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Racial, socioeconomic, and neighborhood characteristics in relation to COVID-19 severity of illness for adolescents and young adults Open

Ayaat Dahleh, Andrew J. Bean, Tricia J. Johnson · 2023

This study tests the hypotheses that insurance status, race and ethnicity, and neighborhood characteristics are associated with hospital admission and severe health outcomes (Intensive Care Unit [ICU] admission and oxygen assistance) for y…

Table S2 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 Open

Javier A. Figueroa, Lynette M. Phillips, Tal Shahar, Anwar Hossain, Joy Gumin , et al. · 2023

MSC-derived exosomes contain highly expressed and highly enriched miRNA.

Figure S1 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 Open

Javier A. Figueroa, Lynette M. Phillips, Tal Shahar, Anwar Hossain, Joy Gumin , et al. · 2023

Uptake of GA-hMSC-derived exosomes by GSCs.

Data from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 Open

Javier A. Figueroa, Lynette M. Phillips, Tal Shahar, Anwar Hossain, Joy Gumin , et al. · 2023

Tumor–stromal communications impact tumorigenesis in ways that are incompletely understood. Here, we show that glioma-associated human mesenchymal stem cells (GA-hMSC), a newly identified stromal component of glioblastoma, release exosomes…

Table S1 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 Open

Javier A. Figueroa, Lynette M. Phillips, Tal Shahar, Anwar Hossain, Joy Gumin , et al. · 2023

GA-hMSCs and GSCs exhibit stem cell-like characteristics.

Table S2 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 Open

Javier A. Figueroa, Lynette M. Phillips, Tal Shahar, Anwar Hossain, Joy Gumin , et al. · 2023

MSC-derived exosomes contain highly expressed and highly enriched miRNA.

Figure S1 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 Open

Javier A. Figueroa, Lynette M. Phillips, Tal Shahar, Anwar Hossain, Joy Gumin , et al. · 2023

Uptake of GA-hMSC-derived exosomes by GSCs.

Figure S3 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 Open

Javier A. Figueroa, Lynette M. Phillips, Tal Shahar, Anwar Hossain, Joy Gumin , et al. · 2023

GA-hMSC-derived exosomes do not contain growth factors or cytokines.

Figure S2 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 Open

Javier A. Figueroa, Lynette M. Phillips, Tal Shahar, Anwar Hossain, Joy Gumin , et al. · 2023

GA-hMSC-derived exosomes increase GSC proliferation and clonogenicity.

Figure S2 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 Open

Javier A. Figueroa, Lynette M. Phillips, Tal Shahar, Anwar Hossain, Joy Gumin , et al. · 2023

GA-hMSC-derived exosomes increase GSC proliferation and clonogenicity.

Data from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 Open

Javier A. Figueroa, Lynette M. Phillips, Tal Shahar, Anwar Hossain, Joy Gumin , et al. · 2023

Tumor–stromal communications impact tumorigenesis in ways that are incompletely understood. Here, we show that glioma-associated human mesenchymal stem cells (GA-hMSC), a newly identified stromal component of glioblastoma, release exosomes…

Table S3 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 Open

Javier A. Figueroa, Lynette M. Phillips, Tal Shahar, Anwar Hossain, Joy Gumin , et al. · 2023

MicroRNAs enriched in GA-MSC-derived exosomes down-regulate predicted gene targets in GSCs.

Table S3 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 Open

Javier A. Figueroa, Lynette M. Phillips, Tal Shahar, Anwar Hossain, Joy Gumin , et al. · 2023

MicroRNAs enriched in GA-MSC-derived exosomes down-regulate predicted gene targets in GSCs.

Figure S4 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 Open

Javier A. Figueroa, Lynette M. Phillips, Tal Shahar, Anwar Hossain, Joy Gumin , et al. · 2023

GA-hMSC-derived exosomes increase miRNA expression and impact miRNA target gene expression in GSCs.

Figure S3 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 Open

Javier A. Figueroa, Lynette M. Phillips, Tal Shahar, Anwar Hossain, Joy Gumin , et al. · 2023

GA-hMSC-derived exosomes do not contain growth factors or cytokines.

