Anke Bernstein
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View article: The Effect of Collagen-I Coatings of 3D Printed PCL Scaffolds for Bone Replacement on Three Different Cell Types
The Effect of Collagen-I Coatings of 3D Printed PCL Scaffolds for Bone Replacement on Three Different Cell Types Open
Introduction The use of scaffolds in tissue engineering is becoming increasingly important as solutions need to be found to preserve human tissues such as bone or cartilage. Various factors, including cells, biomaterials, cell and tissue c…
View article: A Method for the Evaluation of Early Osseointegration of Implant Materials Ex Vivo: Human Bone Organ Model
A Method for the Evaluation of Early Osseointegration of Implant Materials Ex Vivo: Human Bone Organ Model Open
In the present work, an ex vivo organ model using human bone (explant) was developed for the evaluation of the initial osseointegration behavior of implant materials. The model was tested with additive manufactured Ti6Al4V test substrates …
View article: Development of Bioinspired Functional Chitosan/Cellulose Nanofiber 3D Hydrogel Constructs by 3D Printing for Application in the Engineering of Mechanically Demanding Tissues
Development of Bioinspired Functional Chitosan/Cellulose Nanofiber 3D Hydrogel Constructs by 3D Printing for Application in the Engineering of Mechanically Demanding Tissues Open
Soft tissues are commonly fiber-reinforced hydrogel composite structures, distinguishable from hard tissues by their low mineral and high water content. In this work, we proposed the development of 3D printed hydrogel constructs of the bio…
View article: Inverse 3D Printing with Variations of the Strand Width of the Resulting Scaffolds for Bone Replacement
Inverse 3D Printing with Variations of the Strand Width of the Resulting Scaffolds for Bone Replacement Open
The objective of this study was to vary the wall thicknesses and pore sizes of inversely printed 3D molded bodies. Wall thicknesses were varied from 1500 to 2000 to 2500 µm. The pores had sizes of 500, 750 and 1000 µm. The sacrificial stru…
View article: Mechanical Properties of the Composite Material consisting of β-TCP and Alginate-Di-Aldehyde-Gelatin Hydrogel and Its Degradation Behavior
Mechanical Properties of the Composite Material consisting of β-TCP and Alginate-Di-Aldehyde-Gelatin Hydrogel and Its Degradation Behavior Open
This work aimed to determine the influence of two hydrogels (alginate, alginate-di-aldehyde (ADA)/gelatin) on the mechanical strength of microporous ceramics, which have been loaded with these hydrogels. For this purpose, the compressive s…
View article: Analysis of Proteoglycan Content and Biomechanical Properties in Arthritic and Arthritis-Free Menisci
Analysis of Proteoglycan Content and Biomechanical Properties in Arthritic and Arthritis-Free Menisci Open
Studies on osteoarthritis of the knee have examined isolated aspects of the meniscus biomechanically and histologically, but not the difference between instantaneous modulus (IM) in healthy and diseased samples. The aim of this study is to…
View article: Histomorphological Alterations of Human Anterior Cruciate Ligament Grafts During Mid‐Term and Long‐Term Remodeling
Histomorphological Alterations of Human Anterior Cruciate Ligament Grafts During Mid‐Term and Long‐Term Remodeling Open
Objective The aim of the present paper is to analyze mid‐term and long‐term alterations of human anterior cruciate ligament (ACL) grafts during the remodeling process with special regards to cellularity, α‐smooth muscle protein (αSMP) expr…
View article: Correlation of Biomechanical Alterations under Gonarthritis between Overlying Menisci and Articular Cartilage
Correlation of Biomechanical Alterations under Gonarthritis between Overlying Menisci and Articular Cartilage Open
Just like menisci, articular cartilage is exposed to constant and varying stresses. Injuries to the meniscus are associated with the development of gonarthritis. Both the articular cartilage and the menisci are subject to structural change…
View article: Acute Joint Blockage due to Abrasion-Related Dislocation of a Silastic Radial Head Prosthesis: A Histological Examination after 14 Years of Durability
Acute Joint Blockage due to Abrasion-Related Dislocation of a Silastic Radial Head Prosthesis: A Histological Examination after 14 Years of Durability Open
The implantation of a radial head prosthesis can take place as a therapeutic option after radial head fracture. There are various implants for this purpose. Many studies and case reports about silastic radial head prosthesis implantation d…
View article: Anteversion Angle Measurement in Suspected Torsional Malalignment of the Femur in 3-Dimensional EOS vs Computed Tomography—A Validation Study
Anteversion Angle Measurement in Suspected Torsional Malalignment of the Femur in 3-Dimensional EOS vs Computed Tomography—A Validation Study Open
In torsional malalignment, EOS does not have correlation with CT measurements. In contrast to CT scan, EOS allows femoral torsion measurement independent of legs' positioning.
