Explanipedia

Boosting the influenza vaccine schedule in children with cancer: a prospective open-label study Open

Sung Kai Chiu, Eliska Furlong, E. McKinnon, Annette Fox, Stephany Sánchez Ovando , et al. · 2025

VEXAS: A review of current understandings and emerging treatment strategies Open

Robert Holden, Yogeshraj Jeelal, Andrew McLean‐Tooke, Kylan Pathmanathan, David Nolan · 2025

VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) syndrome is a late-onset autoinflammatory disorder, typically affecting males, caused by somatic mutations in the X-linked gene UBA1 encoding the E1 ubiquitin-activating enzy…

RESILIENCE (Retrospective Linkage Study of Autoimmune Encephalitis): protocol for an Australian retrospective cohort study of outcomes in autoimmune encephalitis using data linkage techniques Open

Amy J. Halliday, Katrina A. Lambert, Christine Bundell, Andrew McLean‐Tooke, David Gillis , et al. · 2024

Introduction The autoimmune encephalitides (AE) are a heterogeneous group of neurological disorders with significant morbidity and healthcare costs. Despite advancements in understanding their pathophysiology, uncertainties persist regardi…

Anti-voltage gated potassium channel antibodies (VGKC) – an audit Open

Pia Fitzgerald, Joanne Ong, Christine Bundell, Andrew McLean‐Tooke · 2024

Intrapleural therapy for pleural infection from bronchopleural fistula in an adult with <span>hyper‐IgE</span> syndrome Open

Sam Faber, Andrew McLean‐Tooke, Yi Jin Kuok, Gary Lee · 2023

We presented the case of an adult patient with hyper‐IgE syndrome (HIES) who was admitted acutely with a large hydropneumothorax from lung consolidation, a bronchopleural fistula and pleural infection. He has had recurrent pulmonary and sk…

Modeling COVID-19 disease processes by remote elicitation of causal Bayesian networks from medical experts Open

Steven Mascaro, Yue Wu, Owen Woodberry, Erik Nyberg, Ross Pearson , et al. · 2023

Background COVID-19 is a new multi-organ disease causing considerable worldwide morbidity and mortality. While many recognized pathophysiological mechanisms are involved, their exact causal relationships remain opaque. Better understanding…

Adverse event reports of anaphylaxis after Comirnaty and Vaxzevria <span>COVID‐19</span> vaccinations, Western Australia, 22 February to 30 June 2021 Open

Alexander Shivarev, Anastasia Phillips, Sam Brophy‐Williams, Tim Ford, Peter Richmond , et al. · 2022

Within the first 4 months of the Western Australian COVID‐19 immunisation programme, 49 suspected anaphylaxis cases were reported to the vaccine safety surveillance system. Twelve reports met Brighton Collaboration case definition, corresp…

A Novel Targeted Amplicon Next-Generation Sequencing Gene Panel for the Diagnosis of Common Variable Immunodeficiency Has a High Diagnostic Yield Open

William Kermode, Dianne De Santis, Linh Truong, Erika Della Mina, Sam Salman , et al. · 2022

Cross With Caution: Antibiotic Cross-Reactivity and Co-Reactivity Patterns in Severe Cutaneous Adverse Reactions Open

Grace Thompson, Andrew McLean‐Tooke, Michaela Lucas · 2021

Current understanding of cross-reactivity in severe cutaneous adverse reactions to beta-lactam antibiotics is limited, thereby making recommendations for future prescribing difficult. The underlying immunopathogenesis of these reactions is…

Autoimmunity elicited by the chemokine response to adenovirus vector vaccines may underlie vaccine‐induced immune thrombotic thrombocytopaenia: a hypothesis Open

Andrew McLean‐Tooke, Michaela Lucas, Martyn A. French · 2021

Pulmonary granulomas in a patient with positive ANCA and history of tuberculosis: case report Open

Boon Chuen Wong, Elina Tan, Andrew McLean‐Tooke · 2020

AB1184 BURDEN OF DISEASE AND DIRECT HEALTH CARE COSTS FOR PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS IN WESTERN AUSTRALIA Open

Warren Raymond, Gilda Ngo, Milica Ognjenovic, I. Li, Poh Voon Cheah , et al. · 2020

Fibromuscular dysplasia presenting with a deep vein thrombosis Open

Danielle Lam, Shirley Jansen, Jonathan Tibballs, Andrew McLean‐Tooke · 2020

A 41-year-old male patient presented with isolated right lower limb swelling. An ultrasound scan showed right external iliac and femoral vein deep vein thrombosis due to extrinsic compression by an aneurysm of the right common iliac artery…

Biogeographical variation in specific IgE recognition of temperate and subtropical grass pollen allergens in allergic rhinitis patients Open

Thina Hareesh Kailaivasan, Victoria Timbrell, Graham O. Solley, William Smith, Andrew McLean‐Tooke , et al. · 2020

Objective Globally, grass pollens (GP) are major aeroallergen triggers of allergic rhinitis (AR) and asthma. However, patterns of allergic sensitisation to pollen of temperate (Pooideae: Lolium perenne ) and subtropical (Chloridoideae: Cyn…

Tracheobronchitis in ulcerative colitis: a case report of therapeutic response with infliximab and review of the literature Open

Lisa Horgan, Siobhain Mulrennan, Lloyd D’Orsogna, Andrew McLean‐Tooke · 2019

Idiopathic and immune‐related pulmonary fibrosis: diagnostic and therapeutic challenges Open

Andrew McLean‐Tooke, Irene Moore, Fiona Lake · 2019

Interstitial lung disease (ILD) encompasses a large group of pulmonary conditions sharing common clinical, radiological and histopathological features as a consequence of fibrosis of the lung interstitium. The majority of ILDs are idiopath…

