Andy Ambrus
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View article: The Immune Landscape of Canine Soft Tissue Sarcomas as a Model for Human Soft Tissue Sarcomas
The Immune Landscape of Canine Soft Tissue Sarcomas as a Model for Human Soft Tissue Sarcomas Open
Background/Objectives: Soft tissue sarcomas (STS) remain a therapeutic challenge due to their limited response to radiation and conventional chemotherapies. While recent advances in immunotherapy have improved outcomes in several cancers, …
View article: Characterization of a Broadly Reactive Anti-CD40 Agonistic Monoclonal Antibody for Potential Use as an Adjuvant
Characterization of a Broadly Reactive Anti-CD40 Agonistic Monoclonal Antibody for Potential Use as an Adjuvant Open
Lack of safe and effective adjuvants is a major hindrance to the development of efficacious vaccines. Signaling via CD40 pathway leads to enhanced antigen processing and presentation, nitric oxide expression, pro-inflammatory cytokine expr…
View article: Pancreatic neuroendocrine tumors in twelve baboons (<i>Papio</i> spp.)
Pancreatic neuroendocrine tumors in twelve baboons (<i>Papio</i> spp.) Open
Background Pancreatic neuroendocrine tumors ( PNET s) are rare in nonhuman primates and in humans. Methods Twenty‐one PNET s from twelve female baboons ( Papio spp.) from the Southwest National Primate Research Center were evaluated using …