Angelo Gemignani
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View article: Pupillary Hippus as a Biomarker: Spectral Signatures and Complexity Approaches in Autonomic and Clinical Contexts
Pupillary Hippus as a Biomarker: Spectral Signatures and Complexity Approaches in Autonomic and Clinical Contexts Open
Pupillary hippus, i.e., the spontaneous bilateral oscillation of pupil diameter under constant illumination, provides a non-invasive window into autonomic and central nervous system dynamics. Despite decades of research, a unified framewor…
View article: Preliminary Findings from a Mindfulness-Based Intervention in Patients with Psychogenic Non-Epileptic Seizures
Preliminary Findings from a Mindfulness-Based Intervention in Patients with Psychogenic Non-Epileptic Seizures Open
Background/Objectives: Psychogenic non-epileptic seizures (PNES) are seizure-like episodes not caused by abnormal brain activity, often linked to emotional dysregulation, dissociation, and altered interoceptive awareness. Standardized trea…
View article: Initial Psychological Evaluation in Couples with Unexplained Infertility: Focusing on Gender Differences
Initial Psychological Evaluation in Couples with Unexplained Infertility: Focusing on Gender Differences Open
This study explored psychological distress and gender differences among couples diagnosed with unexplained infertility (UI) and undergoing evaluation for assisted reproductive treatment at the AOUP Santa Chiara Hospital in Pisa, Italy. A t…
View article: Addressing Psychological Distress in College Students Through Mindfulness Training: A Pre–Post Intervention Across Three Cohorts with Different Delivery Methods
Addressing Psychological Distress in College Students Through Mindfulness Training: A Pre–Post Intervention Across Three Cohorts with Different Delivery Methods Open
College students are particularly vulnerable to psychological distress, including anxiety, depression, and chronic stress, often triggered by academic pressure, developmental challenges, and events such as the COVID-19 pandemic. This study…
View article: Deprescription of benzodiazepines and its management according to an overlapping strategy with a low-dose multicomponent medication: a Delphi consensus
Deprescription of benzodiazepines and its management according to an overlapping strategy with a low-dose multicomponent medication: a Delphi consensus Open
Ignatia-Heel can be considered a valid opportunity for the treatment of pathological anxiety favoring the deprescription of BZDs in patients under chronic BZDs treatment and the maintenance of a good control of symptomatology, i.e., a good…
View article: The Interplay Between the Sleep Slow Oscillation and Cerebrospinal Fluid: New Vistas for Insomnia Research
The Interplay Between the Sleep Slow Oscillation and Cerebrospinal Fluid: New Vistas for Insomnia Research Open
Insomnia disorder affects about 10% of the global population, representing a major health concern. Despite the availability of evidence‐based treatments, the neurobiological mechanisms underpinning this disorder remain poorly understood. R…
View article: Sensory Substitution and Embodiment: Shaping Performance and Immersion in Teleoperated Settings
Sensory Substitution and Embodiment: Shaping Performance and Immersion in Teleoperated Settings Open
Background: Telemanipulation enables the execution of remote operations using specialized tools, often under reduced sensory input, such as lack of haptic feedback. With practice, these tools can become extensions of the user's body, a phe…
View article: FOUND Questionnaire: Mapping Stable Traits Critical for Success in Remote Operations
FOUND Questionnaire: Mapping Stable Traits Critical for Success in Remote Operations Open
This study introduces the FOUndatioNal trait-BaseD Characterization (FOUND) questionnaire, specifically developed to assess stable characteristics of perceptual, cognitive, and emotional domains critical for effective performance in mediat…
View article: Use of DORA Daridorexant for the deprescription of hypnotic medications for chronic insomnia comorbid with mood,anxiety and sedative hypnotic use disorders: a naturalistic longitudinal study
Use of DORA Daridorexant for the deprescription of hypnotic medications for chronic insomnia comorbid with mood,anxiety and sedative hypnotic use disorders: a naturalistic longitudinal study Open
Introduction Targeting insomnia may have a therapeutic value for mental disturbances. Indeed, insomnia chronic nature may necessitate switching between various insomnia approaches and medications. Daridorexant is a new pharmacological opti…
View article: Effects of DORA Daridorexant on insomnia disorder in patients with comorbid unipolar and bipolar depression: data from a naturalistic longitudinal study
Effects of DORA Daridorexant on insomnia disorder in patients with comorbid unipolar and bipolar depression: data from a naturalistic longitudinal study Open
Introduction Insomnia is the most common sleep disorder, which may favor , precipitate, and prolong mental disturbances, including mood disorders. The treatment of insomnia in the context of mood disorders may contribute to improving their…
View article: Sensory Substitution and Embodiment: Shaping Performance and Immersion in Teleoperated Settings
Sensory Substitution and Embodiment: Shaping Performance and Immersion in Teleoperated Settings Open
Background: Telemanipulation enables the execution of remote operations using specialized tools, often under reduced sensory input, such as lack of haptic feedback. With practice, these tools can become extensions of the user's body, a phe…
View article: Behavioral Avoidance Test in virtual reality (vr-BAT) and in-vivo (real-BAT) v1
Behavioral Avoidance Test in virtual reality (vr-BAT) and in-vivo (real-BAT) v1 Open
Volunteers were asked to participate in two experimental sessions separated by at least two weeks. In one session they were asked to undergo the vr-BAT, and in the other one the traditional version with a real spider (real-BAT): the order …
View article: Pupillometry reveals autonomic adjustments during diving reflex in face immersion apnea
Pupillometry reveals autonomic adjustments during diving reflex in face immersion apnea Open
The human diving reflex (DR), an innate defensive reflex triggered during periods of apnea, concurrently activates both the sympathetic and parasympathetic branches of the autonomic nervous system to regulate physiology against challenging…