Disease flares, damage accrual and survival in ANCA-associated vasculitis in Western Australia Open

Shereen Paramalingam, Warren Raymond, Chanakya Sharma, Gursharan Dogra, Andrew McLean‐Tooke , et al. · 2019

Background: ANCA-associated vasculitis (AAV) is a potentially life-threatening condition for which limited Australian data are available. We investigated the clinical and epidemiological outcomes of AAV in the last decade in a tertiary set…

CGR 10: RAPIDLY PROGRESSIVE INTERSTITIAL LUNG DISEASE ASSOCIATED WITH MDA‐5 ANTIBODIES Open

Brittany Stevenson, Nathan T. Harvey, Andrew McLean‐Tooke · 2018

Background: Mutations in the TMEM 173 gene underlie a type I interferon associated disease, STING associated vasculopathy with onset in infancy (SAVI).Patients suffer cutaneous vasculopathy and interstitial lung disease, but are not known …

P50: DEVELOPMENT OF NEW ASCIA SUBCUTANEOUS IMMUNOGLOBULIN (SCIG) RESOURCES Open

Ellen Bonagua, Brenda Cruz, Annmarie Pendleton, Karl B. McCann, Joe Bertolini , et al. · 2018

Methods: the first TAPID face to face meeting was held in 2014, the TAPID project membership has increased from 12 to over 90 members.Teleconferences are now held each month and face to face meetings have been held in Melbourne in 2017 (20…

R5: ANTIBIOTIC ALLERGY LABELS ARE ASSOCIATED WITH ADVERSE CLINICAL OUTCOMES IN CHILDREN Open

Michaela Lucas, Annabelle Arnold, Aine Sommerfield, Michelle Trevenen, Laure Braconnier , et al. · 2018

allergy labelling in children significantly impacts on their clinical care.

Long-term control of laryngeal plasma cell mucositis with systemic immunosuppression Open

James Triplett, Geoffrey Hee, Andrew McLean‐Tooke, Michaela Lucas · 2018

Plasma cell mucositis (PCM) is a rare non-neoplastic plasma cell proliferative disorder of the mucous membranes, which typically presents as soft tissue lesions involving oral, upper airway or genital mucosa. Laryngeal involvement resultin…

Sjögren Syndrome With Associated Lymphocytic Interstitial Pneumonia Successfully Treated With Tacrolimus and Abatacept as an Alternative to Rituximab Open

Grace Thompson, Andrew McLean‐Tooke, Jérémy Wrobel, Melanie Lavender, Michaela Lucas · 2018

P87: USE OF RITUXIMAB TO TREAT MOOREN’S ULCER Open

Nicola M. Benwell, Andrew McLean‐Tooke · 2017

Peripheral ulcerative keratitis (PUK) can be a secondary manifestation of systemic autoimmune diseases, most commonly Rheumatoid arthritis (RA) and Granulomatosis Polyangiitis GPA). PUK can precede systemic symptoms and its presence may he…

CGR 9: OUT ON A LIMB: AN UNUSUAL CASE OF VASCULITIS Open

Bojana Knežević, Andrew McLean‐Tooke · 2017

A 23-year-old international student from Hong Kong, presented to hospital with a six week history of spontaneous left lower limb pain and swelling. Her mobility had gradually declined to the point that she was wheelchair-dependent. The pat…

Undetectable Mannose Binding Lectin and Corticosteroids Increase Serious Infection Risk in Rheumatoid Arthritis Open

Graeme J. Carroll, Krista Makin, Maxine Garnsey, Max Bulsara, Bronwyn V. Carroll , et al. · 2017

Undetectable MBL and prednisolone confer a high risk for an SI. The use of biologic DMARDs did not confer substantial SI risk in this observational study. MBL deficiency is hitherto an unrecognized risk factor for an SI in RA.

THU0688 Disease flares, damage accrual and survival in anca-associated vasculitis Open

Shereen Paramalingam, Gursharan Dogra, Andrew McLean‐Tooke, Johannes C. Nossent · 2017

ASCIA‐P70: IS TESTING FOR AQP4 ANTIBODIES IN CSF AND SERUM MORE SENSITIVE THAN SERUM ALONE? Open

Christine Bundell, Dinusha Chandratilleke, S.M. Griffiths, Mark Goulding, Peter Hollingsworth , et al. · 2016

Neuromyelitis Optica (NMO) describes a spectrum of inflammatory disorders of the central nervous system characterised by optic neuritis and longitudinal extensive transverse myelitis. Antibodies against aquaporin 4 (AQP4) water channels ha…

ASCIA‐P44: ASSESSING THE UTILITY OF THE BASOPHIL ACTIVATION TEST FOR THE DIAGNOSIS OF SUSPECTED ANAESTHETIC OR ANTIBIOTIC ALLERGY IN A WESTERN AUSTRALIAN COHORT Open

Joel Kidman, Christine Bundell, P. H. M. Sadleir, Yogesh Jeelall, Elizabeth Fisher , et al. · 2016

There is a significant health and economic burden to individuals and the health system for those with a drug allergy label (DAL), as has been shown for antibiotic allergies. The majority of these patients are not allergic and will tolerate…

A Multicentre Cross-Sectional Survey of Allergic Sensitisation to Subtropical and Temperate Grass Pollens Open

Janet M. Davies, Graham O. Solley, William Smith, Andrew McLean‐Tooke, Sheryl van Nunen , et al. · 2015

Management and timing of aortic replacement for aneurysmal disease in a 25 year-old female with active Takayasu's Arteritis Open

Taylor M. Law, Louis Okiwelu, Andrew McLean‐Tooke, Prakash Joshi · 2015

Andrew McLean‐Tooke YOU? Author Swipe