Asif Khalid
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View article: PancreaSeq Genomic Classifier (PancreaSeq GC) Improves Pancreatic Cyst Classification and Detection of Advanced Neoplasia: A Multi-institutional Validation Study
PancreaSeq Genomic Classifier (PancreaSeq GC) Improves Pancreatic Cyst Classification and Detection of Advanced Neoplasia: A Multi-institutional Validation Study Open
Background The preoperative classification of pancreatic cysts and detection of advanced neoplasia (high-grade dysplasia/pancreatic ductal adenocarcinoma [PDAC]) represents a significant diagnostic challenge. A prospective, multi-instituti…
View article: Artificial intelligence in healthcare: applications, challenges, and future directions. A narrative review informed by international, multidisciplinary expertise
Artificial intelligence in healthcare: applications, challenges, and future directions. A narrative review informed by international, multidisciplinary expertise Open
Objectives This narrative review evaluates the role of artificial intelligence (AI) in healthcare, summarizing its historical evolution, current applications across medical and surgical specialties, and implications for allied health profe…
View article: From obstruction to ischaemia: a systematic review and meta-analysis on the diagnostic accuracy of CT scans in identifying small and large bowel obstruction, underlying causes and predicting critical complications in adults
From obstruction to ischaemia: a systematic review and meta-analysis on the diagnostic accuracy of CT scans in identifying small and large bowel obstruction, underlying causes and predicting critical complications in adults Open
Objectives To evaluate the diagnostic accuracy of CT in identifying small and large bowel obstruction and associated complications, including ischaemia and perforation, in adult patients. Design Systematic review and meta-analysis reported…
View article: From obstruction to ischemia: A systematic review and meta-analysis on the diagnostic accuracy of CT scans in identifying small and large bowel obstruction, underlying causes, and predicting critical complications in adults v1
From obstruction to ischemia: A systematic review and meta-analysis on the diagnostic accuracy of CT scans in identifying small and large bowel obstruction, underlying causes, and predicting critical complications in adults v1 Open
This protocol presents the methodological framework for conducting a systematic review and meta-analysis to evaluate the diagnostic accuracy of computed tomography (CT) in identifying small and large bowel obstruction and associated compli…
View article: Evaluation of Trauma-Induced Coagulopathy by Systematic Insights Into Pathophysiology and Advances in Emergency Resuscitation
Evaluation of Trauma-Induced Coagulopathy by Systematic Insights Into Pathophysiology and Advances in Emergency Resuscitation Open
Trauma-induced coagulopathy (TIC) exists as a fatal complication that develops from severe injuries and substantially increases patient mortality. Effective knowledge of TIC pathophysiology, together with optimized resuscitation strategies…
View article: Maternal-Fetal Endocrine Interface: A Systematic Review of the Clinicopathological Assessment of Hypothalamic-Pituitary-Adrenal Axis Dysregulation in Pregnancy Complications
Maternal-Fetal Endocrine Interface: A Systematic Review of the Clinicopathological Assessment of Hypothalamic-Pituitary-Adrenal Axis Dysregulation in Pregnancy Complications Open
Background: The hypothalamic-pituitary-adrenal (HPA) axis played a critical role in balancing maternal stress responses during pregnancy. This systematic review aimed to evaluate the dysregulation of the HPA axis and its link to pregnancy …
View article: Whispers in the air: Designing acoustic classifiers to detect fruit flies from afar
Whispers in the air: Designing acoustic classifiers to detect fruit flies from afar Open
Detecting weak wingbeats of a flying bug is a challenging problem in uncontrolled outdoor settings. In this work, we show that proper treatment of environmental noise is a key factor in robust acoustic classifier design and propose a novel…
View article: Microbial Biomarkers Helpful in Early Detection of Cancer: Prognosis and Suitable Treatment
Microbial Biomarkers Helpful in Early Detection of Cancer: Prognosis and Suitable Treatment Open
The significance of microbial biomarkers in cancer detection and prognosis garners heightened interest, with considerable implications for early diagnosis, tailored treatment, and enhanced patient outcomes. Microbial dysbiosis, especially …
View article: Beyond Tradition: A study of relationship evolution in Millennials and Gen Z
