Jan Mieszkowski
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View article: Single high-dose vitamin D supplementation impacts ultramarathon-induced changes in serum levels of bone turnover markers: a double-blind randomized controlled trial
Single high-dose vitamin D supplementation impacts ultramarathon-induced changes in serum levels of bone turnover markers: a double-blind randomized controlled trial Open
The observed attenuation of post-exercise bone resorption and enhancement of bone formation suggest that vitamin D supplementation may modulate bone metabolism in response to extreme physical exertion, potentially through effects on calciu…
View article: Changes in insulin, leptin, resistin and irisin levels and their associations with blood pressure after an 8-week supervised, online “HIIT Mama” program vs. self-performed moderate-to-vigorous physical activity during pregnancy – A randomized controlled trial
Changes in insulin, leptin, resistin and irisin levels and their associations with blood pressure after an 8-week supervised, online “HIIT Mama” program vs. self-performed moderate-to-vigorous physical activity during pregnancy – A randomized controlled trial Open
We aimed to determine changes in insulin, leptin, resistin, and irisin levels and their associations with blood pressure (BP) during pregnancy, following an 8-week high-intensity interval training (HIIT) or a self-performed moderate-to-vig…
View article: Direct effects of remote ischemic preconditioning on post-exercise-induced changes in kynurenine metabolism
Direct effects of remote ischemic preconditioning on post-exercise-induced changes in kynurenine metabolism Open
Purpose Tryptophan (TRP) degradation through the kynurenine pathway is responsible for converting 95% of free TRP into kynurenines, which modulate skeletal muscle bioenergetics, immune and central nervous system activity. Therefore, change…
View article: Integrative Metagenomic and Blood Biomarker Analysis Reveals Distinct Metabolic Responses to Aerobic and Anaerobic Interventions in Athletic and Non-Athletic Individuals
Integrative Metagenomic and Blood Biomarker Analysis Reveals Distinct Metabolic Responses to Aerobic and Anaerobic Interventions in Athletic and Non-Athletic Individuals Open
Background The gut microbiome influences physiological responses to exercise through interactions with inflammatory markers and metabolite production. Athletes often exhibit a more diverse gut microbiome that is associated with improved pe…
View article: Single and consecutive 10-day remote ischemic preconditioning modify physical performance, post-exercise exerkine levels, and inflammation
Single and consecutive 10-day remote ischemic preconditioning modify physical performance, post-exercise exerkine levels, and inflammation Open
Purpose Remote ischemic preconditioning (RIPC) is a method of protection against induced ischemia reperfusion injury, and an increasing number of studies showed some of its inconclusive ergogenic effects in sports. RIPC involves short cycl…
View article: Joint position and force senses in young female tennis players and untrained adolescents
Joint position and force senses in young female tennis players and untrained adolescents Open
The aim of the study was to determine the differences between tennis players and untrained peers in the development of upper limb proprioception in 10–15-year-olds. A group of 67 girls (12.75 ± 1.46 years old), including 33 tennis players …
View article: One-year developmental changes in motor coordination and tennis skills in 10–12-year-old male and female tennis players
One-year developmental changes in motor coordination and tennis skills in 10–12-year-old male and female tennis players Open
We conclude that motor coordination and tennis skills development over 1 year is age-, sex-, and task-dependent, with the 10-12-year-old male tennis players performing better in tennis skills and overall motor coordination than females.
