Angela Loo
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View article: P-2309. Assessment of Risk Factors Associated with Subtherapeutic Posaconazole Levels
P-2309. Assessment of Risk Factors Associated with Subtherapeutic Posaconazole Levels Open
Background There is significant variability in patient serum posaconazole levels, and it is unclear what characteristics increase the risk for subtherapeutic levels. Higher levels have been associated with improved outcomes. The purpose of…
View article: Initial micafungin treatment does not improve outcomes compared to fluconazole treatment in immunocompromised and critically ill patients with candidaemia
Initial micafungin treatment does not improve outcomes compared to fluconazole treatment in immunocompromised and critically ill patients with candidaemia Open
Background Candidaemia is associated with poor outcomes including high mortality rates. Controversy remains regarding whether fluconazole or an echinocandin is the optimal choice for initial candidaemia treatment, particularly among high-r…
View article: 810. Predictors of 30-Day Mortality Among Critically Ill Patients with Candidemia Identified by T2Candida Panel
810. Predictors of 30-Day Mortality Among Critically Ill Patients with Candidemia Identified by T2Candida Panel Open
Background Candidemia is associated with mortality rates exceeding 40%. However, prior studies indicate mortality may be reduced when antifungal therapy is initiated within 12 hours. The T2Candida Panel is a diagnostic assay that detects C…
View article: 680. Comparison of Extended Duration Vancomycin Regimens for <i>Clostridioides difficile</i> Infection in Patients on Prolonged Antibiotic Courses
680. Comparison of Extended Duration Vancomycin Regimens for <i>Clostridioides difficile</i> Infection in Patients on Prolonged Antibiotic Courses Open
Background Antibiotic exposure is a primary risk factor for Clostridioides difficile infection (CDI) and recurrence. We compared CDI recurrence in patients who received extended oral vancomycin (poV) after diagnosis of CDI, at a dose of q1…
View article: 958. A Required Infectious Diseases Rotation Improves Antimicrobial Stewardship Knowledge for Internal Medicine Interns
958. A Required Infectious Diseases Rotation Improves Antimicrobial Stewardship Knowledge for Internal Medicine Interns Open
Background Exposure to Infectious Diseases (ID) education is highly variable in post-graduate medical training. We report our experience with a required one-week ID consult rotation for Internal Medicine (IM) interns with a focus on antimi…
View article: Casirivimab-Imdevimab (REGN-COV2) for Mild to Moderate SARS-CoV-2 Infection in Kidney Transplant Recipients
Casirivimab-Imdevimab (REGN-COV2) for Mild to Moderate SARS-CoV-2 Infection in Kidney Transplant Recipients Open
Kidney transplant recipients are an immunocompromised population, many with comorbid diseases such as obesity, diabetes, and coronary artery disease, that may increase their risk for developing severe coronavirus disease 2019 (COVID-19).1P…
View article: Antimicrobial stewardship perspectives from a New York City hospital during the COVID-19 pandemic: Challenges and opportunities
Antimicrobial stewardship perspectives from a New York City hospital during the COVID-19 pandemic: Challenges and opportunities Open
Purpose To share challenges and opportunities for antimicrobial stewardship programs based on one center’s experience during the early weeks of the coronavirus disease 2019 (COVID-19) pandemic. Summary In the spring of 2020, New York City …
View article: Implementation of infectious diseases rapid molecular diagnostic tests and antimicrobial stewardship program involvement in acute-care hospitals
Implementation of infectious diseases rapid molecular diagnostic tests and antimicrobial stewardship program involvement in acute-care hospitals Open
A survey of acute-care hospitals found that rapid molecular diagnostic tests (RMDTs) have been widely adopted. Although many hospitals use their antimicrobial stewardship team and/or guidelines to help clinicians interpret results and opti…
View article: Implementation of Rapid Molecular Diagnostic Tests and Antimicrobial Stewardship Involvement in Acute-Care Hospitals
Implementation of Rapid Molecular Diagnostic Tests and Antimicrobial Stewardship Involvement in Acute-Care Hospitals Open
Background: In recent years, several rapid molecular diagnostic tests (RMDTs) for infectious diseases diagnostics, such as bloodstream infections (BSIs), have become available for clinical use. The extent to which RMDTs have been adopted a…
View article: ICE volume 39 issue 3 Cover and Front matter
ICE volume 39 issue 3 Cover and Front matter Open
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View article: A Hospitalist-Led Initiative to Promote Antibiotic Citizenship on Internal Medicine Teaching Services
A Hospitalist-Led Initiative to Promote Antibiotic Citizenship on Internal Medicine Teaching Services Open
BACKGROUND: Hospitalists are critical partners in antimicrobial stewardship program (ASP) efforts to improve antimicrobial use, but limited data exists on the effectiveness of ASP-hospitalist collaboration. We performed a hospitalist-led q…
View article: Outcomes Comparing Initial Short vs Long Course Echinocandin Therapy in Patients with Candidemia Caused by Fluconazole Susceptible Strains
Outcomes Comparing Initial Short vs Long Course Echinocandin Therapy in Patients with Candidemia Caused by Fluconazole Susceptible Strains Open
Background Guidelines for candidemia (CAND) treatment recommend initial echinocandin (ECHINO) therapy with transition to fluconazole (FLUC) after 5–7 days in patients with clinical stability, FLUC-susceptibility, and negative cultures; how…
View article: Combination Regimens for Treatment of Carbapenem-Resistant Klebsiella pneumoniae Bloodstream Infections
Combination Regimens for Treatment of Carbapenem-Resistant Klebsiella pneumoniae Bloodstream Infections Open
Previous studies reported decreased mortality in patients with carbapenemase-producing Klebsiella pneumoniae bloodstream infections (BSIs) treated with combination therapy but included carbapenem-susceptible and -intermediate isolates, as …
View article: Clinical Outcomes Associated with Polymyxin B Dose in Patients with Bloodstream Infections Due to Carbapenem-Resistant Gram-Negative Rods
Clinical Outcomes Associated with Polymyxin B Dose in Patients with Bloodstream Infections Due to Carbapenem-Resistant Gram-Negative Rods Open
There is significant variation in the use of polymyxin B (PMB), and optimal dosing has not been defined. The purpose of this retrospective study was to evaluate the relationship between PMB dose and clinical outcomes. We included patients …
View article: Knowledge, Attitudes, and Practices Regarding Antimicrobial Stewardship Among Antimicrobial Prescribers at Five Acute Care Hospitals
Knowledge, Attitudes, and Practices Regarding Antimicrobial Stewardship Among Antimicrobial Prescribers at Five Acute Care Hospitals Open
The survey results will be used to develop and implement clinical AS interventions at NYP. Future research efforts will focus on the identification of changes in antimicrobial prescribing practices and clinical outcomes associated with e…