Andrew Kaiser
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View article: Combining CSPG4-CAR and CD20-CCR for treatment of metastatic melanoma
Combining CSPG4-CAR and CD20-CCR for treatment of metastatic melanoma Open
The prognosis for patients with metastatic melanoma is poor and treatment options are limited. Genetically-engineered T cell therapy targeting chondroitin sulfate proteoglycan 4 (CSPG4), however, represents a promising treatment option, es…
View article: Movie S2 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Movie S2 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Ca2+ responses of Fluo-4-loaded CD20 CAR T cells introduced into a slice made from a Raji tumor
View article: Movie S5 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Movie S5 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
EGFR CAR T cells accumulate and stop at the periphery of BxPC3 tumor islets
View article: Legends for supplementary figures and Videos from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Legends for supplementary figures and Videos from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Legends for supplementary Figures and Videos
View article: Figure S4 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Figure S4 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Ca2+ responses of EGFR CAR T cells in human renal tumor slices positive for ICAM-1
View article: Movie S4 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Movie S4 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Ca2+ responses of Fura-2-loaded CD20 CAR T cells during their interaction with CD20-expressing BxPC3 tumor cells
View article: Movie S9 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Movie S9 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Ca2+ responses of Fluo-4-loaded EGFR CAR T cells in a vibratome section of a human renal tumor
View article: Data from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Data from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Adoptive transfer of T cells expressing chimeric antigen receptors (CAR) has shown remarkable clinical efficacy against advanced B-cell malignancies but not yet against solid tumors. Here, we used fluorescent imaging microscopy and ex vivo…
View article: Data from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Data from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Adoptive transfer of T cells expressing chimeric antigen receptors (CAR) has shown remarkable clinical efficacy against advanced B-cell malignancies but not yet against solid tumors. Here, we used fluorescent imaging microscopy and ex vivo…
View article: Movie S2 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Movie S2 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Ca2+ responses of Fluo-4-loaded CD20 CAR T cells introduced into a slice made from a Raji tumor
View article: Figure S3 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Figure S3 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
CAR T cell-induced ICAM-1 expression by tumor cells facilitates lymphocyte activation and entry into tumor islets
View article: Movie S6 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Movie S6 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Ca2+ responses of Fluo-4-loaded EGFR CAR T cells in a vibratome section of a BxPC3 tumor
View article: Movie S8 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Movie S8 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Distribution and migration and EGFR CAR T cells in a vibratome section of a human renal tumor
View article: Movie S1 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Movie S1 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Ca2+ responses of Fura-2-loaded CD20 CAR T cells during their interaction with Raji B cells.
View article: Movie S8 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Movie S8 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Distribution and migration and EGFR CAR T cells in a vibratome section of a human renal tumor
View article: Legends for supplementary figures and Videos from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Legends for supplementary figures and Videos from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Legends for supplementary Figures and Videos
View article: Movie S3 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Movie S3 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Ca2+ responses of Fura-2-loaded EGFR CAR T cells during their interaction with BxPC3 tumor cells
View article: Figure S2 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Figure S2 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
ICAM-1 expression is associated with elevated T cell infiltration in human tumors
View article: Movie S9 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Movie S9 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Ca2+ responses of Fluo-4-loaded EGFR CAR T cells in a vibratome section of a human renal tumor
View article: Movie S5 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Movie S5 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
EGFR CAR T cells accumulate and stop at the periphery of BxPC3 tumor islets
View article: Movie S6 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Movie S6 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Ca2+ responses of Fluo-4-loaded EGFR CAR T cells in a vibratome section of a BxPC3 tumor
View article: Figure S1 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Figure S1 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
CAR T cell responsiveness is dependent on the spatial orientation of carcinoma cells
View article: Supplementary Table 1 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Supplementary Table 1 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Antibodies used in MACSima
View article: Movie S1 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Movie S1 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Ca2+ responses of Fura-2-loaded CD20 CAR T cells during their interaction with Raji B cells.
View article: Figure S3 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Figure S3 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
CAR T cell-induced ICAM-1 expression by tumor cells facilitates lymphocyte activation and entry into tumor islets
View article: Movie S7 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Movie S7 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Distribution and migration and EGFR CAR T cells in a vibratome section of a human lung tumor
View article: Figure S1 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Figure S1 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
CAR T cell responsiveness is dependent on the spatial orientation of carcinoma cells
View article: Supplementary Table 1 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Supplementary Table 1 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Antibodies used in MACSima
View article: Figure S2 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Figure S2 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
ICAM-1 expression is associated with elevated T cell infiltration in human tumors
View article: Movie S3 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1
Movie S3 from CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1 Open
Ca2+ responses of Fura-2-loaded EGFR CAR T cells during their interaction with BxPC3 tumor cells