Explanipedia

Digital smartphone versus analogue methods of measuring orbital implant motility after enucleation Open

Bhavesh P. Gopal, Stephen T. Bell, Noha M Soliman, David Sia, Andrew W. Stacey , et al. · 2025

Purpose To compare standard rule measurement (gold standard, analogue) method of orbital implant motility against digital image analysis on smart phone measurement software, Medigrid and ImageJ. Design Single centre observational, non-rand…

Simultaneous conjunctival melanomas in one eye treated with both adjuvant brachytherapy and proton beam radiotherapy Open

Laura D. Selby, Kent Wallner, Evan Hall, Nina A. Mayr, Alexei V. Chvetsov , et al. · 2025

Synchronized long-read genome, methylome, epigenome and transcriptome profiling resolve a Mendelian condition Open

Mitchell R. Vollger, Jonas Korlach, Kiara C. Eldred, Elliott Swanson, Jason G. Underwood , et al. · 2025

Prognostic importance of direct assignment of parent of origin via long-read genome and epigenome sequencing in retinoblastoma Open

Andrew W. Stacey, Kazuo Nakamichi, Jennifer Huey, Jeffrey Stevens, Natalie Waligorski , et al. · 2024

BACKGROUNDCurrent clinical sequencing methods cannot effectively detect DNA methylation and allele-specific variation to provide parent-of-origin information from the proband alone. Parent-of-origin effects can lead to differential disease…

Retinoblastoma survival and enucleation outcomes in 41 countries from the African continent Open

Thamanna Nishath, Andrew W. Stacey, David Steinberg, Allen Foster, Richard Bowman , et al. · 2024

Background Retinoblastoma is the most common intraocular malignancy in childhood. Despite one-third of cases occurring in Africa, little is known of the outcomes on the continent. This study aims to explore survival and globe salvage outco…

B7-H3 Expression in Breast Cancer and Brain Metastasis Open

Vaibhavi Joshi, Kate Beecher, Malcolm Lim, Andrew W. Stacey, Yufan Feng , et al. · 2024

Brain metastasis is a significant challenge for some breast cancer patients, marked by its aggressive nature, limited treatment options, and poor clinical outcomes. Immunotherapies have emerged as a promising avenue for brain metastasis tr…

Utilization of fundus image for target delineation and contouring for treatment of ocular melanoma Open

Alice Fung, Lia M. Halasz, Andrew W. Stacey, John J. Chen, Jitender Saini · 2024

<span>NDRG1</span> is a prognostic biomarker in breast cancer and breast cancer brain metastasis Open

Vaibhavi Joshi, Andrew W. Stacey, Yufan Feng, Priyakshi Kalita‐de Croft, Pascal H. G. Duijf , et al. · 2024

Brain metastases are secondary brain tumours characterised by their aggressive nature and poor prognosis. Breast cancer is one of the most common primary tumours in women to spread to the brain. A lack of biomarkers predicting likely sprea…

Successful Treatment Response of a Juxtapapillary Retinal Capillary Hemangioblastoma Due to von Hippel–Lindau Syndrome with Belzutifan in a Pediatric Patient Open

Debarshi Mustafi, Johnson Huang, Michelle Ting, Natalie Waligorski, Andrew W. Stacey , et al. · 2023

Mustafi, Debarshi MD, PHD; Huang, Johnson MD; Ting, Michelle A. MD; Waligorski, Natalie MS; Stacey, Andrew W. MD; Huang, Laura C. MD Author Information

A Multicenter Analysis of Nucleic Acid Quantification Using Aqueous Humor Liquid Biopsy in Retinoblastoma Open

Deborah Im, Sarah Pike, Mark W. Reid, Chen‐Ching Peng, Shreya Sirivolu , et al. · 2023

Proprietary or commercial disclosure may be found after the references.

Does the Current Global Health Agenda Lack Vision? Open

Sam L. Forrest, Carmel L. Mercado, Cyril Engmann, Andrew W. Stacey, Luxme Hariharan , et al. · 2023

Given increasing rates of visual impairment worldwide, we call on national health plans and global development agencies to urgently focus funding and resources toward vision and eye health, with an emphasis on data collection surrounding n…

Stability of a Simple Bioreactor Model with a General Growth Function, Bacterial Feed and Death Rate Open

Andrew W. Stacey, John Shepherd · 2022

Biological reactors are employed in industrial applications to break down organic waste. Here we consider the stability of an open loop CSTR, with a general growth rate function, having both a bacterial and substrate feed and a death rate.…

Risk factors associated with abandonment of care in retinoblastoma: analysis of 692 patients from 10 countries Open

Thamanna Nishath, Xiudi Li, Arthika Chandramohan, Megan Othus, Xunda Ji , et al. · 2022

Background Rates of care abandonment for retinoblastoma (RB) demonstrate significant geographical variation; however, other variables that place a patient at risk of abandoning care remain unclear. This study aims to identify the risk fact…

Identification of Metastatic Conjunctival Squamous Cell Carcinoma through Neck Palpation Open

Thamanna Nishath, Minh T. Nguyen, Michael C. Wu, Desiree A. Marshall, Andrew W. Stacey · 2022

An 80-year-old male with a distant 10 pack-years smoking history and squamous cell carcinoma (SCCA) of the scalp diagnosed 15 years ago presented with a new right nasal bulbar conjunctival lesion found to be invasive SCCA. The patient was …

