Explanipedia

Development of right ventricular electromechanical dyssynchrony following surgical repair of tetralogy of Fallot in infants Open

Andrew W. McCrary, Sydney D. Collins, Zebulon Z. Spector, P. Andrea Kropf, Piers Barker , et al. · 2025

Background In adolescents and adults with tetralogy of Fallot (TOF), right ventricle (RV) electromechanical dyssynchrony (EMD) due to right bundle branch block (RBBB) is associated with reduced exercise capacity and RV dysfunction. While t…

Making it work for all: equity in single ventricle monitoring Open

Meredith Sooy-Mossey, Sarah Tallent, Christoph P. Hornik, S.A. Park, Anne C. Schmelzer , et al. · 2024

Background: Interstage monitoring programs for single ventricle disease have been developed to reduce morbidity and mortality. There is increased use of telemedicine and mobile application monitoring. It is unknown if there are disparities…

Proteomics discovery in children and young adults with HIV identifies fibrosis, inflammatory, and immune biomarkers associated with myocardial impairment Open

Josephine Harrington, Andrew W. McCrary, Maggie Nguyen, Winstone Nyandiko, Piers Barker , et al. · 2024

People with HIV are at increased risk of cardiac dysfunction; however, limited tools are available to identify patients at highest risk for future cardiac disease. We performed proteomic profiling using plasma samples from children and you…

Detection of occult thrombosis in individuals with Fontan circulation by cardiac MRI Open

Samantha F. Curtis, Mariah Cicioni, Alexandria Mullikin, Jason Williams, Jeffrey M. Campbell , et al. · 2024

Objective: Identifying thrombus formation in Fontan circulation has been highly variable, with reports between 17 and 33%. Initially, thrombus detection was mainly done through echocardiograms. Delayed-enhancement cardiac MRI is emerging a…

Diffuse myocardial fibrosis is uncommon in people with perinatally acquired human immunodeficiency virus infection Open

Jason Williams, Frances Hung, Elizabeth Jenista, Piers Barker, Hrishikesh Chakraborty , et al. · 2024

Background Cardiovascular disease (CVD) remains a leading cause of death in people living with HIV. Myocardial fibrosis is well-described in HIV infection acquired in adulthood. We evaluate the burden of fibrosis by cardiac magnetic resona…

Letter to the Editor: Cardiac Dysfunction Among Youth With Perinatal HIV Acquisition and Exposure Open

Andrew W. McCrary, Frances Hung, Michael Foster, Myra Koech, Joan Nekesa , et al. · 2024

McCrary, Andrew W. MD, MSc; Hung, Frances MS; Foster, Michael C. BA, RSC, RCCS, RDCS; Koech, Myra MBChB, MMed; Nekesa, Joan BS; Thielman, Nathan MD; Chakraborty, Hrishikesh DrPH; Bloomfield, Gerald S. MD, MPH; Nyandiko, Winstone MBChB, MMe…

Staged repair of borderline hypoplastic heart disease with early biventricular conversion Open

Nicholas D. Andersen, Douglas M. Overbey, Neel K. Prabhu, Andrew W. McCrary, Jennifer Sherwin , et al. · 2024

Dark Blood Delayed Enhancement Improves Diagnostic Accuracy in Patients Post-surgical Correction for D-transposition of the Great Arteries Open

Jason Williams, Piers Barker, Sydney Collins, Andrew W. McCrary, Michael J. Campbell · 2024

Development and Temporal Validation of a Machine Learning Model to Predict Clinical Deterioration Open

Henry P. Foote, Zohaib Shaikh, Daniel M. Witt, Tong Shen, William Ratliff , et al. · 2023

OBJECTIVES Early warning scores detecting clinical deterioration in pediatric inpatients have wide-ranging performance and use a limited number of clinical features. This study developed a machine learning model leveraging multiple static …

Diffuse Myocardial Fibrosis is Uncommon in People with Perinatally Acquired Human Immunodeficiency Virus Infection Open

Jason Williams, Frances Hung, Elizabeth Jenista, Piers Barker, Hrishikesh Chakraborty , et al. · 2023