Beyond Tradition: A study of relationship evolution in Millennials and Gen Z Open
This paper examines the generational gaps that are observed in the pair bonding patterns of Gen Z and Millennials and how two of these younger generations are getting ahead of their parental generation in redefining their romantic and inti…
View article: Detection of Alternative Lengthening of Telomeres via Chromogenic In Situ Hybridization for the Prognostication of PanNETs and Other Neoplasms
Detection of Alternative Lengthening of Telomeres via Chromogenic In Situ Hybridization for the Prognostication of PanNETs and Other Neoplasms Open
Molecular studies have shown alternative lengthening to telomeres (ALT) to be an important prognostic biomarker of shorter relapse-free survival (RFS) for patients with pancreatic neuroendocrine tumors (PanNETs) and other neoplasms. Howeve…
View article: Natural history of spontaneous pancreatic portal vein fistulae: A systematic review of the literature
Natural history of spontaneous pancreatic portal vein fistulae: A systematic review of the literature Open
PPVF is a rare and potentially fatal condition, though rates of bleeding complication and death were relatively low in this population. High-quality observational studies are needed to better understand the pathophysiology and natural hist…
View article: Double Balloon Enteroscopy Guided Band Ligation and Auto-Amputation for Treatment of a Large Hemorrhagic Lymphangioma
Double Balloon Enteroscopy Guided Band Ligation and Auto-Amputation for Treatment of a Large Hemorrhagic Lymphangioma Open
A 65-year-old woman with history of Roux-en-Y gastric bypass presented with iron deficiency anemia. Initial evaluation with esophagogastroduodenoscopy and colonoscopy was unrevealing, thus video capsule endoscopy was performed. Fresh hemat…
View article: A Combined DNA/RNA-based Next-Generation Sequencing Platform to Improve the Classification of Pancreatic Cysts and Early Detection of Pancreatic Cancer Arising From Pancreatic Cysts
A Combined DNA/RNA-based Next-Generation Sequencing Platform to Improve the Classification of Pancreatic Cysts and Early Detection of Pancreatic Cancer Arising From Pancreatic Cysts Open
Objective: We report the development and validation of a combined DNA/RNA next-generation sequencing (NGS) platform to improve the evaluation of pancreatic cysts. Background and Aims: Despite a multidisciplinary approach, pancreatic cyst c…
View article: External nasal dilator decreases N95 respirator-related respiratory effort and symptoms in gastrointestinal endoscopy unit staff
External nasal dilator decreases N95 respirator-related respiratory effort and symptoms in gastrointestinal endoscopy unit staff Open
Background and study aims N95-filtering facepiece respirators (FFR) use is associated with physiological changes and symptoms due to impaired nasal airflow and increased breathing resistance. We prospectively studied the effect of using an…
View article: High Rate of Inappropriate Fecal Immunochemical Testing at a Large Veterans Affairs Health Care System
High Rate of Inappropriate Fecal Immunochemical Testing at a Large Veterans Affairs Health Care System Open
Veterans underwent inappropriate testing due to failure to undergo serial FIT after a negative result (37.6%), failure to complete colonoscopy following a positive FIT (27.5%), and undergoing inappropriate FIT following a recent colonoscop…
View article: Non-functional pancreatic neuroendocrine tumours: ATRX/DAXX and alternative lengthening of telomeres (ALT) are prognostically independent from ARX/PDX1 expression and tumour size
Non-functional pancreatic neuroendocrine tumours: ATRX/DAXX and alternative lengthening of telomeres (ALT) are prognostically independent from ARX/PDX1 expression and tumour size Open
Objective Recent studies have found aristaless-related homeobox gene (ARX)/pancreatic and duodenal homeobox 1 (PDX1), alpha-thalassemia/mental retardation X-linked (ATRX)/death domain-associated protein (DAXX) and alternative lengthening o…
View article: Safety and efficacy of band ligation and auto-amputation as adjunct to EMR of colonic large laterally spreading tumors, and polyps not amenable to routine polypectomy
Safety and efficacy of band ligation and auto-amputation as adjunct to EMR of colonic large laterally spreading tumors, and polyps not amenable to routine polypectomy Open
Introduction: The safety and efficacy of colonic band ligation and auto-amputation (1) as adjunct to endoscopic mucosal resection of large laterally spreading tumors and (2) for polyps not amenable to routine polypectomy due to polyp burde…