Explanipedia

Efficacy of Locally Applied Flurbiprofen in Sore Throat Treatment: A Scoping Review Open

Emili Dragaš, Dejan Tomljenović, Ivan Rašić, Ivana Jurčić Čulina, Lucija Svetina , et al. · 2025

Background and Objectives: Sore throat is a common symptom that, due to its heterogeneous etiology and diverse clinical presentation, poses challenges for both accurate diagnosis and etiological treatment, making symptomatic therapy essent…

Comparing Nasal Patency Outcomes in Patients Undergoing Septoplasty with Radiofrequency Turbinate Reduction, Turbinectomy, or Valvuloplasty: A Prospective Cohort Study Open

Dejan Tomljenović, Lovro Grgurić, Mislav Knežević, Lucija Svetina, Goran Geber , et al. · 2025

Introduction: The aim of this study was to compare long-term postoperative nasal airflow and symptom improvement using both subjective and objective nasal patency outcomes after three common different types of surgical interventions in pat…

Self-Assessed Quality of Life Is Differently Impacted Depending on Diagnostic Grouping in Otorhinolaryngology: An Observational Study Open

Dragica Severinac, Ines Begović, Emili Dragaš, Goran Geber, Davor Vagić , et al. · 2025

Background and Objectives: Quality of life is significantly impacted by patients’ diagnosis perceptions, and self-assessment of quality of life is increasingly used in medicine. With this study, we aim to provide an overview of the differe…

Combined Subacromial Bursal Stem Cell Therapy and Platelet-Rich Plasma Alongside Arthroscopic Rotator Cuff Surgery Reduces Postoperative Pain and Improves Functional Outcomes: A Retrospective Study Open

Mladen Miškulin, Josip Savić, Oliver Dulić, Emili Dragaš, Andro Košec · 2025

Background/Objectives: This study investigates the benefits of incorporating stem cell therapy into arthroscopic rotator cuff repair by evaluating its impact on postoperative pain and functional recovery. Methods: A retrospective, comparat…

Correlation of Clinical Characteristics of Meniere’s Disease and Its Patient-Oriented Severity Index (MD POSI) Open

Josip Novaković, Ana Barišić, Erik Šuvak, Emili Dragaš, Petar Drviš , et al. · 2025

Background: Meniere’s disease is characterized by a triad of vertigo episodes, fluctuating hearing loss, and tinnitus. The disease is followed by a loss of quality of life in patients, with the severity depending on the individual and the …

Unclassified Functional Vestibular Disorders Open

Siniša Maslovara, Petar Drviš, Andro Košec, Tihana Mendeš, Lucija Dobrić , et al. · 2025

Functional vestibular disorders (FVDs) are the most common cause of chronic dizziness and among the most prevalent vestibular conditions in adults, representing a significant public health concern. In 2017, the Behavioral Subcommittee of t…

Combined Model of Tumor–Stroma Ratio and Tumor Budding Are Not Associated with Tumor Recurrence or Metastasis in Oral Squamous Cell Carcinoma Patients Open

Drago Boščić, Emili Dragaš, Andro Košec, Goran Geber, Čedna Tomasović‐Lončarić , et al. · 2025

Histopathological grading of oral squamous cell carcinoma is currently based on differentiation of cells, while additional histological parameters, such as the tumor–stroma ratio (TSR), tumor budding (TB), or the combined TSR/tumor budding…

The Impact of Isotonic Seawater on Subjective and Objective Nose Patency in Athletes: A Randomized Controlled Trial Open

Andro Košec, Tomislav Vlahović, Branko Šilović, Mislav Rakić, Ana Starešinić , et al. · 2025

Background/Objectives: Nasal irrigation with isotonic seawater is a known and oft-used treatment for nasal obstruction in patients with acute and chronic nasal inflammatory disease undergoing therapy with intranasal corticosteroids and ant…

Chondrosarcoma of the Jugular Foramen: A Case Report Open

Josip Prnjak, Andro Košec, Alan Pegan, Tomislav Gregurić, Jakov Ajduk · 2025

The vast majority of chondrosarcomas of the skull (CS) are located at the skull base and represent locally aggressive malignant tumors that account for 0.15% of all intracranial neoplasms. Complete surgical resection with wide surgical mar…

Glucagon-Like Peptide-1 Agonist Use in Adults With Congenital Heart Disease Open

Rashmi Thapa, Kyla Lara-Breitinger, Francisco López-Jiménez, Nishat Shama, Alexander C. Egbe , et al. · 2025

Cervical sympathetic paraganglioma: A rare case managed with embolization and surgery with successful nerve recovery Open

Ivan Raguž, Andro Košec, Vladimir Kalousek, Alan Pegan · 2025

This case contributes to refining therapeutic algorithms with minimal complications.