Background Cardiovascular disease (CVD) remains a leading cause of death in people living with HIV. Myocardial fibrosis is well-described in HIV infection acquired in adulthood. We evaluate the burden of fibrosis by cardiac magnetic resona…

Center-level factors associated with shorter length of stay following stage 1 palliation: An analysis of the national pediatric cardiology quality improvement collaborative registry Open

Henry P. Foote, Dylan Thibault, Carla Dominguez Gonzalez, Garick D. Hill, L. LuAnn Minich , et al. · 2023

Risk of in-hospital Deterioration for Children with Single Ventricle Physiology Open

Henry P. Foote, Grace S. Lee, Carla Dominguez Gonzalez, Zohaib Shaik, William Ratliff , et al. · 2023

Risk of in-hospital deterioration for children with single ventricle physiology Open

Henry P. Foote, Grace S. Lee, Carla Dominguez Gonzalez, Zohaib Shaikh, William Ratliff , et al. · 2023

Children with single ventricle physiology (SV) are at high risk of in-hospital morbidity and mortality. Identifying children at risk for deterioration may allow for earlier escalation of care and subsequently decreased mortality. We conduc…

Impact of Udenafil on Echocardiographic Indices of Single Ventricle Size and Function in FUEL Study Participants Open

Michael V. Di Maria, David Goldberg, Victor Zak, Chenwei Hu, Adam M. Lubert , et al. · 2022

Background: The FUEL trial (Fontan Udenafil Exercise Longitudinal) demonstrated statistical improvements in exercise capacity following 6 months of treatment with udenafil (87.5 mg po BID). The effect of udenafil on echocardiographic measu…

Tricuspid regurgitation and left ventricular eccentricity as a measure of heart failure in the newborn patient with a vein of Galen malformation: illustrative case Open

Jeremy A. Yarden, Lily I. Hauck, Kamlesh V. Athavale, Andrew W. McCrary, Michael J. Campbell , et al. · 2022

BACKGROUND Successful management of a vein of Galen malformation (VoGM) in the newborn patient requires a highly coordinated team approach involving neonatologists, pediatric cardiologists, pediatric neurologists, neurosurgeons, and interv…

Postoperative Renal Failure, Shunt Type, and Mortality After Norwood Palliation Open

Reid C. Chamberlain, Nicholas D. Andersen, Andrew W. McCrary, Christoph P. Hornik, Kevin D. Hill · 2021

Early cardiac dysfunction in children and young adults with perinatally acquired HIV Open

Andrew W. McCrary, Winstone Nyandiko, Alicia M. Ellis, Hrishikesh Chakraborty, Michael J. Muehlbauer , et al. · 2019

Objective: To define the prevalence of early cardiac dysfunction in children and young adults with perinatally acquired HIV and predictors of cardiac function. Design: Cross-sectional design. Methods: Early cardiac dysfunction was defined …

Agreement of an echocardiogram-based diagnosis of pulmonary hypertension in infants at risk for bronchopulmonary dysplasia among masked reviewers Open

Andrew W. McCrary, Piers Barker, Rachel D. Török, Tracy Spears, Jennifer S. Li , et al. · 2018

Case 3: Respiratory Distress and Tachycardia in a Preterm Neonate Open

Andrew W. McCrary, Laura Page, Gregory H. Tatum, Rachel G. Greenberg, Stephanie Burns Wechsler , et al. · 2017

A 31-week-gestation male infant is delivered vaginally in the setting of preterm labor and chorioamnionitis. The pregnancy was remarkable for late prenatal care, but no other complications. Maternal antenatal testing results were normal an…

Differences in Eccentricity Index and Systolic–Diastolic Ratio in Extremely Low-Birth-Weight Infants with Bronchopulmonary Dysplasia at Risk of Pulmonary Hypertension Open

Andrew W. McCrary, Jonathan R. Malowitz, Conrad A. Hornick, Kevin D. Hill, C. Cotten , et al. · 2015

The EI and SD ratio may be useful as a screening tool for PH in this population.

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