Amr E. Ahmed
YOU?
Author Swipe
View article: The association between APOA1 (rs5069) gene polymorphism and insulin resistance surrogates and metabolic indices among obese individuals with different glycemic statuses (euglycemic and T2DM)
The association between APOA1 (rs5069) gene polymorphism and insulin resistance surrogates and metabolic indices among obese individuals with different glycemic statuses (euglycemic and T2DM) Open
Obesity significantly contributes to insulin resistance and type 2 mellitus diabetes (T2DM), with both environmental and genetic factors influencing metabolic risk. Apolipoprotein A1 (APOA1), a key regulator of lipid metabolism, has geneti…
View article: Assessing the Societal Impact of Public Road Projects Using the Battelle Method: An Ex-Post Cost-Benefit Analysis in Nasarawa State, Nigeria
Assessing the Societal Impact of Public Road Projects Using the Battelle Method: An Ex-Post Cost-Benefit Analysis in Nasarawa State, Nigeria Open
Ex-post Cost-Benefit Analysis (CBA) is an essential instrument that aids in assessing the worthwhileness of an ongoing or completed project in order to forestall the reoccurrence of low positive impact or detrimental projects in the future…
View article: Impact of Micro-RNAs as biomarkers for end-stage renal disease related to hypertension and diabetes
Impact of Micro-RNAs as biomarkers for end-stage renal disease related to hypertension and diabetes Open
End-stage renal disease (ESRD) is a rapidly increasing global health and healthcare challenge. MicroRNAs (miRNAs) have been implicated in kidney disease due to their role in apoptosis, cell proliferation, differentiation, and development. …
View article: Knowledge About Familial Mediterranean Fever: A Literature Review
Knowledge About Familial Mediterranean Fever: A Literature Review Open
Familial Mediterranean fever (FMF) is an uncommon genetic fault that results in persistent episodes of fever and inflammation in various parts of the body. FMF is caused by mutations in the MEFV gene, which codes for the inflammation-regul…
View article: Chitosan nano-formulation enhances stability and bactericidal activity of the lytic phage HK6
Chitosan nano-formulation enhances stability and bactericidal activity of the lytic phage HK6 Open
Background Successful treatment of pathogenic bacteria like Enterobacter Cloacae with bacteriophage (phage) counteract some hindrance such as phage stability and immunological clearance. Our research is focused on the encapsulation of phag…
View article: Characterization and genomic analysis of the lytic bacteriophage vB_EclM_HK6 as a potential approach to biocontrol the spread of Enterobacter cloacae contaminating food
Characterization and genomic analysis of the lytic bacteriophage vB_EclM_HK6 as a potential approach to biocontrol the spread of Enterobacter cloacae contaminating food Open
Background Increased prevalence of Enterobacter cloacae within food products underscores food as an underexplored reservoir for antibiotic resistance, thus requiring particular intervention. Bacteriophages have been explored as a promising…
View article: Potential protective association of the AA genotype and a allele of CXCR4 rs2228014 polymorphism with COVID-19 severity in adult egyptians
Potential protective association of the AA genotype and a allele of CXCR4 rs2228014 polymorphism with COVID-19 severity in adult egyptians Open
Background By the end of December 2019, a new coronavirus, termed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged, and the cause of the disease was named coronavirus disease 2019 (COVID-19). Several genetic factors ha…
View article: Case-control study: Unveiling human polyomaviruses and papillomavirus in Egyptian colorectal cancer patients
Case-control study: Unveiling human polyomaviruses and papillomavirus in Egyptian colorectal cancer patients Open
Background Colorectal cancer (CRC) is a cancer type that is thought to be influenced by human papillomaviruses (HPVs) and human polyomaviruses (HPyVs). In Egypt, CRC ranks as the 7th most common cancer, accounting for 3.47% of male cancers…
View article: The implication of miR-200a and miR-132 expression and their correlations with NF-κB/TNF-alpha signaling in adults with diabetic nephropathy
The implication of miR-200a and miR-132 expression and their correlations with NF-κB/TNF-alpha signaling in adults with diabetic nephropathy Open
MiR-200a as well as miR-132 expression levels, and their correlations with NF-κB/TNF-alpha signaling, were able to differentiate between DN patients with lower eGFR, suggesting their utility as diagnostic and prognostic biomarkers.