Laryngeal Carcinoma Characteristics Associated with Positive Margins and Endoscopic Understaging Open

Nia Labaš, Andro Košec, Mirta Peček, Tomislav Gregurić, Siniša Stevanović · 2025

Background/Objectives: The study aims to analyse the factors associated with positive margins and endoscopic understaging in laryngeal carcinoma. It also aims to assess the diagnostic accuracy of Narrow Band Imaging (NBI) in comparison to …

Salivary Cortisol Concentration Is an Objective Measure of the Physiological Response to Loud Music Open

Robert Tomljenović, Andro Košec, Livije Kalogjera, Ivana Ćelap, Domagoj Marijančević , et al. · 2024

Purpose: This study examines the potential associations between salivary cortisol concentrations and subjective stress test scores in healthy individuals subjected to sound-related, psychological, and physical stressors. Methods: This stud…

Association of adenoid hypertrophy and clinical parameters with preoperative polygraphy in pediatric patients undergoing adenoidectomy Open

Alexander Lein, Hasan Altumbabić, Miralem Đešević, Wolf‐Dieter Baumgartner, Almir Salkić , et al. · 2024

Background Adenotonsillar hypertrophy is the most frequent cause for obstructive sleep apnea (OSAS) in children. In patients with small tonsils and where adenoid size cannot be assessed, the indication for adenoidectomy often relies on cli…

A <span>MAUDE</span> database analysis on the new generation of active bone conduction hearing implants Open

Alexander Lein, Wolf‐Dieter Baumgartner, Lukas D. Landegger, Dominik Riss, Thomas Thurner , et al. · 2024

Objective To analyze medical device reports (MDR) submitted to the Food and Drug Administration's (FDA) Manufacturer and User Device Facility Experience (MAUDE) database to identify adverse events (AEs) in patients implanted with novel act…

Middle Ear Neuroendocrine Tumor: Case Report of a Tympanic Adenoma Open

Ilinko Vrebac, Filip Pavlic, Andro Košec · 2024

Middle ear neuroendocrine tumors (MeNETs) are an exceptionally rare occurrence. These benign tumors stem from the tympanic mucosa and can easily be misinterpreted by the clinician and the pathologist. Clinical characteristics, otoscopic fi…

The Relationship between Tumor Budding and Tumor Deposits in Patients with Stage III Colorectal Carcinoma Open

Zdenko Bilić, Mario Zovak, Goran Glavčić, Dubravka Mužina, Amir Ibukić , et al. · 2024

Background/Objectives: Recently, some new morphological features of colorectal cancer have been discovered as important prognostic factors; in this paper, we study the relationship between tumor budding (TB) and tumor deposits (TDs). Metho…

Ethical implications of COVID-19 management—is freedom a desired aim, or a desired means to an end? Open

Andro Košec, Filip Hergešić, Boris Zdilar, Lucija Svetina, Marko Ćurković · 2024

Most developed societies managed, due to their prosperity and resource abundance, to structure relationships among free individuals in such a way to leave them fundamentally unstructured, according to the free market principle. As the pand…

Internal jugular vein thrombosis caused by invasive pharyngeal cancer: a case report and literature review Open

Filip Tudor, Andro Košec, Alan Pegan · 2024

Hypercalcemia Associated With Severe Dysphagia in a Patient With Parathyroid Adenoma and Significant Cervical Spondylophytes Open

Duje Čulina, Mirta Peček, Tomislav Gregurić, Ivana Aras, Andro Košec , et al. · 2024

Although aphagia is not a typical presenting symptom of parathyroid adenoma, it should be noted in the differential diagnosis.