View article: Supplementation with n-3 polyunsaturated fatty acids does not impact physical performance but affects n-6 polyunsaturated fatty acid levels
Supplementation with n-3 polyunsaturated fatty acids does not impact physical performance but affects n-6 polyunsaturated fatty acid levels Open
Although the usual focus is on how n-3 PUFA supplementation affects athletes’ health, questions remain as to whether short-term supplementation affects anaerobic performance and how this type of supplementation is associated with exercise-…
View article: Effect of Single High-Dose Vitamin D3 Supplementation on Post-Ultra Mountain Running Heart Damage and Iron Metabolism Changes: A Double-Blind Randomized Controlled Trial
Effect of Single High-Dose Vitamin D3 Supplementation on Post-Ultra Mountain Running Heart Damage and Iron Metabolism Changes: A Double-Blind Randomized Controlled Trial Open
Exercise-induced inflammation can influence iron metabolism. Conversely, the effects of vitamin D3, which possesses anti-inflammatory properties, on ultramarathon-induced heart damage and changes in iron metabolism have not been investigat…
View article: Acute inflammatory response following lower-and upper-body Wingate anaerobic test in elite gymnasts in relation to iron status
Acute inflammatory response following lower-and upper-body Wingate anaerobic test in elite gymnasts in relation to iron status Open
Introduction: Artistic gymnastics is one of the most demanding sports disciplines, with the athletes demonstrating extremely high levels of explosive power and strength. Currently, knowledge of the effect of gymnastic training adaptation o…
View article: Ubiquinone (Coenzyme Q-10) Supplementation Influences Exercise-Induced Changes in Serum 25(OH)D3 and the Methyl-Arginine Metabolites: A Double-Blind Randomized Controlled Trial
Ubiquinone (Coenzyme Q-10) Supplementation Influences Exercise-Induced Changes in Serum 25(OH)D3 and the Methyl-Arginine Metabolites: A Double-Blind Randomized Controlled Trial Open
Researchers have studied the effects of exercise on serum methyl-arginine and vitamin D metabolites; however, the effects of exercise combined with antioxidants are not well documented. Since oxidative stress affects the metabolism of vita…
View article: One-year Developmental Changes in Motor Coordination and Technical Preparation in 10–12-year-old Male and Female Tennis Players
One-year Developmental Changes in Motor Coordination and Technical Preparation in 10–12-year-old Male and Female Tennis Players Open
Background: To date, no longitudinal studies have been conducted on the differences in the development of motor coordination between boys and girls in relation to changes in their technical preparation level in tennis. Therefore, the aim o…
View article: Microbiome features associated with performance measures in athletic and non-athletic individuals: A case-control study
Microbiome features associated with performance measures in athletic and non-athletic individuals: A case-control study Open
The influence of human gut microbiota on health and disease is now commonly appreciated. Therefore, it is not surprising that microbiome research has found interest in the sports community, hoping to improve health and optimize performance…
View article: The acute effect of maximal exercise test and chronic impact of an 8-week HIIT program on albuminuria and kidney function in the 2nd and 3rd trimester of physiological pregnancy.
The acute effect of maximal exercise test and chronic impact of an 8-week HIIT program on albuminuria and kidney function in the 2nd and 3rd trimester of physiological pregnancy. Open
Objectives. Physical activity is an important part of healthy lifestyle and should be continued during uncomplicated pregnancy. Several studies have suggested that most of the pregnant women had no contraindications to perform exercises. T…
View article: Vitamin D Supplementation Influences Ultramarathon-Induced Changes in Serum Amino Acid Levels, Tryptophan/Branched-Chain Amino Acid Ratio, and Arginine/Asymmetric Dimethylarginine Ratio
Vitamin D Supplementation Influences Ultramarathon-Induced Changes in Serum Amino Acid Levels, Tryptophan/Branched-Chain Amino Acid Ratio, and Arginine/Asymmetric Dimethylarginine Ratio Open
Exercise affects serum levels of amino acids and their metabolites, with important metabolic consequences. Since vitamin D impacts skeletal muscle protein degradation, we hypothesised that it would also impact exercise-induced changes in s…
View article: Microbiome Features Associated with Performance Measures in Non-Athletic and Athletic Individuals
Microbiome Features Associated with Performance Measures in Non-Athletic and Athletic Individuals Open
The influence of human gut microbiota on health and disease is now well established. Therefore, it is not surprising that microbiome research has found applications within the sports community, hoping to improve health and optimize perform…
View article: #3594 CHANGES IN ALBUMINURIA AND KIDNEY FUNCTION AFTER 8 WEEK HIGH-INTENSITY INTERVAL TRAINING PROGRAM IN 2ND AND 3RD TRIMESTER OF PHYSIOLOGICAL PREGNANCY
#3594 CHANGES IN ALBUMINURIA AND KIDNEY FUNCTION AFTER 8 WEEK HIGH-INTENSITY INTERVAL TRAINING PROGRAM IN 2ND AND 3RD TRIMESTER OF PHYSIOLOGICAL PREGNANCY Open
Background and Aims Physical exercise is the best prophylaxis of many disorders and should be continued during uncomplicated pregnancy. Several studies suggested that most pregnant women had no contraindications to perform intensive exerci…
View article: Effect of Supplementation with Black Chokeberry (Aronia melanocarpa) Extract on Inflammatory Status and Selected Markers of Iron Metabolism in Young Football Players: A Randomized Double-Blind Trial
