Anita Kovács
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View article: Comparative Study of Dexamethasone-Loaded Thermoresponsive In Situ Gels and Polymeric Micelles for Ocular Drug Delivery
Comparative Study of Dexamethasone-Loaded Thermoresponsive In Situ Gels and Polymeric Micelles for Ocular Drug Delivery Open
Effective ocular drug delivery is still a challenge for pharmaceutical technologists due to the complex elimination mechanisms of the eye. In situ gels and polymeric micelles are among the pharmaceutical technologies that may enable us to …
View article: Hydrogel–Nanolipid Formulations for the Complex Anti-Inflammatory and Antimicrobial Therapy of Periodontitis
Hydrogel–Nanolipid Formulations for the Complex Anti-Inflammatory and Antimicrobial Therapy of Periodontitis Open
Objectives: This study aimed to develop and evaluate nanostructured lipid carriers (NLCs) loaded with meloxicam (Melox) and a therapeutic antibacterial and anti-inflammatory liquid lipid, clove oil (CO) for periodontitis treatment, a compl…
View article: The Role of Natural Deep Eutectic Solvents in a Hydrogel Formulation Containing Lidocaine
The Role of Natural Deep Eutectic Solvents in a Hydrogel Formulation Containing Lidocaine Open
Background/Objectives: This study investigates the use of natural deep eutectic solvents (NADESs) in enhancing the solubility and skin permeation of a lidocaine base, a lipophilic form, in hydrogel systems. The aim was to develop an enviro…
View article: Smart biomaterial gels for periodontal therapy: A novel approach
Smart biomaterial gels for periodontal therapy: A novel approach Open
View article: The effect of mucoadhesive polymers on ocular permeation of thermoresponsive in situ gel containing dexamethasone–cyclodextrin complex
The effect of mucoadhesive polymers on ocular permeation of thermoresponsive in situ gel containing dexamethasone–cyclodextrin complex Open
View article: Developments in Alloplastic Bone Grafts and Barrier Membrane Biomaterials for Periodontal Guided Tissue and Bone Regeneration Therapy
Developments in Alloplastic Bone Grafts and Barrier Membrane Biomaterials for Periodontal Guided Tissue and Bone Regeneration Therapy Open
Periodontitis is a serious form of oral gum inflammation with recession of gingival soft tissue, destruction of the periodontal ligament, and absorption of alveolar bone. Management of periodontal tissue and bone destruction, along with th…
View article: Improvement of lidocaine skin permeation by using passive and active enhancer methods
Improvement of lidocaine skin permeation by using passive and active enhancer methods Open
View article: An Analytical Target Profile for the Development of an In Vitro Release Test Method and Apparatus Selection in the Case of Semisolid Topical Formulations
An Analytical Target Profile for the Development of an In Vitro Release Test Method and Apparatus Selection in the Case of Semisolid Topical Formulations Open
This study focuses on how to define an Analytical Target Profile (ATP) which is intended for use in practice and on facilitating the selection of in vitro release test (IVRT) technology for diclofenac sodium topical hydrogel and cream. The…
View article: Foams Set a New Pace for the Release of Diclofenac Sodium
Foams Set a New Pace for the Release of Diclofenac Sodium Open
Medicated foams have emerged as promising alternatives to traditional carrier systems in pharmaceutical research. Their rapid and convenient application allows for effective treatment of extensive or hirsute areas, as well as sensitive or …
View article: D-dimer levels to exclude pulmonary embolism and reduce the need for CT angiography in COVID-19 in an outpatient population
D-dimer levels to exclude pulmonary embolism and reduce the need for CT angiography in COVID-19 in an outpatient population Open
Objectives Emerging results indicate that, in COVID-19, thromboembolic complications contribute to the high mortality and morbidity. Previous research showed that the prevalence of pulmonary embolism (PE) is between 25–50% in COVID-19 pati…
View article: Advancements in formulation and investigation of innovative foam-based in situ film-forming systems
Advancements in formulation and investigation of innovative foam-based in situ film-forming systems Open
View article: Formulation and investigation of hydrogels containing an increased level of diclofenac sodium using risk assessment tools
Formulation and investigation of hydrogels containing an increased level of diclofenac sodium using risk assessment tools Open
View article: HUNCHEST-II contributes to a shift to earlier-stage lung cancer detection: final results of a nationwide screening program
HUNCHEST-II contributes to a shift to earlier-stage lung cancer detection: final results of a nationwide screening program Open
View article: Lipid Nanoparticles: An Effective Tool to Improve the Bioavailability of Nutraceuticals
Lipid Nanoparticles: An Effective Tool to Improve the Bioavailability of Nutraceuticals Open
Nano-range bioactive colloidal carrier systems are envisaged to overcome the challenges associated with treatments of numerous diseases. Lipid nanoparticles (LNPs), one of the extensively investigated drug delivery systems, not only improv…
