Aneesh Deshmukh
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View article: Dielectrophoresis Reveals Stimulus-Induced Remodeling of Insulin Granule Subpopulations
Dielectrophoresis Reveals Stimulus-Induced Remodeling of Insulin Granule Subpopulations Open
The pancreatic β-cell contains several functional subpopulations of insulin secretory granules (ISGs). These subpopulations vary in maturity, age, and secretory capacity. Differences in protein and lipid composition of ISGs are correlated …
View article: Robust Deep Learning-based 3D Segmentation and Morphological Analysis of Mitochondria using Soft X-ray Tomography
Robust Deep Learning-based 3D Segmentation and Morphological Analysis of Mitochondria using Soft X-ray Tomography Open
Mitochondrial morphology is crucial for cellular function, but large-scale analysis is limited by challenges in high-resolution imaging and segmentation. MitoXRNet, a compact 3D deep-learning model, efficiently segments mitochondria and nu…
View article: Classifying Biophysical Subpopulations of Insulin Secretory Granules using Quantitative Whole Cell Structure Analysis
Classifying Biophysical Subpopulations of Insulin Secretory Granules using Quantitative Whole Cell Structure Analysis Open
Pancreatic β-cells contain insulin secretory granules (ISGs), organelles where proinsulin is converted into insulin. As ISGs mature, they undergo extensive biophysical remodeling, producing a spectrum of subpopulations with heterogeneous m…
View article: Secretory stimuli distinctly regulate insulin secretory granule maturation through structural remodeling
Secretory stimuli distinctly regulate insulin secretory granule maturation through structural remodeling Open
View article: Secretory stimuli distinctly regulate insulin secretory granule maturation through structural remodeling
Secretory stimuli distinctly regulate insulin secretory granule maturation through structural remodeling Open
SUMMARY Insulin secretory granule (ISG) maturation is a crucial aspect of insulin secretion and glucose homeostasis. The regulation of this maturation remains poorly understood, especially how secretory stimuli affect ISG maturity and subc…
View article: Quantitative mapping and visualizing of insulin hormone maturation
Quantitative mapping and visualizing of insulin hormone maturation Open
Insulin is a peptide hormone secreted from pancreatic β cells to regulate blood glucose levels. Insulin maturation is dysregulated in diabetes and there are many open questions on how the cell regulates maturation. Maturation of insulin in…
View article: Classifying Biophysical Subpopulations of Insulin Secretory Granules using Quantitative Whole Cell Structure Analysis
Classifying Biophysical Subpopulations of Insulin Secretory Granules using Quantitative Whole Cell Structure Analysis Open
View article: Subcellular Feature-Based Classification of α and β Cells Using Soft X-ray Tomography
Subcellular Feature-Based Classification of α and β Cells Using Soft X-ray Tomography Open
The dysfunction of α and β cells in pancreatic islets can lead to diabetes. Many questions remain on the subcellular organization of islet cells during the progression of disease. Existing three-dimensional cellular mapping approaches face…
View article: Shopping Redefined: An Innovative System with Barcode Scanning and Bill Display
Shopping Redefined: An Innovative System with Barcode Scanning and Bill Display Open
This paper presents the development of automated shopping cart for supermarkets. This automated shopping cart reduces the shopping time of customer. This project works on Arduino UNO microcontroller, bar code scanner for scanning the produ…
View article: Quantitative Structural Mapping of Insulin Vesicle Maturation in Beta Cells
Quantitative Structural Mapping of Insulin Vesicle Maturation in Beta Cells Open
Characterizing relationships between cell structures and functions requires quantitative mesoscale mapping of intact cells showing subcellular rearrangements following stimulation.Thus, we investigated the application of soft X-ray tomogra…
View article: Automatic Car Number Plate Detection System Using OpenCv
Automatic Car Number Plate Detection System Using OpenCv Open
bstract: Automatic Number Plate Recognition (ANPR) is an issue that has received a lot of attention and has a lot of successful solutions. Due to the differences in number plate features around the world, these solutions are typically tail…