Angelo Orsini
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View article: Therapeutic Advances in Metastatic Prostate Cancer: A Journey from Standard of Care to New Emerging Treatment
Therapeutic Advances in Metastatic Prostate Cancer: A Journey from Standard of Care to New Emerging Treatment Open
Prostate cancer (PCa) remains one of the most prevalent malignancies among men worldwide and continues to pose significant therapeutic challenges, especially in its metastatic and castration-resistant forms. Over the past two decades, the …
View article: Histopathology and outcomes of non-metastatic renal cell carcinoma with inferior vena cava tumor thrombus: systematic review and meta-analysis
Histopathology and outcomes of non-metastatic renal cell carcinoma with inferior vena cava tumor thrombus: systematic review and meta-analysis Open
Renal cell carcinoma (RCC) accounts for a significant portion of new cancer diagnoses, with a subset presenting with tumor thrombus in the inferior vena cava (IVC), complicating treatment and prognosis. Despite surgical intervention being …
View article: Single port robotic platform and toolbox: What is new
Single port robotic platform and toolbox: What is new Open
Introduction: The DaVinci Single Port™ (SP) system is a recent innovation in urologic surgery, initially evaluated in cadaveric models for various procedures. Following successful clinical trials and FDA approval in 2018, the system receiv…
View article: The Use of Artificial Intelligence in Urologic Oncology: Current Insights and Challenges
The Use of Artificial Intelligence in Urologic Oncology: Current Insights and Challenges Open
Artificial intelligence (AI) is increasingly influencing the field of urologic oncology, offering novel tools to support for clinical decision-making, enhance diagnostic precision, and assist in surgical and pathological workflows. Machine…
View article: Chatgpt vs traditional pedagogy: a comparative study in urological learning
Chatgpt vs traditional pedagogy: a comparative study in urological learning Open
Purpose Technological evolution is radically changing medical learning models. We evaluated the learning outcomes of urological concepts using ChatGPT, traditional lecture and combined approach. Methods We conducted a randomized triple-bli…
View article: Peyronie's disease in the United States: A real‐world, 13‐year nationwide analysis of demographics, clinical characteristics, and treatment trends
Peyronie's disease in the United States: A real‐world, 13‐year nationwide analysis of demographics, clinical characteristics, and treatment trends Open
Background Real‐world data on Peyronie's disease remains limited. Objectives Describe the demographics, clinical characteristics, and therapeutic management of Peyronie's disease patients in the United States. Materials and methods A retro…
View article: Iatrogenic Ureteropelvic Junction Disruption from Lumbar Spinal Fusion Surgery: Early Repair using The SP Robotic System.
Iatrogenic Ureteropelvic Junction Disruption from Lumbar Spinal Fusion Surgery: Early Repair using The SP Robotic System. Open
SP robotic repair of the UPJ injury is safe and feasible. This procedure provides the benefits of minimally invasive surgery, and it should be considered as a valid alternative to traditional multiport robotic approach.
View article: Holmium laser enucleation of the prostate vs single-port transvesical enucleation of the prostate: Single-center comparative surgical outcomes during early adoption
Holmium laser enucleation of the prostate vs single-port transvesical enucleation of the prostate: Single-center comparative surgical outcomes during early adoption Open
Both HoLEP and STEP can be safely implemented for the minimally invasive treatment of BPH. Each of the procedures presents some appealing features that can be tailored to different subgroups of patients. HoLEP is appealing for higher surgi…
View article: Focal Therapy for Prostate Cancer: Recent Advances and Insights
Focal Therapy for Prostate Cancer: Recent Advances and Insights Open
Focal therapy has emerged as a balanced middle ground aiming to reduce overtreatment and the risk of progression, as well as patients’ distress and anxiety. Focal therapy and partial gland ablation prioritize the precise elimination of the…
View article: PI‐RADS in Predicting csPCa: A Comparison Between Academic and Nonacademic Centers
PI‐RADS in Predicting csPCa: A Comparison Between Academic and Nonacademic Centers Open
Introduction The introduction of multiparametric prostate magnetic resonance imaging (mpMRI) has revolutionized prostate cancer (PCa) diagnosis, enhancing the localization of clinically significant prostate cancer (csPCa) and guiding targe…
View article: Single Port Robotic Nephrectomy via lower anterior retroperitoneal approach: feasible, safe and effective option in surgically complex patients
Single Port Robotic Nephrectomy via lower anterior retroperitoneal approach: feasible, safe and effective option in surgically complex patients Open
Retroperitoneal SP-RARN via the lower anterior approach avoids the peritoneal cavity, making it suitable for certain patients. In these patients, more so than in others, this procedure is feasible, safe, and less morbid than the standard m…
View article: Follow Up Care After Penile Sparing Surgery for Penile Cancer: Current Perspectives
Follow Up Care After Penile Sparing Surgery for Penile Cancer: Current Perspectives Open
Penile cancer (PeCa) is a rare urologic tumor worldwide. In 2024, 2100 new cases and 500 deaths are estimated in the United States. Radical surgery via total penectomy has historically been the cornerstone of treatment, since it provides e…
View article: Current status, evolution, and future perspectives in robotic platform systems for prostate cancer treatment: a narrative review
Current status, evolution, and future perspectives in robotic platform systems for prostate cancer treatment: a narrative review Open
This review aims to analyze the current state of the use of robotic platforms in urology, particularly in radical prostatectomy, and to understand the evolution.
View article: Advances in Molecular Mechanisms of Kidney Disease: Integrating Renal Tumorigenesis of Hereditary Cancer Syndrome
Advances in Molecular Mechanisms of Kidney Disease: Integrating Renal Tumorigenesis of Hereditary Cancer Syndrome Open
Renal cell carcinoma (RCC) comprises various histologically distinct subtypes, each characterized by specific genetic alterations, necessitating individualized management and treatment strategies for each subtype. An exhaustive search of t…
View article: Incidence, Timing, and Pattern of Atypical Recurrence after Minimally Invasive Surgery for Urothelial Carcinoma
Incidence, Timing, and Pattern of Atypical Recurrence after Minimally Invasive Surgery for Urothelial Carcinoma Open
The management of urothelial carcinoma has evolved with the introduction of minimally invasive techniques such as laparoscopic or robotic procedures, challenging the traditional approach of open surgery, and giving rise to atypical recurre…
View article: Selective clamping robotic renal enucleoresection: A step-by-step procedure
Selective clamping robotic renal enucleoresection: A step-by-step procedure Open
Objective: we aim to illustrate step by step the technique of enucleoresection of renal mass during robot-assisted partial nephrectomy (RAPN). Patient and surgical procedure: 72-year-old man affected by asymptomatic and incidental small re…
View article: Pathophysiology and Main Molecular Mechanisms of Urinary Stone Formation and Recurrence
Pathophysiology and Main Molecular Mechanisms of Urinary Stone Formation and Recurrence Open
Kidney stone disease (KSD) is one of the most common urological diseases. The incidence of kidney stones has increased dramatically in the last few decades. Kidney stones are mineral deposits in the calyces or the pelvis, free or attached …
View article: Mastering bladder paraganglioma for optimal treatment: a case report of robot-assisted surgery
Mastering bladder paraganglioma for optimal treatment: a case report of robot-assisted surgery Open
Bladder paraganglioma is a rare neuroendocrine neoplasm, either functional or non-functional, arising from the urinary bladder. Functional variants present with catecholamine-related symptoms, while non-functional variants pose diagnostic …