View article: Forsterite/nano-biogenic hydroxyapatite composites for biomedical applications
Forsterite/nano-biogenic hydroxyapatite composites for biomedical applications Open
Recently, silicate materials have received attention as materials with promising applications in the bioceramics field. A recent study aimed to investigate the effect of forsterite (Mg2SiO4) addition to biogenic hydroxyapatite, Ca10(PO4)6(…
View article: Biomechanical dynamic comparison of biodegradable pins and titanium screws for operative stabilization of displaced radial head fractures
Biomechanical dynamic comparison of biodegradable pins and titanium screws for operative stabilization of displaced radial head fractures Open
For radial head osteosynthesis, biodegradable implants are gaining in importance to minimize cartilage destruction and implant impingement and to supersede implant removal. Since loss of reduction and pseudarthrosis remain challenging comp…
View article: Thin Degradable Coatings for Optimization of Osteointegration Associated with Simultaneous Infection Prophylaxis
Thin Degradable Coatings for Optimization of Osteointegration Associated with Simultaneous Infection Prophylaxis Open
One of the most common causes of implant failure is aseptic prosthesis loosening. Another frequent complication after prosthesis implant is the microbial colonization of the prosthesis surface, which often leads to a replacement of the pro…
View article: Inversely 3D-Printed β-TCP Scaffolds for Bone Replacement
Inversely 3D-Printed β-TCP Scaffolds for Bone Replacement Open
The aim of this study was to predefine the pore structure of β-tricalcium phosphate (β-TCP) scaffolds with different macro pore sizes (500, 750, and 1000 µm), to characterize β-TCP scaffolds, and to investigate the growth behavior of cells…
View article: Alendronate Release from UHMWPE-Based Biomaterials in Relation to Particle Size of the GUR Powder for Manufacturing
Alendronate Release from UHMWPE-Based Biomaterials in Relation to Particle Size of the GUR Powder for Manufacturing Open
Ultra-high molecular weight polyethylene (UHMWPE) is widely used in endoprosthetics and has been the subject of countless studies. This project investigates the dependence of alendronate (AL) release on the molecular weight of the UHMWPE u…
View article: Carbon-Fibre-Reinforced SiC Composite (C/SiSiC) as an Alternative Material for Endoprosthesis: Fabrication, Mechanical and In-Vitro Biological Properties
Carbon-Fibre-Reinforced SiC Composite (C/SiSiC) as an Alternative Material for Endoprosthesis: Fabrication, Mechanical and In-Vitro Biological Properties Open
Particle-induced periprosthetic osteolysis and subsequent aseptic implant loosening are a major cause of compromising the long-term results of total joint replacements. To date, no implant has been able to mirror radically the tribological…
View article: Comparison of Regenerative Tissue Quality following Matrix-Associated Cell Implantation Using Amplified Chondrocytes Compared to Synovium-Derived Stem Cells in a Rabbit Model for Cartilage Lesions
Comparison of Regenerative Tissue Quality following Matrix-Associated Cell Implantation Using Amplified Chondrocytes Compared to Synovium-Derived Stem Cells in a Rabbit Model for Cartilage Lesions Open
Known problems of the autologous chondrocyte implantation motivate the search for cellular alternatives. The aim of the study was to test the potential of synovium-derived stem cells (SMSC) to regenerate cartilage using a matrix-associated…
View article: 3D Powder Printed Bioglass and β-Tricalcium Phosphate Bone Scaffolds
3D Powder Printed Bioglass and β-Tricalcium Phosphate Bone Scaffolds Open
The use of both bioglass (BG) and β tricalcium phosphate (β-TCP) for bone replacement applications has been studied extensively due to the materials’ high biocompatibility and ability to resorb when implanted in the body. 3D printing has b…
View article: High velocity suspension flame spraying (HVSFS) of metal doped bioceramic coatings
High velocity suspension flame spraying (HVSFS) of metal doped bioceramic coatings Open
•Bioceramic coatings doped with metals for antibacterial effect.•Combination of suspension and precursor flame spraying.•Successful deposition of submicron metallic particles in bioceramic matrix.
View article: Characterization and distribution of mechanically competent mineralized tissue in micropores of β-tricalcium phosphate bone substitutes
Characterization and distribution of mechanically competent mineralized tissue in micropores of β-tricalcium phosphate bone substitutes Open
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