Anjui Wu
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View article: Accidentals of the DNA Symphony
Accidentals of the DNA Symphony Open
Cancer epigenome profiling such as DNA methylation (5mC) and DNA hydroxymethylation (5hmC) is emerging as a sensitive approach for cancer detection and risk stratification. 5mC modification has been widely described in many cancer types in…
View article: Blood-based liquid biopsies for prostate cancer: clinical opportunities and challenges
Blood-based liquid biopsies for prostate cancer: clinical opportunities and challenges Open
Liquid biopsy has been established as a powerful, minimally invasive, tool to detect clinically actionable aberrations across numerous cancer types in real-time. With the development of new therapeutic agents in prostate cancer (PC) includ…
View article: Systemic Anti-Cancer Therapy and Metastatic Cancer Are Independent Mortality Risk Factors during Two UK Waves of the COVID-19 Pandemic at University College London Hospital
Systemic Anti-Cancer Therapy and Metastatic Cancer Are Independent Mortality Risk Factors during Two UK Waves of the COVID-19 Pandemic at University College London Hospital Open
An increased mortality risk was observed in patients with cancer during the first wave of COVID-19. Here, we describe determinants of mortality in patients with solid cancer comparing the first and second waves of COVID-19. A retrospective…
View article: Specialist palliative and end-of-life care for patients with cancer and SARS-CoV-2 infection: a European perspective
Specialist palliative and end-of-life care for patients with cancer and SARS-CoV-2 infection: a European perspective Open
Background:Specialist palliative care team (SPCT) involvement has been shown to improve symptom control and end-of-life care for patients with cancer, but little is known as to how these have been impacted by the COVID-19 pandemic. Here, w…
View article: Specialist palliative and end-of-life care for patients with cancer and SARS-CoV-2 infection: a European perspective
Specialist palliative and end-of-life care for patients with cancer and SARS-CoV-2 infection: a European perspective Open
Background: Specialist palliative care team (SPCT) involvement has been shown to improve symptom control and end-of-life care for patients with cancer, but little is known as to how these have been impacted by the COVID-19 pandemic. Here, …
View article: Cancer History and Systemic Anti-Cancer Therapy Independently Predict COVID-19 Mortality: A UK Tertiary Hospital Experience
Cancer History and Systemic Anti-Cancer Therapy Independently Predict COVID-19 Mortality: A UK Tertiary Hospital Experience Open
Background The COVID-19 pandemic remains a pressing concern to patients with cancer as countries enter the second peak of the pandemic and beyond. It remains unclear whether cancer and its treatment contribute an independent risk for morta…
View article: Genome-wide plasma DNA methylation features of metastatic prostate cancer
Genome-wide plasma DNA methylation features of metastatic prostate cancer Open
Tumor DNA circulates in the plasma of cancer patients admixed with DNA from noncancerous cells. The genomic landscape of plasma DNA has been characterized in metastatic castration-resistant prostate cancer (mCRPC) but the plasma methylome …
View article: Plasma DNA Analysis in Prostate Cancer: Opportunities for Improving Clinical Management
Plasma DNA Analysis in Prostate Cancer: Opportunities for Improving Clinical Management Open
BACKGROUND Molecular characterization of tumors could be important for clinical management. Plasma DNA obtained noninvasively as a liquid biopsy could be widely applicable for clinical implementation in biomarker-based treatment strategies…