View article: Association of microRNA-192, pentraxin-3, and transforming growth factor-beta1 with estimated glomerular filtration rate in adults with diabetic nephropathy
Association of microRNA-192, pentraxin-3, and transforming growth factor-beta1 with estimated glomerular filtration rate in adults with diabetic nephropathy Open
Objective Nephropathy is among the most pervasive complications of diabetes; it frequently results in end-stage renal disease and even death. However, current biomarkers for diabetic nephropathy (DN) have limited diagnostic utility. Thus, …
View article: parazitCUB: An R package to streamline the process of investigating the adaptations of parasites' codon usage bias
parazitCUB: An R package to streamline the process of investigating the adaptations of parasites' codon usage bias Open
Examining the intricate association between parasites and their hosts, particularly at the codon level, assumes paramount importance in comprehending evolutionary processes and forecasting the characteristics of novel parasites. While dive…
View article: Genetic clues to COVID-19 severity: exploring the stromal cell-derived factor-1/CXCL12 rs2839693 polymorphism in adult Egyptians
Genetic clues to COVID-19 severity: exploring the stromal cell-derived factor-1/CXCL12 rs2839693 polymorphism in adult Egyptians Open
Background A novel corona virus called SARS-CoV-2 was identified at the end of December 2019, and the illness induced by it was designated as coronavirus disease 2019 (COVID-19). Severity of the disease could vary significantly since most …
View article: Some genetic differences in patients with rheumatoid arthritis
Some genetic differences in patients with rheumatoid arthritis Open
Objective Vitamin D is important for bone and cartilage metabolism. Changes in vitamin D blood level may be related to pathological disorders such as rheumatoid arthritis (RA). The main aim of this study is to investigate the association b…
View article: Relation between Cytokine Levels and Pulmonary Dysfunction in COVID-19 Patients: A Case-Control Study
Relation between Cytokine Levels and Pulmonary Dysfunction in COVID-19 Patients: A Case-Control Study Open
Aim: The study aimed to assess the relationships between serum cytokine levels and pulmonary dysfunctions in individuals with COVID-19. These correlations may help to suggest strategies for prevention and therapies of coronavirus disease. …
View article: Relation between Cytokines Expression and Pulmonary Dysfunction among a Cohort of COVID-19 Patients
Relation between Cytokines Expression and Pulmonary Dysfunction among a Cohort of COVID-19 Patients Open
Aim: In individuals with COVID-19, the study assessed the relationship between cytokine expression and pulmonary dysfunction. These correlations may help to suggest strategies for prevention and therapies of coronavirus disease outbreak. P…
View article: Correlations between Cytokine Levels, Liver Function Markers, and Neuropilin-1 Expression in Patients with COVID-19
Correlations between Cytokine Levels, Liver Function Markers, and Neuropilin-1 Expression in Patients with COVID-19 Open
Aim: The study evaluated the correlations between cytokine levels, liver function markers, and neuropilin-1 (NRP-1) expression in patients with COVID-19 in Egypt. The study also aimed to evaluate the accuracy sensitivity, specificity, and …
View article: Clinical Laboratory Features of Moderate and Severe Patients with COVID-19 among a Cohort of Egyptian Population
Clinical Laboratory Features of Moderate and Severe Patients with COVID-19 among a Cohort of Egyptian Population Open
Aim: The study aimed to evaluate the clinical laboratory features of moderate and severe COVID-19 patients among a cohort of the Egyptian population. The study also aimed to assess the accuracy—sensitivity, specificity, and area unde…
View article: Association between Liver Function Indicators, Immunoglobulins, and Toll-like Receptors and Neuropilin-1 Expression in Patients with COVID-19
Association between Liver Function Indicators, Immunoglobulins, and Toll-like Receptors and Neuropilin-1 Expression in Patients with COVID-19 Open
Purpose: The study aimed to investigate if there were any links between liver function biomarkers and immunoglobulins levels in serum, and Toll-like receptors (TLRs) and neuropilin-1 (NRP1) in COVID-19 patients. The study also aimed to ass…
View article: Association between liver function indicators, immunoglobulins, and Toll-like receptors and neuropilin-1 expression in patients with COVID-19
Association between liver function indicators, immunoglobulins, and Toll-like receptors and neuropilin-1 expression in patients with COVID-19 Open
Purpose: The study aimed to investigate if there were any links between liver function biomarkers and immunoglobulins levels in serum, and Toll-like receptors (TLRs) and neuropilin-1 (NRP1) in COVID-19 patients. The study also aimed to ass…