Amitabh Singh
YOU?
Author Swipe
View article: Pediatric tumor microenvironment: developmental dynamics and therapy resistance
Pediatric tumor microenvironment: developmental dynamics and therapy resistance Open
The tumor microenvironment (TME) in pediatric cancers is profoundly shaped by the unique biological context of childhood development. Unlike adult tumors, pediatric malignancies arise in growing tissues, where evolving immune systems, dyna…
View article: Improving outcomes in Pediatric acute lymphoblastic leukemia with a uniform multicentric protocol (ICiCLe): experience from an Indian center
Improving outcomes in Pediatric acute lymphoblastic leukemia with a uniform multicentric protocol (ICiCLe): experience from an Indian center Open
View article: Reviving Seth Chuhimal Ki Talab: Traditional Water Systems and Environmental Sustainability in Nuh, Haryana
Reviving Seth Chuhimal Ki Talab: Traditional Water Systems and Environmental Sustainability in Nuh, Haryana Open
Traditional water bodies for centuries have served as lifelines for communities in India. These water bodies not only offer vital water security but also provide ecological and cultural benefits. Seth Chuhimal ki Talab in Nuh, Haryana, is …
View article: Efficacy of Short-Course High-Dose Oral Prednisolone in Rapid Platelet Recovery for Pediatric Acute Immune Thrombocytopenic Purpura: A Prospective Cohort Study
Efficacy of Short-Course High-Dose Oral Prednisolone in Rapid Platelet Recovery for Pediatric Acute Immune Thrombocytopenic Purpura: A Prospective Cohort Study Open
The study suggests that short-course high-dose PDN can be an effective first-line therapy for acute ITP. It promotes faster platelet recovery and reduces hospitalization time with minimal adverse effects.
View article: “Unusual Presentation of Engraftment Syndrome Following Autologous Hematopoietic Stem Cell Transplant in a Nivolumab-Treated Child of relapsed classical Hodgkin lymphoma”: A Case Report.
“Unusual Presentation of Engraftment Syndrome Following Autologous Hematopoietic Stem Cell Transplant in a Nivolumab-Treated Child of relapsed classical Hodgkin lymphoma”: A Case Report. Open
View article: Triple – negative essential thrombocythemia in a child: A diagnostic challenge
Triple – negative essential thrombocythemia in a child: A diagnostic challenge Open
Background: Essential thrombocythemia (ET) is a well-defined entity that is characterized by the presence of splenomegaly, uncontrolled hematopoiesis, and is independent of control of growth factors. The annual incidence of ET in children …
View article: Managing Parahemophilia: A Rare Coagulation Disorder – Case Report and Review
Managing Parahemophilia: A Rare Coagulation Disorder – Case Report and Review Open
A 5-month-old male child was admitted with cough and fever, during which excessive bleeding occurred from a venipuncture site. Born from a third-degree consanguineous marriage, the child was developmentally normal. Routine blood tests show…
View article: Familial hemophagocytic lymphohistiocytosis type 4 (FHL4) with a rare STX11 genetic variation and leukoencephalopathy: a case report
Familial hemophagocytic lymphohistiocytosis type 4 (FHL4) with a rare STX11 genetic variation and leukoencephalopathy: a case report Open
View article: Shwachman–Diamond Syndrome: A Rare Possibility in a Child with Failure to Thrive and Recurrent Infections - A Case Report
Shwachman–Diamond Syndrome: A Rare Possibility in a Child with Failure to Thrive and Recurrent Infections - A Case Report Open
Background: Shwachman–Diamond Syndrome (SDS) is a rare inherited autosomal recessive multisystem disorder, with features of pancreatic exocrine insufficiency, skeletal malformations, immunodeficiency, and bone marrow failure having a high …
View article: Leveraging IoT for Personalized Vitamin D Management: Monitoring, Optimization and Disease Prevention
Leveraging IoT for Personalized Vitamin D Management: Monitoring, Optimization and Disease Prevention Open
Vitamin D is essential for maintaining overall well-being and plays a significant role in preventing various health conditions. However, a vast majority of the global population experiences vitamin D deficiency (VDD), affecting nearly one …
