Explanipedia

Analysis of Genetic and MRI Changes, Blood Markers, and Risk Factors in a Twin Pair Discordant of Progressive Supranuclear Palsy Open

Alíz Persely, Beatrix Beszedics, Krisztina Pálóczi, Márton Piroska, Amirreza Alijanpourotaghsara , et al. · 2023

Background and Objectives: Progressive supranuclear palsy (PSP) is a neurodegenerative disease, a tauopathy, which results in a wide clinical spectrum of neurological symptoms. The diagnosis is mostly based on clinical signs and neuroimagi…

Parapharyngeal Fat Tissue Accumulation and Its Association with Carotid Intima-Media Thickness in Discordant Twin Pairs Open

Zsófia Jokkel, Marcell Szily, Márton Piroska, Helga Szabó, Anita Hernyes , et al. · 2023

Background: Recurrent upper airway obstruction during sleep is a common feature of obstructive sleep apnea (OSA). Risk factors for the development of OSA include obesity, male gender and smoking. In addition, anatomical factors contribute …

Heritability of Subcortical Grey Matter Structures Open

David Strelnikov, Amirreza Alijanpourotaghsara, Márton Piroska, Laszlo Szalontai, Bianka Forgó , et al. · 2022

Background and Objectives: Subcortical grey matter structures play essential roles in cognitive, affective, social, and motoric functions in humans. Their volume changes with age, and decreased volumes have been linked with many neuropsych…

The Relationship between Atherosclerosis and Gut Microbiome in Patients with Obstructive Sleep Apnoea Open

Helga Szabó, Márton Piroska, Anita Hernyes, Luca Zoldi, János Juhász , et al. · 2022

Background: Obstructive sleep apnoea (OSA) and gut dysbiosis are known risk factors for atherosclerosis. However, only very few studies have been focused on the relationship between OSA, atherosclerosis, and the intestinal microbiome, all …

Genetic and Environmental Effects on the Development of White Matter Hyperintensities in a Middle Age Twin Population Open

Amirreza Alijanpourotaghsara, David Strelnikov, Márton Piroska, Laszlo Szalontai, Bianka Forgó , et al. · 2022

Introduction: White matter hyperintensities (WMH) indicate white matter brain lesions in magnetic resonance imaging (MRI), which can be used as a marker for brain aging and cerebrovascular and neurodegenerative disorders. Twin studies reve…

Overlapping Genetic Background of Coronary Artery and Carotid/Femoral Atherosclerotic Calcification Open

Anita Hernyes, Márton Piroska, Bence Fejér, Laszlo Szalontai, Helga Szabó , et al. · 2021

Background and objectives: Multivessel atherosclerosis and its genetic background are under-investigated, although atherosclerosis is seldom local and still causes high mortality. Alternative methods to assess coronary calcification (CAC) …

Association between Gut Microbial Diversity and Carotid Intima-Media Thickness Open

Helga Szabó, Anita Hernyes, Márton Piroska, Balázs Ligeti, Peter Fussy , et al. · 2021

Background and Objectives: There is an increasing focus on the effect of the gut microbiome on developing atherosclerosis, but there is still no unified standpoint. We aimed to find associations between intestinal microbiome diversity and …

Association between personality profile and subclinical atherosclerosis: The role of genes and environment Open

Emanuela Medda, Corrado Fagnani, Guido Alessandri, Claudio Baracchini, Anita Hernyes , et al. · 2020

P121 Background of the Development of Carotid and Femoral Atherosclerotic Plaques in Twins Open

Dávid László Tárnoki, Helga Szabó, Kata Gyulay, Zsófia Jokkel, Rebeka Debreceni , et al. · 2020

P30 Interplay of Genetic and Environmental Factors Determining Carotid and Femoral Intima-media Thickness and Plaques Open

Ádám Domonkos Tárnoki, Rebeka Debreceni, Greta Janositz, Kata Gyulay, Zsófia Jokkel , et al. · 2019

P121 Background of the Development of Carotid and Femoral Atherosclerotic Plaques in Twins Open

Dávid László Tárnoki, Helga Szabó, Kata Gyulay, Zsófia Jokkel, Rebeka Debreceni , et al. · 2019

Introduction Development of carotid and femoral atherosclerotic plaques proved to be heritable in previous studies. However, no comprehensive ultrasonographic evaluation of the volume and types of plaque has been performed. Methods Compreh…

Genetic and environmental factors on heart rate, mean arterial pressure and carotid intima–media thickness: A longitudinal twin study Open

Ádám Domonkos Tárnoki, Laszlo Szalontai, Corrado Fagnani, Dávid László Tárnoki, Pierleone Lucatelli , et al. · 2019

Genetic factors have a substantial role in the longitudinal change of HR, MAP and cIMT; however, the influence of unique environmental factors remains relevant. Further studies should better elucidate whether epigenetic mechanisms have a r…

Are the Variants of the Circle of Willis Determined by Genetic or Environmental Factors? Results of a Twin Study and Review of the Literature Open

Bianka Forgó, Ádám Domonkos Tárnoki, Dávid László Tárnoki, Dániel Kovács, Laszlo Szalontai , et al. · 2018

Background: Anatomic variants of the circle of Willis (CW) are commonly observed in healthy subjects. Genetic and environmental factors influencing these variants remain unclear. Our aim was to assess the genetic and environmental backgrou…

Carotid Artery Atherosclerosis: A Review on Heritability and Genetics Open

Bianka Forgó, Emanuela Medda, Anita Hernyes, Laszlo Szalontai, Dávid László Tárnoki , et al. · 2018

Carotid atherosclerosis (CAS) is associated with increased cardiovascular risk, and therefore, assessing the genetic versus environmental background of CAS traits is of key importance. Carotid intima-media-thickness and plaque characterist…

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