4 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Excel S4 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Excel S4 shows the list of SNA-pull down glycoproteins detected via glycoproteiomics analysis
View article: Supplementary Excel S3 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Excel S3 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Excel S3 shows the results of RNA sequencing.
View article: Supplementary Video S17 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Video S17 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Video S17 shows the clustering video of siCD97 transfected ST6WT cells presented in Supplementary Fig.S14B.
View article: Supplementary Video S5 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Video S5 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Video S5 shows the clustering video of ST6WT cells presented in Fig.2B.
View article: Supplementary Video S19 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Video S19 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Video S19 shows the clustering video of siICAM1 transfected ST6WT cells presented in Supplementary Fig.S14B.
View article: Supplementary Excel S3 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Excel S3 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Excel S3 shows the results of RNA sequencing.
View article: Supplementary Video S16 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Video S16 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Video S16 shows the clustering video of siALCAM1 transfected ST6WT cells presented in Supplementary Fig.S14B.
View article: Supplementary Excel S1 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Excel S1 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Excel S1 shows CTC numbers of the patients analyzed by CellSearch.
View article: Supplementary Video S13 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Video S13 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Video S13 shows the clustering video of siPODXL transfected ST6KO cells presented in Fig.5E.
View article: Supplementary Tables S1-S2 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Tables S1-S2 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Table S1 shows clinical characteristics and multivariable Cox regression model analysis of patients. Supplementary Table S2 shows the clinical characteristics of patients with breast cancer.
View article: Supplementary Video S20 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Video S20 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Video S20 shows the clustering video of siPODXL transfected ST6WT cells presented in Supplementary Fig.S14B.
View article: Supplementary Video S14 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Video S14 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Video S14 shows the clustering video of scrRNA transfected ST6WT cells presented in Fig.5E.
View article: Supplementary Video S18 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Video S18 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Video S18 shows the clustering video of siECE1 transfected ST6WT cells presented in Supplementary Fig.S14B.
View article: Supplementary Video S1 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Video S1 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Video S1 shows the clustering video of SNA high cells presented in Fig.2A.
View article: Supplementary Excel S5 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Excel S5 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Excel S5 shows sialylopeptides of glycoproteins.
View article: Supplementary Video S6 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Video S6 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Video S6 shows the clustering video of PAX treated cells presented in Fig.2E.
View article: Supplementary Video S20 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Video S20 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Video S20 shows the clustering video of siPODXL transfected ST6WT cells presented in Supplementary Fig.S14B.
View article: Supplementary Video S9 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer
Supplementary Video S9 from Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer Open
Supplementary Video S9 shows the clustering video of siALCAM1 transfected ST6KO cells presented in Fig.5E.