Explanipedia

Multinational transfusion practices and outcomes in haematology patients admitted to the intensive care unit Open

L. Oomen, Jimmy Schenk, Sanne de Bruin, Merijn C. Reuland, Claudia van den Oord , et al. · 2025

Background and Objectives The number of critically ill patients with haematological conditions is increasing, yet transfusion practices in this population remain poorly defined. This study aimed to compare transfusion strategies in critica…

Global transfusion practices in septic patients in the intensive care unit: insights from the <span>InPUT</span> ‐study sub‐analysis Open

Vincent C Kurucz, Andrew W. J. Flint, Alexis Poole, Merijn C. Reuland, Claudia van den Oord , et al. · 2025

Background Transfusion practices among intensive care unit (ICU) patients with sepsis vary widely. While restrictive hemoglobin thresholds for red blood cell (RBC) transfusion are well studied, the indications and thresholds for platelet a…

Platelet Transfusion Practices in the ICU: A Prospective Multicenter Cohort Study Open

Stefan F. van Wonderen, Jorinde Raasveld, Andrew W. J. Flint, Jimmy Schenk, Claudia van den Oord , et al. · 2025

Objective: There is a lack of comprehensive international data regarding platelet transfusion practices in the ICU. This study aimed to evaluate the current occurrence rate of platelet transfusion in the ICU and provide an overview of plat…

Blood Transfusion Practices in Intensive Care: A Prospective Observational Binational Study Open

Andrew W. J. Flint, Alexis Poole, Jorinde Raasveld, Michael Bailey, K. Brady , et al. · 2025

IMPORTANCE: Blood transfusions are a common and potentially lifesaving intervention in ICU patients but are associated with harm and often transfused inconsistently with guidelines. However, it is not well known how ICU transfusion practic…

Plasma transfusion in the intensive care unit Open

Maite M.T. van Haeren, Jorinde Raasveld, Sanne de Bruin, Merijn C. Reuland, Claudia van den Oord , et al. · 2024

Background Current guidelines discourage prophylactic plasma use in non‐bleeding patients. This study assesses global plasma transfusion practices in the intensive care unit (ICU) and their alignment with current guidelines. Study Design a…

Transfusion practices in intensive care units: An Australian and New Zealand point prevalence study Open

Andrew W. J. Flint, K. Brady, Erica M. Wood, Lê Thị Phương Thảo, Naomi Hammond , et al. · 2023

Non-RBC transfusion decisions are often not aligned with guidelines and VHA is commonly available but rarely used to guide transfusions. Better evidence to guide transfusions in ICUs is needed.

Red Blood Cell Transfusion in the Intensive Care Unit Open

Jorinde Raasveld, Sanne de Bruin, Merijn C. Reuland, Claudia van den Oord, Jimmy Schenk , et al. · 2023

Importance Red blood cell (RBC) transfusion is common among patients admitted to the intensive care unit (ICU). Despite multiple randomized clinical trials of hemoglobin (Hb) thresholds for transfusion, little is known about how these thre…

Preoperative identification of cardiac surgery patients at risk of receiving a platelet transfusion: The Australian Cardiac Surgery Platelet Transfusion (<span>ACSePT</span>) risk prediction tool Open

Andrew W. J. Flint, Michael Bailey, Christopher M. Reid, Julian A. Smith, Lavinia Tran , et al. · 2020

Background Platelet (PLT) transfusions are limited and costly resources. Accurately predicting clinical demand while limiting product wastage remains difficult. A PLT transfusion prediction score was developed for use in cardiac surgery pa…

Is Platelet Expiring Out of Date? A Systematic Review Open

Andrew W. J. Flint, Zoe McQuilten, Gregory Irwin, Kylie Rushford, Helen E Haysom , et al. · 2019

Platelet storage duration and its clinical and transfusion outcomes: a systematic review Open

Cécile Aubron, Andrew W. J. Flint, Yves Ozier, Zoe McQuilten · 2018

Duration of platelet storage and outcomes of critically ill patients Open

Andrew W. J. Flint, Cécile Aubron, Michael Bailey, Rinaldo Bellomo, David Pilcher , et al. · 2017

BACKGROUND The storage duration of platelet (PLT) units is limited to 5 to 7 days. This study investigates whether PLT storage duration is associated with patient outcomes in critically ill patients. STUDY DESIGN AND METHODS This study was…

Is platelet transfusion associated with hospital-acquired infections in critically ill patients? Open

Cécile Aubron, Andrew W. J. Flint, Michael Bailey, David Pilcher, Allen Cheng , et al. · 2017

Transfusion of stored platelets: balancing risks and product availability Open

Cécile Aubron, Andrew W. J. Flint, Yves Ozier, Zoe McQuilten · 2016

Platelet (PLT) transfusions are used for both treatment of bleeding and preventing bleeding in patients with thrombocytopenia and/or functionally abnormal PLTs. To ensure the efficacy of transfused PLTs, they must be stored at room tempera…

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