View article: Evaluating the efficacy and impact of neutropenic diet in pediatric hematology patients: a longitudinal cohort study on adherence, clinical outcomes, and socioeconomic factors
Evaluating the efficacy and impact of neutropenic diet in pediatric hematology patients: a longitudinal cohort study on adherence, clinical outcomes, and socioeconomic factors Open
Background and aim A neutropenic diet aims to reduce hospitalizations from febrile neutropenia and sepsis in pediatric hematology patients during chemotherapy. This study aimed to evaluate its effectiveness in improving mortality, morbidit…
View article: The Misleading Normal in an Unusual Case of Wiskott–Aldrich Syndrome: A Case Report with Review of Literature
The Misleading Normal in an Unusual Case of Wiskott–Aldrich Syndrome: A Case Report with Review of Literature Open
Wiskott–Aldrich syndrome (WAS) is a rare X-linked disorder characterized by thrombocytopenia, eczema, and immunodeficiency. Mutations in the WAS gene disrupt hematopoietic cell actin cytoskeletal reorganization, often leading to classic sm…
View article: Combinatory Flowcytometric Approach in Pediatric Acute Lymphoid Leukemia Identifies Surrogate Minimal Residual Disease Markers
Combinatory Flowcytometric Approach in Pediatric Acute Lymphoid Leukemia Identifies Surrogate Minimal Residual Disease Markers Open
Background/Objectives: Minimal residual disease (MRD) refers to the resistant clonal population of leukemia cells that survive induction chemotherapy, serving as a critical indicator of treatment response in pediatric Acute Lymphoid Leukem…
View article: Analysis of TCGA (The Cancer Genome Atlas) Data for Prognosis, Risk Categorization, and Survival of AML Patients Using Bioinformatics
Analysis of TCGA (The Cancer Genome Atlas) Data for Prognosis, Risk Categorization, and Survival of AML Patients Using Bioinformatics Open
Introduction Acute myeloid leukemia (AML) is a leading cause of mortality among Indian children and adults, driven by diverse genetic and epigenetic abnormalities. Limited access to genomic sequencing in India due to resource constraints h…
View article: Incidence, Risk Factors, and Outcome of Tumor Lysis Syndrome in Hospitalized Children (1–12 Years) with Malignancy
Incidence, Risk Factors, and Outcome of Tumor Lysis Syndrome in Hospitalized Children (1–12 Years) with Malignancy Open
Introduction Oncological emergencies such as tumor lysis syndrome (TLS) can strike before or during the start of chemotherapy. TLS is an important cause of death in children with malignancies. Understanding the risk factors and timely mana…
View article: Formulation and Evaluation of Herbal Cream Using Aegle Marmelos Essential Oil
Formulation and Evaluation of Herbal Cream Using Aegle Marmelos Essential Oil Open
This study aimed to formulate and evaluate an herbal cream utilizing the essential oil extracted from Aegle marmelos (bael) leaves. Aegle marmelos is a medicinally significant plant with a rich history in traditional medicine, known for it…
View article: Clinical, cyto-molecular spectrum and outcomes of myeloid sarcoma in children
Clinical, cyto-molecular spectrum and outcomes of myeloid sarcoma in children Open
View article: Improving the outcome of pediatric ALL by transitioning from nonuniform chemotherapy regimens to a uniform multicentric protocol: A comprehensive experience from an Indian center on the ICiCLe protocol
Improving the outcome of pediatric ALL by transitioning from nonuniform chemotherapy regimens to a uniform multicentric protocol: A comprehensive experience from an Indian center on the ICiCLe protocol Open
View article: KDM6A: An Emerging Biomarker for Prediction of Treatment Response and Relapse in Pediatric Acute Myeloid Leukemia
KDM6A: An Emerging Biomarker for Prediction of Treatment Response and Relapse in Pediatric Acute Myeloid Leukemia Open
View article: The Indian Childhood Cancer Survivorship (C2S) Study: Making Of The Indian Childhood Cancer Survivorship Registry & Cohort; An INPHOG Study