Effect of Supplementation with Black Chokeberry (Aronia melanocarpa) Extract on Inflammatory Status and Selected Markers of Iron Metabolism in Young Football Players: A Randomized Double-Blind Trial Open
The use of herbal medicinal products and supplements in amateur and professional sports has increased in the last decades. This is because most of these products and supplements contain bioactive compounds with a variety of biological prop…
View article: Direct Effects of Vitamin D Supplementation on Ultramarathon-Induced Changes in Kynurenine Metabolism
Direct Effects of Vitamin D Supplementation on Ultramarathon-Induced Changes in Kynurenine Metabolism Open
In humans, most free tryptophan is degraded via kynurenine pathways into kynurenines. Kynurenines modulate the immune system, central nervous system, and skeletal muscle bioenergetics. Consequently, kynurenine pathway metabolites (KPMs) ha…
View article: CCL2 Gene Expression and Protein Level Changes Observed in Response to Wingate Anaerobic Test in High-Trained Athletes and Non-Trained Controls
CCL2 Gene Expression and Protein Level Changes Observed in Response to Wingate Anaerobic Test in High-Trained Athletes and Non-Trained Controls Open
Intensive, acute exercise may bring a large systemic inflammatory response marked by substantial increases in inflammatory cytokines and chemokines. One such chemokines–CCL2–is a key factor involved in inflammatory reaction to exercise. Th…
View article: Implications of Adipose Tissue Content for Changes in Serum Levels of Exercise-Induced Adipokines: A Quasi-Experimental Study
Implications of Adipose Tissue Content for Changes in Serum Levels of Exercise-Induced Adipokines: A Quasi-Experimental Study Open
Human adipocytes release multiple adipokines into the bloodstream during physical activity. This affects many organs and might contribute to the induction of inflammation. In this study, we aimed to assess changes in circulating adipokine …
View article: Elbow Joint Position and Force Senses in Young and Adult Untrained People and Gymnasts
Elbow Joint Position and Force Senses in Young and Adult Untrained People and Gymnasts Open
Joint position (JPS) and force senses (FS) are the proprioception modalities. While the development of JPS was investigated both in children/adult and athlete/untrained conditions, there is a lack of insight into the development of FS. Ove…
View article: Gross motor coordination and their relationship with body mass and physical activity level during growth in Children aged 8–11 years old: a longitudinal and allometric approach
Gross motor coordination and their relationship with body mass and physical activity level during growth in Children aged 8–11 years old: a longitudinal and allometric approach Open
Background Gross motor coordination (GMC) is fundamental to the harmonious development of physical skills during the growth of children. This research aimed to explore the developmental changes in GMC during childhood, having controlled fo…
View article: Remote Ischemic Preconditioning Reduces Marathon-Induced Oxidative Stress and Decreases Liver and Heart Injury Markers in the Serum
Remote Ischemic Preconditioning Reduces Marathon-Induced Oxidative Stress and Decreases Liver and Heart Injury Markers in the Serum Open
Clinical studies continue to provide evidence of organ protection by remote ischemic preconditioning (RIPC). However, there is lack of insight into impact of RIPC on exercise-induce changes in human organs’ function. We here aimed to eluci…
View article: cfDNA Changes in Maximal Exercises as a Sport Adaptation Predictor
cfDNA Changes in Maximal Exercises as a Sport Adaptation Predictor Open
Changes of circulating free plasma DNA (cfDNA) are associated with different types of tissue injury, including those induced by intensive aerobic and anaerobic exercises. Observed changes are dependent from induced inflammation, and thus i…
View article: Effect of 10 consecutive days of remote ischemic preconditioning on local neuromuscular performance
Effect of 10 consecutive days of remote ischemic preconditioning on local neuromuscular performance Open
10 days of RIPC induced neuromuscular performance changes in the quadriceps muscle. Even though there were no changes in task to failure performance, RIPC showed EMG changes limited to rectus femoris and increased late RTD in MVC task.
View article: Does the PPARA Intron 7 Gene Variant (rs4253778) Influence Performance in Power/Strength‐Oriented Athletes? A Case‐Control Replication Study in three Cohorts of European Gymnasts
Does the PPARA Intron 7 Gene Variant (rs4253778) Influence Performance in Power/Strength‐Oriented Athletes? A Case‐Control Replication Study in three Cohorts of European Gymnasts Open
Athletic ability is influenced by several exogenous and endogenous factors including genetic component. Hundreds of gene variants have been proposed as potential genetic markers associated with fitness-related phenotypes as well as elite-l…
View article: Single High-Dose Vitamin D Supplementation as an Approach for Reducing Ultramarathon-Induced Inflammation: A Double-Blind Randomized Controlled Trial
Single High-Dose Vitamin D Supplementation as an Approach for Reducing Ultramarathon-Induced Inflammation: A Double-Blind Randomized Controlled Trial Open
Purpose: A growing number of studies indicate the importance of vitamin D supplementation for sports performance. However, the effects of a single high-dose vitamin D supplementation on ultramarathon-induced inflammation have not been inve…