PHOTODYNAMIC THERAPY FOR THE TREATMENT OF CHOROIDAL METASTASES: A Case Series and Meta-analysis. Open

Minh T. Nguyen, Andrew W. Stacey · 2022

Photodynamic therapy is effective at controlling tumors and preserving vision in patients with some choroidal metastases. Because of its minimal time commitment and good safety profile, PDT should be considered as a potential first-line tr…

The role of maternal age & birth order on the development of unilateral and bilateral retinoblastoma: a multicentre study Open

Philippa Lloyd, Mark Westcott, Swathi Kaliki, Xunda Ji, Yihua Zou , et al. · 2022

Background/Objectives Retinoblastoma is a common childhood intraocular malignancy, the bilateral form of which most commonly results from a de novo germline pathogenic variant in the RB1 gene. Both advanced maternal age and decreasing birt…

Unilateral peripheral vascular retinal disease associated with a developmental arcade vessel anomaly in adult-onset Coats’ disease Open

Debarshi Mustafi, Andrew W. Stacey · 2022

Uveal melanoma incidentally diagnosed with neuroimaging, a case series of 3 patients Open

Mai Tsukikawa, Babatunde Akinpelu, Pattana Wangaryattawanich, Kathryn P. Scherpelz, Andrew W. Stacey · 2021

Improved Prognostic Precision in Uveal Melanoma through a Combined Score of Clinical Stage and Molecular Prognostication Open

Andrew W. Stacey, Vaidehi S. Dedania, Miguel A. Materin, Hakan Demirci · 2021

Introduction: Prognosis of uveal melanoma (UM) is assessed using clinical staging or molecular testing. Two modalities often used for prognostication are the American Joint Committee on Cancer (AJCC) staging and a tumor gene …

The Effects of Breastfeeding on Retinoblastoma Development: Results from an International Multicenter Retinoblastoma Survey Open

Jasmeen Randhawa, Mary E. Kim, Ashley Polski, Mark W. Reid, Kristen Mascarenhas , et al. · 2021

The protective effects of breastfeeding on various childhood malignancies have been established but an association has not yet been determined for retinoblastoma (RB). We aimed to further investigate the role of breastfeeding in the severi…

Hemorrhagic choroidal detachment as the presenting sign of uveal melanoma Open

Yewlin E. Chee, Raghu C. Mudumbai, Steven S. Saraf, Thellea K. Leveque, Verena S. Grieco , et al. · 2021

Sex, gender, and retinoblastoma: analysis of 4351 patients from 153 countries Open

Ido Didi Fabian, Vikas Khetan, Andrew W. Stacey, Allen Foster, Dupe Ademola-Popoola , et al. · 2021

The Effects of Breastfeeding on Retinoblastoma Development Open

Jasmeen Randhawa, Mary E. Kim, Ashley Polski, Mark W. Reid, Brianne Brown , et al. · 2021

Lag Time between Onset of First Symptom and Treatment of Retinoblastoma: An International Collaborative Study of 692 Patients from 10 Countries Open

Swathi Kaliki, Xunda Ji, Yihua Zou, Riffat Rashid, Sadia Sultana , et al. · 2021

Background: The relationship between lag time and outcomes in retinoblastoma (RB) is unclear. In this study, we aimed to study the effect of lag time between onset of symptoms and diagnosis of retinoblastoma (RB) in countries based on thei…

Incidence of Retinoblastoma Has Increased: Results from 40 European Countries Open

Andrew W. Stacey, Richard Bowman, Allen Foster, Tero Kivelä, Francis L. Munier , et al. · 2021

International travel to obtain medical treatment for primary retinoblastoma: A global cohort study Open

Richard Bowman, Allen Foster, Andrew W. Stacey, Naama Keren‐Froim, Cova Bascaran , et al. · 2020

Early diagnosis and treatment of retinoblastoma (Rb), the most common intraocular malignancy, can save both the child's life and vision. However, access to services and hence chances for survival and preserving the eye and its vision vary …

Progressive Preretinal Fibrosis with Late, Ossifying, Proliferative Retinopathy following Treatment for Retinoblastoma Open

Minh T. Nguyen, Jessica Saunders, María Pacheco, Andrew W. Stacey · 2020

We report a case of retinal atrophy and progressive preretinal fibrosis in an eye previously treated with intravenous and intra-arterial chemotherapy (IAC), which evolved immediately after treatment with intravitreal injection of melphalan…

Travel burden and clinical presentation of retinoblastoma: analysis of 1024 patients from 43 African countries and 518 patients from 40 European countries Open

Ido Didi Fabian, Andrew W. Stacey, Allen Foster, Tero Kivelä, Francis L. Munier , et al. · 2020

Background The travel distance from home to a treatment centre, which may impact the stage at diagnosis, has not been investigated for retinoblastoma, the most common childhood eye cancer. We aimed to investigate the travel burden and its …

Retinoblastoma management during the COVID‐19 pandemic: A report by the Global Retinoblastoma Study Group including 194 centers from 94 countries Open

Ido Didi Fabian, Andrew W. Stacey, Richard Bowman, Vikas Khetan, Sharon Blum , et al. · 2020

We declare no competing interests relevant to the present work. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) …

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