View article: Factorial design of in situ gelling two-compartment systems containing chlorhexidine for the treatment of periodontitis
Factorial design of in situ gelling two-compartment systems containing chlorhexidine for the treatment of periodontitis Open
View article: Development and evaluation of stable hydrogel formulations with enhanced diclofenac sodium concentration for effective topical drug delivery
Development and evaluation of stable hydrogel formulations with enhanced diclofenac sodium concentration for effective topical drug delivery Open
View article: Combined Nanofibrous Face Mask: Co-Formulation of Lipases and Antibiotic Agent by Electrospinning Technique
Combined Nanofibrous Face Mask: Co-Formulation of Lipases and Antibiotic Agent by Electrospinning Technique Open
The application of enzyme-based therapies has received significant attention in modern drug development. Lipases are one of the most versatile enzymes that can be used as therapeutic agents in basic skin care and medical treatment related …
View article: Prolonged activity of the transposase helper may raise safety concerns during DNA transposon-based gene therapy
Prolonged activity of the transposase helper may raise safety concerns during DNA transposon-based gene therapy Open
View article: Influence of polymers and active substances on foam stability
Influence of polymers and active substances on foam stability Open
Foams are becoming increasingly attractive delivery systems in the field of dermatology due to their beneficial properties, such as easy spreading, pleasant skin sensation, and applicability in certain skin conditions.Because of its applic…
View article: Design and Optimization of In Situ Gelling Mucoadhesive Eye Drops Containing Dexamethasone
Design and Optimization of In Situ Gelling Mucoadhesive Eye Drops Containing Dexamethasone Open
Poor bioavailability of eye drops is a well-known issue, which can be improved by increasing the residence time on the eye surface and the penetration of the active pharmaceutical ingredient (API). This study aims to formulate in situ gell…
View article: Application of Xanthan Gum and Hyaluronic Acid as Dermal Foam Stabilizers
Application of Xanthan Gum and Hyaluronic Acid as Dermal Foam Stabilizers Open
Foams are increasingly popular in the field of dermatology due to their many advantages such as easy spreading, good skin sensation, and applicability in special skin conditions. One of the critical points of foam formulation is the choice…
View article: Analytical Quality by Design (AQbD) Approach to the Development of In Vitro Release Test for Topical Hydrogel
Analytical Quality by Design (AQbD) Approach to the Development of In Vitro Release Test for Topical Hydrogel Open
The aim of our study was to adapt the analytical quality by design (AQbD) approach to design an effective in vitro release test method using USP apparatus IV with a semi-solid adapter (SSA) for diclofenac sodium hydrogel. The analytical ta…
View article: Investigation of the effect of polymers on dermal foam properties using the QbD approach
Investigation of the effect of polymers on dermal foam properties using the QbD approach Open
Dermal foams are promising drug delivery systems due to their many advantages and ease of application. Foams are also considered a novelty in the field of dermatology. In particular, they are beneficial for the treatment of skin conditions…
View article: The effect of non-invasive dermal electroporation on skin barrier function and skin permeation in combination with different dermal formulations
The effect of non-invasive dermal electroporation on skin barrier function and skin permeation in combination with different dermal formulations Open
View article: The effects of chemical permeation enhancer glycols on the skin
The effects of chemical permeation enhancer glycols on the skin Open
View article: Analytical Quality by Design (AQbD) approach to the development of in vitro release test for topical hydrogel
Analytical Quality by Design (AQbD) approach to the development of in vitro release test for topical hydrogel Open
View article: IV. Symposium of Young Researchers on Pharmaceutical Technology, Biotechnology and Regulatory Science
IV. Symposium of Young Researchers on Pharmaceutical Technology, Biotechnology and Regulatory Science Open
Design and optimization of dexamethasone containing
View article: Formulation and investigation of the effect of polymers on dermal foam properties using the QbD approach
Formulation and investigation of the effect of polymers on dermal foam properties using the QbD approach Open
View article: Comparison of Synthetic Membranes to Heat-Separated Human Epidermis in Skin Permeation Studies In Vitro
Comparison of Synthetic Membranes to Heat-Separated Human Epidermis in Skin Permeation Studies In Vitro Open
In recent years, the study of dermal preparations has received increased attention. There are more and more modern approaches to evaluate transdermal formulations, which are crucial in proving the efficacy of a formulation. The aim of this…
View article: Investigation of foams for topical use
Investigation of foams for topical use Open