Andrianna I. Ayiotis
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View article: Patient-Reported Outcomes After Vestibular Implantation for Bilateral Vestibular Hypofunction
Patient-Reported Outcomes After Vestibular Implantation for Bilateral Vestibular Hypofunction Open
Importance Standard-of-care treatment proves inadequate for many patients with bilateral vestibular hypofunction (BVH). Vestibular implantation is an emerging alternative. Objective To examine patient-reported outcomes from prosthetic vest…
View article: VESTIBULAR IMPLANT STIMULATION PAUSE DETECTION THRESHOLDS: IMPLICATIONS FOR DESIGN OF BATTERY DEPLETION ALERTS
VESTIBULAR IMPLANT STIMULATION PAUSE DETECTION THRESHOLDS: IMPLICATIONS FOR DESIGN OF BATTERY DEPLETION ALERTS Open
Vestibular implants (VI) modulate the rate and amplitude of charge-balanced current pulses to encode head angular velocity or acceleration. When the battery of a VI becomes depleted, stimulation interruptions can cause vertigo. To avoid th…
View article: Binocular 3-D otolith-ocular reflexes: responses of chinchillas to natural and prosthetic stimulation after ototoxic injury and vestibular implantation
Binocular 3-D otolith-ocular reflexes: responses of chinchillas to natural and prosthetic stimulation after ototoxic injury and vestibular implantation Open
Previous studies to expand the scope of prosthetic stimulation of the otolith end organs showed that selective stimulation of the utricle and saccule is possible. This article further defines those possibilities by characterizing a disease…
View article: Vestibular Implantation Can Work Even After More Than 20 Years of Bilateral Vestibular Hypofunction
Vestibular Implantation Can Work Even After More Than 20 Years of Bilateral Vestibular Hypofunction Open
Objective To determine whether prosthetic stimulation delivered via a vestibular implant can elicit artificial sensation of head movement despite long (23-yr) duration adult-onset ototoxic bilateral vestibular hypofunction (BVH). Study Des…
View article: Development and Content Validity of the Bilateral Vestibulopathy Questionnaire
Development and Content Validity of the Bilateral Vestibulopathy Questionnaire Open
Background To date, the burden and severity of the full spectrum of bilateral vestibulopathy (BVP) symptoms has not yet been measured in a standardized manner. Since therapeutic interventions aiming to improve BVP symptoms are emerging, th…
View article: Posture, Gait, Quality of Life, and Hearing with a Vestibular Implant
Posture, Gait, Quality of Life, and Hearing with a Vestibular Implant Open
Six months and 1 year after unilateral implantation of a vestibular prosthesis for bilateral vestibular hypofunction, measures of posture, gait, and quality of life were generally in the direction of improvement from baseline, but hearing …
View article: Retinoic acid degradation shapes zonal development of vestibular organs and sensitivity to transient linear accelerations
Retinoic acid degradation shapes zonal development of vestibular organs and sensitivity to transient linear accelerations Open
Each vestibular sensory epithelium in the inner ear is divided morphologically and physiologically into two zones, called the striola and extrastriola in otolith organ maculae, and the central and peripheral zones in semicircular canal cri…
View article: Continuous vestibular implant stimulation partially restores eye-stabilizing reflexes
Continuous vestibular implant stimulation partially restores eye-stabilizing reflexes Open
BACKGROUNDBilateral loss of vestibular (inner ear inertial) sensation causes chronically blurred vision during head movement, postural instability, and increased fall risk. Individuals who fail to compensate despite rehabilitation therapy …
View article: Cytochrome P450 26b1-mediated specification of vestibular striola and central zones is required for transient responses in linear acceleration
Cytochrome P450 26b1-mediated specification of vestibular striola and central zones is required for transient responses in linear acceleration Open
Each vestibular sensory epithelia of the inner ear is divided into two zones, the striola and extrastriola in maculae of otolith organs and the central and peripheral zones in cristae of semicircular canals, that differ in morphology and p…