Ángela María Arenas Velásquez
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View article: Guanidines Conjugated with Cell-Penetrating Peptides: A New Approach for the Development of Antileishmanial Molecules
Guanidines Conjugated with Cell-Penetrating Peptides: A New Approach for the Development of Antileishmanial Molecules Open
Leishmaniasis is a neglected tropical disease caused by a protozoan of the genus Leishmania, which has visceral and cutaneous forms. The symptoms of leishmaniasis include high fever and weakness, and the cutaneous infection also causes les…
View article: Peptide Dimerization as a Strategy for the Development of Antileishmanial Compounds
Peptide Dimerization as a Strategy for the Development of Antileishmanial Compounds Open
Leishmaniasis is recognized as a serious public health problem in Brazil and around the world. The limited availability of drugs for treatment, added to the diversity of side effects and the emergence of resistant strains, shows the import…
View article: Novel Selective and Low-Toxic Inhibitor of LmCPB2.8ΔCTE (CPB) One Important Cysteine Protease for Leishmania Virulence
Novel Selective and Low-Toxic Inhibitor of LmCPB2.8ΔCTE (CPB) One Important Cysteine Protease for Leishmania Virulence Open
Leishmaniasis is a highly prevalent, yet neglected disease caused by protozoan parasites of the genus Leishmania. In the search for newer, safer, and more effective antileishmanial compounds, we herein present a study of the mode of action…
View article: New Insights into the Mechanism of Action of the Cyclopalladated Complex (CP2) in<i>Leishmania</i>: Calcium Dysregulation, Mitochondrial Dysfunction, and Cell Death
New Insights into the Mechanism of Action of the Cyclopalladated Complex (CP2) in<i>Leishmania</i>: Calcium Dysregulation, Mitochondrial Dysfunction, and Cell Death Open
The current treatment of leishmaniasis is based on a few drugs that present several drawbacks, such as high toxicity, difficult administration route, and low efficacy. These disadvantages raise the necessity to develop novel antileishmania…
View article: Bioguided study of the Antarctic alga Himantothallus grandifolius (A. Geep & E.S.Geep) indicates 13E-Docosenamide as potential antileishmanial agent
Bioguided study of the Antarctic alga Himantothallus grandifolius (A. Geep & E.S.Geep) indicates 13E-Docosenamide as potential antileishmanial agent Open
Made available in DSpace on 2021-06-25T10:31:36Z (GMT). No. of bitstreams: 0\n Previous issue date: 2020-01-01
View article: Potential application of rLc36 protein for diagnosis of canine visceral leishmaniasis
Potential application of rLc36 protein for diagnosis of canine visceral leishmaniasis Open
Visceral leishmaniasis (VL) is fatal if left untreated. Infected dogs are important reservoirs of the disease, and thus specific identification of infected animals is very important. Several diagnostic tests have been developed for canine …
View article: Potential application of rLc36 protein for diagnosis of canine visceral leishmaniasis
Potential application of rLc36 protein for diagnosis of canine visceral leishmaniasis Open
Visceral leishmaniasis (VL) is fatal if left untreated. Infected dogs are important reservoirs of the disease, and thus specific identification of infected animals is very important. Several diagnostic tests have been developed for canine …
View article: Synthesis by combustion in solution of Zn<sub>2</sub>TiO<sub>4</sub>+Ag for photocatalytic and photodynamic applications in the visible
Synthesis by combustion in solution of Zn<sub>2</sub>TiO<sub>4</sub>+Ag for photocatalytic and photodynamic applications in the visible Open
Zn2TiO4 + Ag compounds were synthesized by the solution combustion path seeking to enhance their photocatalytic and photodynamic response in the visible. X-ray diffraction tests confirmed the formation of the phase and the presence of meta…
View article: Efficacy of a Binuclear Cyclopalladated Compound Therapy for Cutaneous Leishmaniasis in the Murine Model of Infection with Leishmania amazonensis and Its Inhibitory Effect on Topoisomerase 1B
Efficacy of a Binuclear Cyclopalladated Compound Therapy for Cutaneous Leishmaniasis in the Murine Model of Infection with Leishmania amazonensis and Its Inhibitory Effect on Topoisomerase 1B Open
Leishmaniasis is a disease found throughout the (sub)tropical parts of the world caused by protozoan parasites of the Leishmania genus. Despite the numerous problems associated with existing treatments, pharmaceutical companies continue to…
View article: Antiprotozoal Activity of the Cyclopalladated Complexes Against<i>Leishmania amazonensis</i>and<i>Trypanosoma cruzi</i>
Antiprotozoal Activity of the Cyclopalladated Complexes Against<i>Leishmania amazonensis</i>and<i>Trypanosoma cruzi</i> Open
Made available in DSpace on 2016-11-10T19:22:27Z (GMT). No. of bitstreams: 1 S0103-50532016000601032.pdf: 456253 bytes, checksum: b1c4b863c71b9368c94b45ff380db5e1 (MD5) Previous issue date: 2016