Anke C. Fender
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View article: Factor XIII and cardiovascular disease: biomarker, culprit or victim in acute myocardial infarction outcomes?
Factor XIII and cardiovascular disease: biomarker, culprit or victim in acute myocardial infarction outcomes? Open
View article: Sex differences in the response to treatment of attention deficit hyperactivity disorder
Sex differences in the response to treatment of attention deficit hyperactivity disorder Open
Attention deficit hyperactivity disorder (ADHD) impacts markedly on juvenile development and daily function of young and adult patients. Global prevalence and drug prescription rates are consistently on the rise, particularly in young wome…
View article: Correction: Thrombin receptor PAR4 cross-activates the tyrosine kinase c-met in atrial cardiomyocytes
Correction: Thrombin receptor PAR4 cross-activates the tyrosine kinase c-met in atrial cardiomyocytes Open
View article: Recent highlights from the International Journal of Cardiology Heart & Vasculature: cardiometabolic disease
Recent highlights from the International Journal of Cardiology Heart & Vasculature: cardiometabolic disease Open
View article: Recent highlights from the International Journal of Cardiology Heart and Vasculature: cardio-oncology
Recent highlights from the International Journal of Cardiology Heart and Vasculature: cardio-oncology Open
View article: Thrombin engages neutrophil-derived secretion products to upregulate interleukin-6 production in atrial cardiomyocytes and the heart
Thrombin engages neutrophil-derived secretion products to upregulate interleukin-6 production in atrial cardiomyocytes and the heart Open
Interleukin-6 (IL-6) exerts a highly context-dependent influence on cardiac injury and repair, inflammation and resolution. Thrombin is a dichotomous regulator of these processes in the post-infarcted heart via protease-activated receptors…
View article: Diabetes and atrial fibrillation: Causality is still a black-box
Diabetes and atrial fibrillation: Causality is still a black-box Open
View article: Biomedical research as collateral damage in a new world Order?
Biomedical research as collateral damage in a new world Order? Open
View article: The inflammatory and nutritional status in patients with dilated cardiomyopathy: Different impact for distinct phenogroups?
The inflammatory and nutritional status in patients with dilated cardiomyopathy: Different impact for distinct phenogroups? Open
View article: Correction: Thrombin receptor PAR4 cross-activates the tyrosine kinase c-met in atrial cardiomyocytes
Correction: Thrombin receptor PAR4 cross-activates the tyrosine kinase c-met in atrial cardiomyocytes Open
View article: Functional characterization of OR51B5 and OR1G1 in human lung epithelial cells as potential drug targets for non-type 2 lung diseases
Functional characterization of OR51B5 and OR1G1 in human lung epithelial cells as potential drug targets for non-type 2 lung diseases Open
View article: Towards improved detection of subclinical atrial fibrillation – Who could benefit from targeted screening?
Towards improved detection of subclinical atrial fibrillation – Who could benefit from targeted screening? Open
View article: Inflammatory gut-heart interactions: Is there a link between inflammatory bowel disease and atrial fibrillation?
