Explanipedia

Tolvaptan versus other interventions for hyponatraemia in people with cirrhosis Open

K N Anila, N Saraswathy, Zubair Umer Mohamed, Christi Titus Varghese, ST Binoj , et al. · 2025

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To evaluate the benefits and harms of tolvaptan versus standard medical management, placebo, or other vaptans for the treatment of hyponatraemia in peo…

FXR agonist in post-liver transplantation patients: a randomized open-labeled study. Open

K N Anila, Saraswathy S. Nair, D. Balakrishnan, G. Unnikrishnan, ST Binoj , et al. · 2025

Liver diseases cause nearly 2 million deaths worldwide each year, with approximately 1 million deaths from cirrhosis complications and another 1 million from viral hepatitis and liver cancer, according to WHO estimates. Liver transplantati…

FXR agonist in post-liver transplantation patients: a randomized open-labeled study. Open

K N Anila, Saraswathy S. Nair, D. Balakrishnan, G. Unnikrishnan, ST Binoj , et al. · 2025

Liver diseases cause nearly 2 million deaths worldwide each year, with approximately 1 million deaths from cirrhosis complications and another 1 million from viral hepatitis and liver cancer, according to WHO estimates. Liver transplantati…

Prosthetic Graft Migration in Living Donor Liver Transplantation: A Case for Conservative Management? Open

Saraswathy Sivaprasadan, K N Anila, Jancy Koneti, S Sudhindran · 2024

A 61-year-old male underwent living donor liver transplantation (LDLT) for decompensated chronic liver disease with hepatocellular carcinoma. The right lobe from the live donor was used as the graft. During implantation, the drainage of th…

Sample size calculation Open

S Saraswathy, K N Anila, S Sudhindran, Arun Valsan · 2023

Introduction Sample size is defined as the number of experimental units needed for a study. The required sample size of a study is determined by the distribution and type of data. The determination of sample size aids a researcher in estim…

Survival analysis: A primer Open

K N Anila, Sivaprasadan Saraswathy, Surendran Sudhindran, Arun Valsan · 2023

Survival analysis is an important time-bound statistical tool used in medical research to gather valuable insights into outcomes, treatment efficacy, and disease progression. This tool employs various models to run the data such as Cox pro…

Immunosuppression in Liver Transplant Recipients in the Setting of Sepsis Open

Shweta Mallick, K N Anila, Saraswathy Sivaprasadan, S Sudhindran · 2022

Short Review On Varicose Vein And Its Management Open

N. Giri Pranav, K N Anila, Riju.R.Menon · 2021

A varicose vein is a condition which affects a large number of people in Western countries and India especially, the northern areas. For curing this proper disease diagnosis, sufficient care for patient and treatment strategies are require…

Management of a Pregnant Patient with Platelet Type Von Willebrand Disorder: Case Report and Review of Literature Open

Merin Dana, Sidharthan Neeraj, K VKarthika, Manoj Unni, G Rema , et al. · 2021

Introduction: Platelet type Von Willebrand disorder(PT -VWD) is an autosomal bleeding syndrome induced by an irregular glycoprotein Ib protein function that results in platelets that are hyperresponsive.While this condition seems to be wel…

Amoxycillin and clavulanic acid-induced Stevens-Johnson Syndrome in a dialysis patient Open

Aarcha Komalath Ajayan, K N Anila, Dipu T Sathyapalan · 2020

A 48-year-old male patient with chronic kidney disease on haemodialysis came with complaints of worsening fever comprising maculopapular rashes and was diagnosed with Stevens-Johnson Syndrome- Toxic Epidermal Necrolysis (SJS-TEN) with seps…

Assessment of safety and effectiveness of oral morphine on patients attending pain and palliative care: a study on Indian population Open

Sreelakshmi Jayan, Stephy Stephen, Kevin Tom Koshy, Nikhil John Abraham, Sunitha Daniel , et al. · 2020

Opioid analgesics remain the corner stone of effective management of moderate to severe pain. Morphine in its oral and parenteral form is one of the most affordable options left to treat severe cancer pain in most Palliative centres in Ind…

A study on the assessment of clinical profile and treatment pattern of multiple sclerosis in a tertiary care hospital Open

N. Amrutha, Preet Anand, K. R. Swathy, K N Anila, Suresh R. Kumar · 2020

Multiple sclerosis is the most common chronic autoimmune neurodegenerative disorder of the Central Nervous System (CNS), which occurs due to the destruction in myelin sheath of the nerve fibres. AIM: To study the clinical profile and treat…

NAPROXEN INDUCED ERYTHEMA MULTIFORME-A RARE CASE REPORT Open

Sai Keerthana P. C., K N Anila, Reshma Reji · 2017

Erythema multiforme (EM) is a hypersensitivity reaction characterized by varying degrees of blisters and ulcerations. We report a case of 4 y old girl child born for Non-custodial parents who has a history of seizures and a known case of c…

Methotrexate Induced Lung Toxicity-A Case Report Open

Seetha Lekshmi, Remya Antony, Neeraj Sidharthan, Gireesh Kammath, K N Anila · 2017

Methotrexate (MTX) belongs to a class of antimetabolites. It may cause serious side effects like lung problems, lung infections. Methotrexate-induced lung disease, as well as acute or chronic interstitial pneumonitis, is a potentially risk…

CARBAMAZEPINE INDUCED SLE-A RARE AND SERIOUS ADR Open

Sai Keerthana P. C., K N Anila · 2016

Carbamazepine is a commonly used antiseizure medication. Carbamazepine-induced SLE (Systemic Lupus Erythematosus) is a very rare phenomenon. Drug-induced SLE is an autoimmune disease caused by long-term use of certain drugs. Carbamazepine …

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