The Indian Childhood Cancer Survivorship (C2S) Study: Making Of The Indian Childhood Cancer Survivorship Registry & Cohort; An INPHOG Study Open
View article: Persistent Generalized Lymphadenopathy: A Diagnostic Conundrum—Case Report and Review of Literature
Persistent Generalized Lymphadenopathy: A Diagnostic Conundrum—Case Report and Review of Literature Open
Generalized lymphadenopathy is a nonspecific sign with heterogenous etiology including infective, inflammatory, and malignant causes. We present the case of a child who presented with generalized lymphadenopathy, involving the cervical, ax…
View article: VE76 Emergency robotic exploration for obstructed parastomal hernia post robotic radical cystectomy with ileal conduit - our initial experience, tips and tricks
VE76 Emergency robotic exploration for obstructed parastomal hernia post robotic radical cystectomy with ileal conduit - our initial experience, tips and tricks Open
View article: VJY07 Robot-assisted partial nephrectomy for a renal cell carcinoma in a horseshoe kidney–video based illustration
VJY07 Robot-assisted partial nephrectomy for a renal cell carcinoma in a horseshoe kidney–video based illustration Open
View article: Duodenal obstruction: A rare complication of langerhans cell histiocytosis
Duodenal obstruction: A rare complication of langerhans cell histiocytosis Open
Background: Langerhans cell histiocytosis (LCH) has a variable presentation. Gastrointestinal involvement is rare and portends a poor prognosis in LCH. Case report: Herein, we describe the presentation, progression, management, and outcome…
View article: Comparative Study of Shatpuspa Tail Matra Basti with Dasmool Tail Matra Basti in Anartav W.S.R. to Vata Kaphaj Aartav Dusti (PCOS)
Comparative Study of Shatpuspa Tail Matra Basti with Dasmool Tail Matra Basti in Anartav W.S.R. to Vata Kaphaj Aartav Dusti (PCOS) Open
Women’s health is always being prime concern for medical fraternity since female not only serve for her family but also support society and nation. The current scenario witnessed rise in female health issues due to the stressful pattern of…
View article: The impact of COVID-19 pandemic on access to treatment for children with cancer in India and treating centre practices: Results of the InPOG-ACC-20-04 study
The impact of COVID-19 pandemic on access to treatment for children with cancer in India and treating centre practices: Results of the InPOG-ACC-20-04 study Open
Background The COVID-19 pandemic had led the Indian government to announce a nationwide lockdown on the 23rd of March 2020. This study (InPOG-ACC-20-04) aimed to explore the impact of this on the accessibility of care of children with canc…
View article: Early prognosis prediction in acute myeloid and acute lymphoid leukemia patients using cell-free DNA concentration ratios
Early prognosis prediction in acute myeloid and acute lymphoid leukemia patients using cell-free DNA concentration ratios Open
Background: Cell-free DNA (cfDNA) is a promising biomarker for disease prediction in many cancers, including acute leukemia (acute myeloid leukemia [AML] and acute lymphoblastic leukemia [ALL]). This study investigated the role of cfDNA in…
View article: Clinical, cyto-molecular spectrum and outcomes of myeloid sarcoma in children
Clinical, cyto-molecular spectrum and outcomes of myeloid sarcoma in children Open
View article: The INPHOG childhood cancer survivorship (C2S) study: Making of the Indian childhood cancer survivorship cohort
The INPHOG childhood cancer survivorship (C2S) study: Making of the Indian childhood cancer survivorship cohort Open
View article: Assessment of Carbon Stock in Response to Varied Land Use Systems and Soil Depths in Chandel District, Manipur, India
Assessment of Carbon Stock in Response to Varied Land Use Systems and Soil Depths in Chandel District, Manipur, India Open
To understand the effects of land use system and its cropping techniques, the study on carbon stock and soil nutrients in response to varied land use systems and soil depths in Chandel district was carried out during 2020 from five differe…