Andriy Myronovych
YOU?
Author Swipe
View article: The evolution of steatosis and fibrosis in mice on a MASH-inducing diet and the effects of housing temperature
The evolution of steatosis and fibrosis in mice on a MASH-inducing diet and the effects of housing temperature Open
The development of MASH in mice—does housing temperature make a real difference?
View article: Intestinal FGF15 regulates bile acid and cholesterol metabolism but not glucose and energy balance
Intestinal FGF15 regulates bile acid and cholesterol metabolism but not glucose and energy balance Open
Fibroblast growth factor 15/19 (FGF15/19, mouse/human ortholog) is expressed in the ileal enterocytes of the small intestine and released postprandially in response to bile acid absorption. Previous reports of FGF15-/- mice have limited ou…
View article: A Diet High in Fat and Fructose Induces Early Hepatic Mitochondrial Aging
A Diet High in Fat and Fructose Induces Early Hepatic Mitochondrial Aging Open
To investigate the effect of high fructose diet on ultrastructure and content of hepatic mitochondria, we randomized 6–8 weeks old male C57Bl6/J mice to ad lib chow or high‐fat‐high‐fructose (HF2) diet for 32 weeks. HF2‐fed mice gained mor…
View article: Intestinal extracellular vesicles are altered by vertical sleeve gastrectomy
Intestinal extracellular vesicles are altered by vertical sleeve gastrectomy Open
This is the first study that investigates the impact of bariatric surgery on protein composition of intestinal extracellular vesicles. Extracellular vesicle composition is greatly altered after vertical sleeve gastrectomy and may potential…
View article: Assessment of the role of FGF15 in mediating the metabolic outcomes of murine vertical sleeve gastrectomy
Assessment of the role of FGF15 in mediating the metabolic outcomes of murine vertical sleeve gastrectomy Open
In the absence of an intact fibroblast growth factor 15 (FGF15) signaling pathway, murine vertical sleeve gastrectomy results in weight loss without all its anticipated metabolic benefits. In the absence of an intact FGF15 signaling pathwa…
View article: Supplementary Tables.
Supplementary Tables. Open
1. VSG and Sham pair-fed EVs protein enrichment analysis. Pathways and their representative genes in each respective group.2. Ingenuity pathway analysis of the proteins that were obtained from the intestinal extracellular viscles of Sham p…
View article: Proteomic Database.xlsx
Proteomic Database.xlsx Open
List of all proteins that were identified in the intestinal extracellular vesicles of Sham pair-fed and Vertical Sleeve Gastrectomy mice.
View article: Metabolic comparison of one-anastomosis gastric bypass, single-anastomosis duodenal-switch, Roux-en-Y gastric bypass, and vertical sleeve gastrectomy in rat
Metabolic comparison of one-anastomosis gastric bypass, single-anastomosis duodenal-switch, Roux-en-Y gastric bypass, and vertical sleeve gastrectomy in rat Open
These data support the use of the rat for modeling bariatric surgical procedures and highlight the ability of the OAGB to meet or exceed the metabolic improvements of RYGB. These data point to the likelihood that each surgery accomplishes …
View article: Refinement of Perioperative Feeding in a Mouse Model of Vertical Sleeve Gastrectomy
Refinement of Perioperative Feeding in a Mouse Model of Vertical Sleeve Gastrectomy Open
Provision of liquid enteral nutrition (LEN) during the perioperative period is standard practice for rodents undergoing bariatric surgery, yet these diets are associated with several challenges, including coagulation of the liquid diet wit…