Anke Lange
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View article: Identification of the estrogen receptor subtypes associated with testis-ova induction in the medaka
Identification of the estrogen receptor subtypes associated with testis-ova induction in the medaka Open
Exposure to estrogenic endocrine disrupting chemicals (EDCs) poses a significant threat to aquatic wildlife. They are known to induce a range of adverse reproductive and developmental disorders that include induction of oocytes in the test…
View article: Metabolic clearance of physicochemically diverse pharmaceuticals in cultured fish hepatocytes
Metabolic clearance of physicochemically diverse pharmaceuticals in cultured fish hepatocytes Open
Fish are inherently susceptible to the exposure and effects of pharmaceutical pollutants in aquatic ecosystems and are often used to quantify the bioaccumulation and effects of active pharmaceutical ingredients (APIs) during environmental …
View article: Advancing technical understanding of the double-seeded gill cell culture system for drug uptake studies in fish
Advancing technical understanding of the double-seeded gill cell culture system for drug uptake studies in fish Open
Environmental risk assessment (ERA) is required for new drug approvals in Europe and the United States, driving the demand for reliable bioassays to model active pharmaceutical ingredient (API) uptake in fish. The rainbow trout (Oncorhynch…
View article: The potential for heat shock exposure during early development to alter the molecular responses to subsequent exposure to heat stress in the rainbow trout
The potential for heat shock exposure during early development to alter the molecular responses to subsequent exposure to heat stress in the rainbow trout Open
Fish are ectothermic animals with temperature playing a key role in their health, growth and survival. Greater occurrence of heat waves and temperature extremes, as a result of global climate change, has the potential to impact both wild a…
View article: Contaminants in shrimp probiotics - a potential emerging threat to food security
Contaminants in shrimp probiotics - a potential emerging threat to food security Open
This is the final version. Available from Elsevier via the DOI in this record.
View article: The genomic signature and transcriptional response of metal tolerance in brown trout inhabiting metal-polluted rivers
The genomic signature and transcriptional response of metal tolerance in brown trout inhabiting metal-polluted rivers Open
Industrial pollution is a major driver of ecosystem degradation, but it can also act as a driver of contemporary evolution. As a result of intense mining activity during the Industrial Revolution, several rivers across the southwest of Eng…
View article: The Role of Glutathione and Sulfhydryl Groups in Cadmium Uptake by Cultures of the Rainbow Trout RTG-2 Cell Line
The Role of Glutathione and Sulfhydryl Groups in Cadmium Uptake by Cultures of the Rainbow Trout RTG-2 Cell Line Open
The aim of this study is to investigate the role of cellular sulfhydryl and glutathione (GSH) status in cellular cadmium (Cd) accumulation using cultures of the rainbow trout cell line RTG-2. In a first set of experiments, the time course …
View article: Comparative analysis of gonadal transcriptomes between turtle and alligator identifies common molecular cues activated during the temperature-sensitive period for sex determination
Comparative analysis of gonadal transcriptomes between turtle and alligator identifies common molecular cues activated during the temperature-sensitive period for sex determination Open
The mode of sex determination in vertebrates can be categorized as genotypic or environmental. In the case of genotypic sex determination (GSD), the sexual fate of an organism is determined by the chromosome composition with some having do…
View article: Comparative Analysis of Gonadal Transcriptomes between Turtle and Alligator Identifies Common Molecular Cues Activated During the Temperature-Sensitive Period for Sex Determination
Comparative Analysis of Gonadal Transcriptomes between Turtle and Alligator Identifies Common Molecular Cues Activated During the Temperature-Sensitive Period for Sex Determination Open
View article: Resistance to white spot syndrome virus in the European shore crab is associated with suppressed virion trafficking and heightened immune responses
Resistance to white spot syndrome virus in the European shore crab is associated with suppressed virion trafficking and heightened immune responses Open
Introduction All decapod crustaceans are considered potentially susceptible to White Spot Syndrome Virus (WSSV) infection, but the degree of White Spot Disease (WSD) susceptibility varies widely between species. The European shore crab Car…