Table S1 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 Open

Javier A. Figueroa, Lynette M. Phillips, Tal Shahar, Anwar Hossain, Joy Gumin , et al. · 2023

GA-hMSCs and GSCs exhibit stem cell-like characteristics.

Figure S5 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 Open

Javier A. Figueroa, Lynette M. Phillips, Tal Shahar, Anwar Hossain, Joy Gumin , et al. · 2023

NCOR1 levels impact GSC proliferation.

Figure S5 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 Open

Javier A. Figueroa, Lynette M. Phillips, Tal Shahar, Anwar Hossain, Joy Gumin , et al. · 2023

NCOR1 levels impact GSC proliferation.

Figure S4 from Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 Open

Javier A. Figueroa, Lynette M. Phillips, Tal Shahar, Anwar Hossain, Joy Gumin , et al. · 2023

GA-hMSC-derived exosomes increase miRNA expression and impact miRNA target gene expression in GSCs.

The impact of holistic review on correlations between doctoral student outcomes, and GPA and GRE scores in the biomedical sciences Open

Taylor Walters, Antonio Abeyta, Andrew J. Bean, Marenda A. Wilson · 2022

Graduate admissions committees throughout the United States examine both quantitative and qualitative data from applicants to make admissions determinations. A number of recent studies have examined the ability of commonly used quantitativ…

Disruption of Endosomal Sorting in Schwann Cells Leads to Defective Myelination and Endosomal Abnormalities Observed in Charcot-Marie-Tooth Disease Open

John W. McLean, Julie A. Wilson, Tina Tian, Jennifer A. Watson, Mary VanHart , et al. · 2022

Endosomal sorting plays a fundamental role in directing neural development. By altering the temporal and spatial distribution of membrane receptors, endosomes regulate signaling pathways that control the differentiation and function of neu…

Endosomal trafficking of the EGFR mutant, EGFRvIII, results in exosomal secretion that triggers astrocyte reactivity Open

Kimiya Memarzadeh, Anthony Patrizz, Edward C. Koellhoffer, Monica Gireud, Andrew J. Bean · 2019

Background: The epidermal growth factor receptor (EGFR) variant three (EGFRvIII) mutation is linked with approximately one third of Glioblastoma Multiforme (GBM) tumors and is associated with poor patient prognosis. Persistent signaling du…

Low UBE4B expression increases sensitivity of chemoresistant neuroblastoma cells to EGFR and STAT5 inhibition Open

Kimiya Memarzadeh, David J. Savage, Andrew J. Bean · 2019

Neuroblastoma is the most common malignancy in infants. Overexpression of the epidermal growth factor receptor (EGFR) in neuroblastoma tumors underlies resistance to chemotherapeutics. UBE4B, an E3/E4 ubiquitin ligase involved in EGFR degr…

A Model for Holistic Review in Graduate Admissions That Decouples the GRE from Race, Ethnicity, and Gender Open

Marenda A. Wilson, Max A. Odem, Taylor Walters, Anthony L. DePass, Andrew J. Bean · 2019

Graduate schools around the United States are working to improve access to science, technology, engineering, and mathematics (STEM) in a manner that reflects local and national demographics. The admissions process has been the focus of exa…

Prospective Student Database: Technological Support for Assessing the Effectiveness of Graduate Recruitment Activities Open

Marenda A. Wilson, W. A. Turner, Anthony L. DePass, Andrew J. Bean · 2018

To the Editor: As many of the readers of CBE-Life Sciences Education know, academic institutions compete to attract a finite number of graduate students.Prospective students make highstakes decisions regarding graduate education, and educa…

Institutional Interventions That Remove Barriers to Recruit and Retain Diverse Biomedical PhD Students Open

Marenda A. Wilson, Anthony L. DePass, Andrew J. Bean · 2018

The faculty and student populations in academia are not representative of the diversity in the U.S. population. Thus, research institutions and funding agencies invest significant funds and effort into recruitment and retention programs th…

Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGS Open

Jennifer A. Watson, Bula J. Bhattacharyya, Jada H. Vaden, Julie A. Wilson, Mert Icyuz , et al. · 2015

Neurons are particularly vulnerable to perturbations in endo-lysosomal transport, as several neurological disorders are caused by a primary deficit in this pathway. In this report, we used positional cloning to show that the spontaneously …

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