Utjecaj bolesti uzrokovane koronavirusom na primarnu i tercijarnu razinu zdravstvene zaštite iz perspektive otorinolaringologa Open

Mirta Peček, Siniša Stevanović, Marijana Peček Vidaković, Andro Košec · 2024

Cilj istraživanja: Pandemija koronavirusa ima značajan utjecaj na društvo i zdravstveni sustav. Cilj ovoga rada je usporediti podatke o broju i strukturi dijagnoza i obavljenih pregleda iz područja otorinolaringologije i kirurgije glave i …

Multifocal metachronous occurence of different hystologic sinonasal-type papilloma Open

Jakov Ajduk, Mirta Peček, Marija Pierobon, Iva Mažić, Tomislav Gregurić , et al. · 2024

Introduction: Sinonasal-type papilloma is a very rare tumor, most commonly connected with the sinonasal space, and very rarely with the middle ear. Primary tumors of the temporal bone are extremely rare and only 28 cases have been describe…

Systematic Review of Current Audiological Treatment Options for Patients with Treacher Collins Syndrome (TCS) and Surgical and Audiological Experiences of an Otorhinolaryngologist with TCS Open

Ivana Marinac, Robert Trotić, Andro Košec · 2024

Treacher Collins syndrome (TCS) is a rare congenital craniofacial condition that affects approximately one out of fifty thousand births. Different ratios of TCS patients have conductive hearing loss: 88%1 vs. 91.4–100.00%2. For this reason…

Assessing Symptomatic Hypocalcemia Risk After Total Thyroidectomy: A Prospective Study Open

Andro Košec, Ana Gašić, Filip Hergešić, Ivan Rašić, Vesna Košec , et al. · 2024

Introduction The most common postoperative complication of total thyroidectomy is hypocalcemia, usually monitored using serum parathyroid hormone and calcium values. Objective To identify the most accurate predictors of hypocalcemia, const…

Long lasting atrophic glossitis due to autoimmune atrophic gastritis Open

Filip Miletić, Vladimir Bauer, Andro Košec, Sonja Radić · 2024

Autoimmune gastritis is a primary chronic inflammatory disease of the stomach mucosa caused by a pathologic autoimmune response directed against H/K -ATPase. Gastric lesions lead to sideropenic anemia due to iron malabsorption, megaloblast…

Salivary cortisone as potential predictor of occupational exposure to noise and related stress Open

Roko Žaja, Sanja Stipičević, Milan Milošević, Andro Košec, Jakov Ajduk , et al. · 2023

Salivary cortisone strongly correlates with serum cortisol, and since it is less invasive to measure salivary cortisone than serum cortisol and easier than to measure cortisol in saliva, as its concentrations are much lower, we wanted to c…

In search of new stratification strategies: tissue proteomic profiling of papillary thyroid microcarcinoma in patients with localized disease and lateral neck metastases Open

Filip Matovinović, Rudjer Novak, Stela Hrkač, Grgur Salai, Marko Močibob , et al. · 2023

Dedifferentiated Primary Parosteal Osteosarcoma of the Temporal Bone in a 19-Year-Old Patient: A Case Report Open

Andro Košec, Domagoj Šarić, Hrvoje Čupić, Jakov Ajduk · 2023

Osteosarcoma is the most common primary malignant tumor affecting the bone but is a rare occurrence in the head and neck region. Complete surgical resection with wide surgical margins is currently the main treatment strategy for osteosarco…

Wearing masks to prevent one epidemic may mask another Open

Lucija Svetina, Andro Košec · 2023

Background With attempts at lifting most COVID-19 pandemic-related restrictions, other common respiratory viruses have caused more health concern than in earlier seasons in pediatric populations. Objective To explore the role of non-pharma…

In search of new stratification strategies: Tissue proteomic profiling of papillary thyroid microcarcinoma in patients with localized disease and lateral neck metastases Open

Filip Matovinović, Rudjer Novak, Stela Hrkač, Grgur Salai, Marko Močibob , et al. · 2023

Introduction: Papillary thyroid carcinomas (PTC) are the most common thyroid malignancies that are often diagnosed as microcarcinomas when the tumour is less than one centimetre in diameter. Currently, there are no valid stratification str…

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