View article: Draft genome sequences of the European shore crab (Carcinus maenas)
Draft genome sequences of the European shore crab (Carcinus maenas) Open
Draft genome sequences (scaffolds) of the European shore crab (Carcinus maenas) that were generated by Verbruggen et al. (2016). Verbruggen, B. (2016). Generating genomic resources for two crustacean species and their ap…
View article: Health Effects and Life Stage Sensitivities in Zebrafish Exposed to an Estrogenic Wastewater Treatment Works Effluent
Health Effects and Life Stage Sensitivities in Zebrafish Exposed to an Estrogenic Wastewater Treatment Works Effluent Open
A wide range of health effects in fish have been reported for exposure to wastewater treatment work (WwTW) effluents including feminized responses in males. Most of these exposure studies, however, have assessed acute health effects and ch…
View article: Effects of maternal exposure to environmentally relevant concentrations of 17α-ethinyloestradiol in a live bearing freshwater fish, Xenotoca eiseni (Cyprinodontiformes, Goodeidae)
Effects of maternal exposure to environmentally relevant concentrations of 17α-ethinyloestradiol in a live bearing freshwater fish, Xenotoca eiseni (Cyprinodontiformes, Goodeidae) Open
View article: Using molecular and crowd‐sourcing methods to assess breeding ground diet of a migratory brood parasite of conservation concern
Using molecular and crowd‐sourcing methods to assess breeding ground diet of a migratory brood parasite of conservation concern Open
Breeding ground food availability is critical to the survival and productivity of adult birds. The common cuckoo Cuculus canorus is a brood‐parasitic Afro‐Palearctic migrant bird exhibiting long‐term (breeding) population declines in many …
View article: Expression dynamics of genes in the hypothalamic-pituitary-thyroid (HPT) cascade and their responses to 3,3′,5-triiodo-l-thyronine (T3) highlights potential vulnerability to thyroid-disrupting chemicals in zebrafish (Danio rerio) embryo-larvae
Expression dynamics of genes in the hypothalamic-pituitary-thyroid (HPT) cascade and their responses to 3,3′,5-triiodo-l-thyronine (T3) highlights potential vulnerability to thyroid-disrupting chemicals in zebrafish (Danio rerio) embryo-larvae Open
View article: Supplementary Material for: Ontogeny and Dynamics of the Gonadal Development, Embryogenesis, and Gestation in Xenotoca eiseni (Cyprinodontiformes, Goodeidae)
Supplementary Material for: Ontogeny and Dynamics of the Gonadal Development, Embryogenesis, and Gestation in Xenotoca eiseni (Cyprinodontiformes, Goodeidae) Open
We characterized the ontogeny and dynamics of gonadal development, embryogenesis, and gestation in captive stocks of the viviparous redtail splitfin, Xenotoca eiseni. Using histology, we showed that gonads were fully differentiated …
View article: Molecular mechanisms and tissue targets of brominated flame retardants, BDE-47 and TBBPA, in embryo-larval life stages of zebrafish (Danio rerio)
Molecular mechanisms and tissue targets of brominated flame retardants, BDE-47 and TBBPA, in embryo-larval life stages of zebrafish (Danio rerio) Open
View article: Functional distinctions associated with the diversity of sex steroid hormone receptors ESR and AR
Functional distinctions associated with the diversity of sex steroid hormone receptors ESR and AR Open
View article: Early life exposure to ethinylestradiol enhances subsequent responses to environmental estrogens measured in a novel transgenic zebrafish
Early life exposure to ethinylestradiol enhances subsequent responses to environmental estrogens measured in a novel transgenic zebrafish Open
View article: Establishment of estrogen receptor 1 (ESR1)‐knockout medaka: <scp>ESR</scp>1 is dispensable for sexual development and reproduction in medaka, <i>Oryzias latipes</i>
Establishment of estrogen receptor 1 (ESR1)‐knockout medaka: <span>ESR</span>1 is dispensable for sexual development and reproduction in medaka, <i>Oryzias latipes</i> Open
Estrogens play fundamental roles in regulating reproductive activities and they act through estrogen receptor ( ESR ) in all vertebrates. Most vertebrates have two ESR subtypes ( ESR 1 and ESR 2), whereas teleost fish have at least three (…
View article: Environmental chemicals active as human antiandrogens do not activate a stickleback androgen receptor but enhance a feminising effect of oestrogen in roach
Environmental chemicals active as human antiandrogens do not activate a stickleback androgen receptor but enhance a feminising effect of oestrogen in roach Open