Explanipedia

Clinically Interpretable Survival Risk Stratification in Head and Neck Cancer Using Bayesian Networks and Markov Blankets Open

Keyur D Shah, Ibrahim Chamseddine, Xiaohan Yuan, Sibo Tian, Richard L. J. Qiu , et al. · 2025

The effect of interfractional variation on delivered dose with ultrahypofractionated pencil beam scanning proton therapy for localized prostate cancer Open

Keyur D Shah, Duncan Bohannon, Sagar A. Patel, Chih‐Wei Chang, Vishal R. Dhere , et al. · 2025

Purpose/objectives Proton stereotactic body radiotherapy (SBRT) using the pencil beam scanning (PBS) technique is increasingly used for localized prostate cancer (PCa) due to its potential for superior normal tissue sparing. However, inter…

Photon-counting CT in cancer radiotherapy: technological advances and clinical benefits Open

K. Shah, Jun Zhou, Justin Roper, Anees Dhabaan, Hania Al‐Hallaq , et al. · 2025

Photon-counting computed tomography (PCCT) marks a significant advancement over conventional Energy-integrating detector CT systems. This review highlights PCCT’s superior spatial and contrast resolution, reduced radiation dose, and multi-…

DOSE ESCALATION TRIAL OF PROTON FLASH-RT TO SPINAL CORD IN A LARGE ANIMAL MODEL: QUANTIFICATION OF THE FLASH EFFECT Open

Sibo Tian, Mingyao Zhu, Soumon Rudra, Anees Dhabaan, Benjamin W. Fischer‐Valuck , et al. · 2024

Multi‐institutional consensus on machine QA for isochronous cyclotron‐based systems delivering ultra‐high dose rate (FLASH) pencil beam scanning proton therapy in transmission mode Open

Kees Spruijt, Sina Mossahebi, Haibo Lin, Eunsin Lee, J. K. Kraus , et al. · 2023

Background The first clinical trials to assess the feasibility of FLASH radiotherapy in humans have started (FAST‐01, FAST‐02) and more trials are foreseen. To increase comparability between trials it is important to assure treatment quali…

Measurement of the time structure of FLASH beams using prompt gamma rays and secondary neutrons as surrogates Open

Serdar Charyyev, Ruirui Liu, Xiaofeng Yang, Jun Zhou, Anees Dhabaan , et al. · 2023

Objective . The aim of this study was to investigate the feasibility of online monitoring of irradiation time (IRT) and scan time for FLASH proton radiotherapy using a pixelated semiconductor detector. Approach . Measurements of the time s…

Characterization of 250 MeV Protons from the Varian ProBeam PBS System for FLASH Radiation Therapy Open

Serdar Charyyev, Chih‐Wei Chang, Mingyao Zhu, Liyong Lin, K Langen , et al. · 2023

Measurement of the time structure of FLASH beams using prompt gamma rays and secondary neutrons as surrogates Open

Serdar Charyyev, Ruirui Liu, Xiaofeng Yang, Jun Zhou, Anees Dhabaan , et al. · 2022

We aim to investigate the feasibility of online monitoring of irradiation time (IRT) and scan time for FLASH radiotherapy using a pixelated semiconductor detector. Measurements of the time structure of FLASH irradiations were performed usi…

Characterization of 250 MeV protons from Varian ProBeam pencil beam scanning system for FLASH radiation therapy Open

Serdar Charyyev, Chih‐Wei Chang, Mingyao Zhu, Liyong Lin, K Langen , et al. · 2022

Recently, shoot-through proton FLASH has been proposed where the highest energy is extracted from the cyclotron to maximize the dose rate (DR). Even though our proton pencil beam scanning system can deliver 250 MeV (the highest energy), it…

Synthesizing high‐resolution magnetic resonance imaging using parallel cycle‐consistent generative adversarial networks for fast magnetic resonance imaging Open

Huiqiao Xie, Yang Lei, Tonghe Wang, Justin Roper, Anees Dhabaan , et al. · 2021

Purpose The common practice in acquiring the magnetic resonance (MR) images is to obtain two‐dimensional (2D) slices at coarse locations while keeping the high in‐plane resolution in order to ensure enough body coverage while shortening th…

Unsupervised Learning-Based CBCT-CT Deformable Image Registration for CBCT-Guided Abdominal Radiotherapy Open

Xiaofeng Yang, Yuanxi Fu, Yang Lei, Tao Wang, Jacob Wynne , et al. · 2021

Head-and-neck organs-at-risk auto-delineation using dual pyramid networks for CBCT-guided adaptive radiotherapy Open

Xianjin Dai, Yang Lei, Tonghe Wang, Anees Dhabaan, Mark W. McDonald , et al. · 2021