View article: The Interplay of Personality Traits and Psychological Well-Being: Insights from a Study of Italian Undergraduates
The Interplay of Personality Traits and Psychological Well-Being: Insights from a Study of Italian Undergraduates Open
Objectives: The mental health and well-being of university students are crucial areas of research due to their significant impact on academic success, personal development, and overall life satisfaction. Since previous research consistentl…
View article: Beyond the hot flashes: how machine learning is uncovering the complexity of menopause-related depression
Beyond the hot flashes: how machine learning is uncovering the complexity of menopause-related depression Open
Background The transition into menopause marks a significant stage in a woman’s life, indicating the end of reproductive capability. This period, encompassing perimenopause and menopause, is characterized by declining levels of estrogen an…
View article: Psychometric Assessment of the Italian Version of the Vaccination Attitudes Examination (VAX) Scale and Exploration of Its Link With Policy Endorsement
Psychometric Assessment of the Italian Version of the Vaccination Attitudes Examination (VAX) Scale and Exploration of Its Link With Policy Endorsement Open
Two key steps in addressing the vaccination hesitancy issue are assessing the population’s attitudes toward vaccination and making measures’ availability as broad as possible (not limited to English-speaking populations). To reach the latt…
View article: Dispositional mindfulness, interoceptive awareness, and panic-agoraphobic spectrum, in a general population sample
Dispositional mindfulness, interoceptive awareness, and panic-agoraphobic spectrum, in a general population sample Open
Objective To investigate dispositional mindfulness (DM), interoceptive awareness (AI), and the occurrence of panic-agoraphobic spectrum signs and symptoms in a non-clinical population. Methods The study involved a general population sample…
View article: About Distress in Chronic Pain Conditions: A Pre–Post Study on the Effectiveness of a Mindfulness-Based Intervention for Fibromyalgia and Low Back Pain Patients
About Distress in Chronic Pain Conditions: A Pre–Post Study on the Effectiveness of a Mindfulness-Based Intervention for Fibromyalgia and Low Back Pain Patients Open
Chronic pain (CP) affects about 30% of the global population and poses significant challenges to individuals and healthcare systems worldwide. The interactions between physiological, psychological, and social factors are crucial in the ons…
View article: Loneliness and Problematic Internet Use in Adolescents: The Mediating Role of Dissociation
Loneliness and Problematic Internet Use in Adolescents: The Mediating Role of Dissociation Open
Background/Objectives. Problematic Internet uUse (PIU) is a multifaceted syndrome characterized by excessive or poorly controlled preoccupations, urges, or behaviors regarding Internet use leading to significant impairments in daily life a…
View article: How Different Treatments for Acromegaly Modulate Sleep Quality: A Psychometric Study
How Different Treatments for Acromegaly Modulate Sleep Quality: A Psychometric Study Open
Acromegaly is a rare endocrine syndrome characterized by unrestrained growth hormone (GH) secretion from a GH-secreting pituitary neuroendocrine tumor (PitNET). Data on sleep disorders are scanty and mainly linked to Obstructive Sleep Apne…
View article: Unconscious multisensory integration: behavioral and neural evidence from subliminal stimuli
Unconscious multisensory integration: behavioral and neural evidence from subliminal stimuli Open
Introduction The prevailing theories of consciousness consider the integration of different sensory stimuli as a key component for this phenomenon to rise on the brain level. Despite many theories and models have been proposed for multisen…
View article: Report from a Tibetan Monastery: EEG neural correlates of concentrative and analytical meditation
Report from a Tibetan Monastery: EEG neural correlates of concentrative and analytical meditation Open
The positive effects of meditation on human wellbeing are indisputable, ranging from emotion regulation improvement to stress reduction and present-moment awareness enhancement. Changes in brain activity regulate and support these phenomen…
View article: Obsessive-compulsive symptoms in professional tennis players
Obsessive-compulsive symptoms in professional tennis players Open
Introduction Engaging in moderate physical activity holds a vital role in our daily lives, serving as both a means of social recreation and a fundamental contributor to physical and mental wellbeing. It is also worth noting that such activ…
View article: Sense of Agency and Skills Learning in Virtual-Mediated Environment: A Systematic Review
Sense of Agency and Skills Learning in Virtual-Mediated Environment: A Systematic Review Open
Agency is central to remote actions, and it may enhance skills learning due to a partial overlap between brain structures and networks, the promotion of confidence towards a telemanipulator, and the feeling of congruence of the motor choic…
View article: Do Individual Differences in Perception Affect Awareness of Climate Change?
Do Individual Differences in Perception Affect Awareness of Climate Change? Open
One significant obstacle to gaining a widespread awareness of the ongoing climate change is the nature of its manifestations in relation to our perception: climate change effects are gradual, distributed, and sometimes seemingly contradict…
View article: Is Interoception Deficit Linking Alexithymia and Eating Spectrum Symptoms? Study on a Non-Clinical Sample of Young Adults
Is Interoception Deficit Linking Alexithymia and Eating Spectrum Symptoms? Study on a Non-Clinical Sample of Young Adults Open
We investigated if interoceptive deficits could be the link between alexithymic traits and eating spectrum manifestations in a non-clinical sample. One-hundred sixty-one young adults (mean age: 23.2 ± 2.4 years) were evaluated with the Tor…
View article: Correlated P300b and phasic pupil‐dilation responses to motivationally significant stimuli
Correlated P300b and phasic pupil‐dilation responses to motivationally significant stimuli Open
Motivationally significant events like oddball stimuli elicit both a characteristic event‐related potential (ERPs) known as P300 and a set of autonomic responses including a phasic pupil dilation. Although co‐occurring, P300 and pupil‐dila…