Inflammatory gut-heart interactions: Is there a link between inflammatory bowel disease and atrial fibrillation? Open
View article: Thrombin receptor PAR4 cross-activates the tyrosine kinase c-met in atrial cardiomyocytes
Thrombin receptor PAR4 cross-activates the tyrosine kinase c-met in atrial cardiomyocytes Open
Thrombin supports coagulation-independent inflammation via protease-activated receptors (PAR). PAR4 is specifically increased in obese human atria, correlating with NLRP3 inflammasome activation. PAR4-mediated NLRP3 inflammasome activation…
View article: Recent highlights from the International Journal of Cardiology Heart and Vasculature: Spatiotemporal and functional immunoprofiling and its theranostic potential
Recent highlights from the International Journal of Cardiology Heart and Vasculature: Spatiotemporal and functional immunoprofiling and its theranostic potential Open
View article: Recent highlights from the International Journal of Cardiology Heart & Vasculature: Basic and translational research
Recent highlights from the International Journal of Cardiology Heart & Vasculature: Basic and translational research Open
View article: Direct neuronal protection by the protease‐activated receptor PAR4 antagonist ML354 after experimental stroke in mice
Direct neuronal protection by the protease‐activated receptor PAR4 antagonist ML354 after experimental stroke in mice Open
Background and Purpose Thrombo‐inflammation is a key feature of stroke pathophysiology and provides multiple candidate drug targets. Thrombin exerts coagulation‐independent actions via protease‐activated receptors (PAR), of which PAR1 has …
View article: Direct neuronal protection by the protease-activated receptor PAR4 antagonist ML354 after experimental stroke in mice
Direct neuronal protection by the protease-activated receptor PAR4 antagonist ML354 after experimental stroke in mice Open
Background and Purpose Thrombo-inflammation is a key feature of stroke pathophysiology and provides multiple candidate drug targets. Thrombin exerts coagulation-independent actions via protease-activated receptors (PAR), of which PAR1 has …
View article: The thrombin receptor PAR4 supports visceral adipose tissue inflammation
The thrombin receptor PAR4 supports visceral adipose tissue inflammation Open
View article: Ischemia does not provoke the full immune training repertoire in human cardiac fibroblasts
Ischemia does not provoke the full immune training repertoire in human cardiac fibroblasts Open
Trained immunity of monocytes, endothelial, and smooth muscle cells augments the cytokine response to secondary stimuli. Immune training is characterized by stabilization of hypoxia-inducible factor (HIF)-1α, mTOR activation, and aerobic g…
View article: Protease-activated receptor 2 at the intersection of thrombo-inflammation and beyond
Protease-activated receptor 2 at the intersection of thrombo-inflammation and beyond Open
View article: A Short History of the Atrial Nlrp3 Inflammasome and its Distinct Role in Atrial Fibrillation
A Short History of the Atrial Nlrp3 Inflammasome and its Distinct Role in Atrial Fibrillation Open
View article: Recent highlights on specific aspects of oral anticoagulation in difficult clinical scenarios from the International Journal of Cardiology Heart & Vasculature
Recent highlights on specific aspects of oral anticoagulation in difficult clinical scenarios from the International Journal of Cardiology Heart & Vasculature Open
View article: Recent highlights from the International Journal of Cardiology Heart & Vasculature on challenges for adequate stroke prevention in patients with atrial fibrillation
Recent highlights from the International Journal of Cardiology Heart & Vasculature on challenges for adequate stroke prevention in patients with atrial fibrillation Open
View article: Rivaroxaban attenuates neutrophil maturation in the bone marrow niche
Rivaroxaban attenuates neutrophil maturation in the bone marrow niche Open
View article: Recent highlights on the mechanistic basis of cardiovascular remodeling from the International Journal of Cardiology Heart & Vasculature
Recent highlights on the mechanistic basis of cardiovascular remodeling from the International Journal of Cardiology Heart & Vasculature Open
View article: Impact of NKG2D Signaling on Natural Killer and T‐Cell Function in Cerebral Ischemia
Impact of NKG2D Signaling on Natural Killer and T‐Cell Function in Cerebral Ischemia Open
Background Typically defined as a thromboinflammatory disease, ischemic stroke features early and delayed inflammatory responses, which determine the extent of ischemia‐related brain damage. T and natural killer cells have been implicated …
View article: Protein Disulfide Isomerase and Extracellular Adherence Protein Cooperatively Potentiate Staphylococcal Invasion into Endothelial Cells
Protein Disulfide Isomerase and Extracellular Adherence Protein Cooperatively Potentiate Staphylococcal Invasion into Endothelial Cells Open
Staphylococcus aureus can invade and persist in non-professional phagocytes, thereby escaping host defense mechanisms and antibiotic treatment. The intracellular lifestyle of S. aureus contributes to the development of infection, e.g., in …
View article: Evolving insights into the pleiotropic cardioprotective mechanisms of SGLT2 inhibitors
Evolving insights into the pleiotropic cardioprotective mechanisms of SGLT2 inhibitors Open
View article: Protein disulfide isomerase and extracellular adherence protein (Eap) cooperatively potentiate staphylococcal invasion into endothelial cells
Protein disulfide isomerase and extracellular adherence protein (Eap) cooperatively potentiate staphylococcal invasion into endothelial cells Open
This data file contains images from Western blots and raw data used for the manuscript "Protein disulfide isomerase and extracellular adherence protein (Eap) cooperatively potentiate staphylococcal invasion into endothelial cells"