Organ-at-risk (OAR) delineation is a key step for cone-beam CT (CBCT) based adaptive radiotherapy planning that can be a time-consuming, labor-intensive, and subject-to-variability process. We aim to develop a fully automated approach aide…

Synthetic MRI-aided Head-and-Neck Organs-at-Risk Auto-Delineation for CBCT-guided Adaptive Radiotherapy Open

Xianjin Dai, Yang Lei, Tonghe Wang, Anees Dhabaan, Mark W. McDonald , et al. · 2020

Purpose: Organ-at-risk (OAR) delineation is a key step for cone-beam CT (CBCT) based adaptive radiotherapy planning that can be a time-consuming, labor-intensive, and subject-to-variability process. We aim to develop a fully automated appr…

Prospective International Pilot Study Evaluating the Efficacy of a Self-Guided Contouring Teaching Module With Integrated Feedback for Transitioning From 2D to 3D Treatment Planning Open

Mustafa Abugideiri, Eduard Schreibmann, Jeffrey M. Switchenko, Mark W. McDonald, Jonathan J. Beitler , et al. · 2019

PURPOSE Transitioning from two-dimensional to three-dimensional treatment planning requires developing contouring skills. Contouring atlases are excellent resources, but they do not provide users active feedback. Developing countries may n…

A Prospective International Pilot Study Evaluating the Efficacy of a Self-Guided Contouring Teaching Module with Integrated Feedback for Transitioning from 2D to 3D Treatment Planning Open

Mustafa Abugideiri, Eduard Schreibmann, Jeffrey M. Switchenko, Mark W. McDonald, Jonathan J. Beitler , et al. · 2019

Learning‐based <span>CBCT</span> correction using alternating random forest based on auto‐context model Open

Yang Lei, Xiangyang Tang, Kristin Higgins, Jolinta Lin, Jiwoong Jeong , et al. · 2018

Purpose Quantitative Cone Beam CT ( CBCT ) imaging is increasing in demand for precise image‐guided radiotherapy because it provides a foundation for advanced image‐guided techniques, including accurate treatment setup, online tumor deline…

MRI-based treatment planning for brain stereotactic radiosurgery: Dosimetric validation of a learning-based pseudo-CT generation method Open

Tonghe Wang, Nivedh Manohar, Yang Lei, Anees Dhabaan, Hui‐Kuo G. Shu , et al. · 2018

Does size matter? Investigating the optimal planning target volume margin for postoperative stereotactic radiosurgery to resected brain metastases Open

Jaymin Jhaveri, Mudit Chowdhary, Xinyan Zhang, Robert H. Press, Jeffrey M. Switchenko , et al. · 2018

OBJECTIVE The optimal margin size in postoperative stereotactic radiosurgery (SRS) for brain metastases is unknown. Herein, the authors investigated the effect of SRS planning target volume (PTV) margin on local recurrence and symptomatic …

Improving image quality of cone-beam CT using alternating regression forest Open

Xiangyang Tang, Kristin Higgins, Anees Dhabaan, Hyunsuk Shim, Walter J. Curran , et al. · 2018

We propose a CBCT image quality improvement method based on anatomic signature and auto-context alternating regression forest. Patient-specific anatomical features are extracted from the aligned training images and served as signatures for…

A denoising algorithm for CT image using low-rank sparse coding Open

Dong Xu, Tian Liu, Zhengyang Zhou, Xue Dong, Anees Dhabaan , et al. · 2018

We propose a denoising method of CT image based on low-rank sparse coding. The proposed method constructs an adaptive dictionary of image patches and estimates the sparse coding regularization parameters using the Bayesian interpretation. …

A Leaning-Based Method to Improve Cone Beam CT Image Quality for Adaptive Radiation Therapy Open

Xiaofeng Yang, Yang Lei, Kristin Higgins, Xue Dong, T. Liu , et al. · 2017

Image-based metal artifact reduction in x-ray computed tomography utilizing local anatomical similarity Open

Xue Dong, Xiaofeng Yang, J Rosenfield, Eric Elder, Anees Dhabaan · 2017

X-ray computed tomography (CT) is widely used in radiation therapy treatment planning in recent years. However, metal implants such as dental fillings and hip prostheses can cause severe bright and dark streaking artifacts in reconstructed…

Quality Improvement Steps From Implementation of Radiation Oncology Incident Learning System (RO-ILS) Open

O.C. Gartin, Kristen Burnham, Anees Dhabaan, A.L. Breakstone, Kyle Gress , et al. · 2016

Pretreatment Quality Assurance for Stereotactic Body Radiation Therapy (SBRT): Feasibility of Weekly “SBRT Rounds” in a High-Volume, Multicenter Academic Practice Open

James Parks, Natia Esiashvili, Pretesh Patel, Joseph W. Shelton, Anees Dhabaan , et al. · 2016

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