Ann E. Sprague
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View article: <scp>COVID</scp>‐19 vaccination around the time of conception and risk of placenta‐mediated adverse pregnancy outcomes
<span>COVID</span>‐19 vaccination around the time of conception and risk of placenta‐mediated adverse pregnancy outcomes Open
Introduction Although numerous studies have documented no association between COVID‐19 vaccination during pregnancy and maternal and fetal health outcomes, fewer studies have evaluated fetal health effects after COVID‐19 vaccination around…
View article: Mortality Following Childbirth in Ontario: A 20-Year Analysis of Temporal Trends and Causes
Mortality Following Childbirth in Ontario: A 20-Year Analysis of Temporal Trends and Causes Open
Most deaths within 1 year of childbirth are not related to obstetrical factors; however, pregnancy complications factor in early deaths. Causes of early and late deaths differ, but examining late deaths is equally important to identify fac…
View article: Changes associated with the <scp>COVID</scp>‐19 pandemic on postpartum screening results in Ontario, Canada: The healthy babies healthy children screening tool
Changes associated with the <span>COVID</span>‐19 pandemic on postpartum screening results in Ontario, Canada: The healthy babies healthy children screening tool Open
Background Research on the impact of the COVID‐19 pandemic on mothers/childbearing parents has mainly been cross‐sectional and focused on psychological symptoms. This study examined the impact on function using ongoing, systematic screenin…
View article: Maternal Deaths Using Coroner’s Data: A Latent Class Analysis
Maternal Deaths Using Coroner’s Data: A Latent Class Analysis Open
Peri-pregnancy maternal deaths can be classified into three distinct sub-types, with somewhat differing causes. These findings may enhance clinical and policy development aimed at reducing pregnancy mortality.
View article: Pregnancy, fetal, and neonatal outcomes after a first booster dose of covid-19 vaccine during pregnancy in Ontario, Canada: population based, retrospective cohort study
Pregnancy, fetal, and neonatal outcomes after a first booster dose of covid-19 vaccine during pregnancy in Ontario, Canada: population based, retrospective cohort study Open
Objective To assess risk of adverse pregnancy, fetal, and neonatal outcomes after a third dose (first booster dose) of covid-19 vaccine during pregnancy among individuals who had completed both doses of primary covid-19 vaccine series befo…
View article: Temporal trends and determinants of COVID-19 vaccine series initiation after recent pregnancy
Temporal trends and determinants of COVID-19 vaccine series initiation after recent pregnancy Open
During the rapid deployment of COVID-19 vaccines in 2021, safety concerns may have led some pregnant individuals to postpone vaccination until after giving birth. This study aimed to describe temporal patterns and factors associated with C…
View article: Temporal trends and determinants of COVID-19 vaccine coverage and series initiation during pregnancy in Ontario, Canada, December 2020 to December 2021: A population-based retrospective cohort study
Temporal trends and determinants of COVID-19 vaccine coverage and series initiation during pregnancy in Ontario, Canada, December 2020 to December 2021: A population-based retrospective cohort study Open
COVID-19 vaccine coverage among pregnant individuals remained lower than in the general population, and there was lower vaccine initiation by multiple characteristics.
View article: The Canadian Mother-Child Cohort Active Surveillance Initiative (CAMCCO): Comparisons between Quebec, Manitoba, Saskatchewan, and Alberta
The Canadian Mother-Child Cohort Active Surveillance Initiative (CAMCCO): Comparisons between Quebec, Manitoba, Saskatchewan, and Alberta Open
Background Given that pregnant women taking medications are excluded from clinical trials, real-world evidence is essential. We aimed to build a Canadian Mother-Child Cohort Active Surveillance Initiative (CAMCCO) and compare frequency of …
View article: Risk of preterm birth, small for gestational age at birth, and stillbirth after covid-19 vaccination during pregnancy: population based retrospective cohort study
Risk of preterm birth, small for gestational age at birth, and stillbirth after covid-19 vaccination during pregnancy: population based retrospective cohort study Open
Objective To assess the risk of preterm birth, small for gestational age at birth, and stillbirth after covid-19 vaccination during pregnancy. Design Population based retrospective cohort study. Setting Ontario, Canada, 1 May to 31 Decembe…
View article: Association of SARS-CoV-2 Infection During Pregnancy With Maternal and Perinatal Outcomes
Association of SARS-CoV-2 Infection During Pregnancy With Maternal and Perinatal Outcomes Open
In this exploratory surveillance study conducted in Canada from March 2020 to October 2021, SARS-CoV-2 infection during pregnancy was significantly associated with increased risk of adverse maternal outcomes and preterm birth.
View article: Association of COVID-19 Vaccination in Pregnancy With Adverse Peripartum Outcomes
Association of COVID-19 Vaccination in Pregnancy With Adverse Peripartum Outcomes Open
In this population-based cohort study in Ontario, Canada, COVID-19 vaccination during pregnancy, compared with vaccination after pregnancy and with no vaccination, was not significantly associated with increased risk of adverse peripartum …
View article: Association of Maternal Influenza Vaccination During Pregnancy With Early Childhood Health Outcomes
Association of Maternal Influenza Vaccination During Pregnancy With Early Childhood Health Outcomes Open
In this population-based cohort study with mean follow-up duration of 3.6 years, maternal influenza vaccination during pregnancy was not significantly associated with an increased risk of adverse early childhood health outcomes.
View article: Client Experience with the Ontario Birth Center Demonstration Project
Client Experience with the Ontario Birth Center Demonstration Project Open
Introduction In 2014, 2 new freestanding midwifery‐led birth centers opened in Ontario, Canada. As one part of a larger mixed‐methods evaluation of the first year of operations of the centers, our primary objective was to compare the exper…
View article: Associations of Assisted Reproductive Technology and Twin Pregnancy With Risk of Congenital Heart Defects
Associations of Assisted Reproductive Technology and Twin Pregnancy With Risk of Congenital Heart Defects Open
Our study results suggest that the association between assisted reproductive technology and congenital heart defects may be mediated by twinning.
View article: The Canadian Assisted Reproductive Technologies Register (CARTR) Plus database: a validation study
The Canadian Assisted Reproductive Technologies Register (CARTR) Plus database: a validation study Open
STUDY QUESTION Are data accurately documented in the Canadian Assisted Reproductive Technologies Register (CARTR) Plus database? SUMMARY ANSWER Measures of validity were strong for the majority of variables evaluated while those with moder…
View article: Health outcomes of young children born to mothers who received 2009 pandemic H1N1 influenza vaccination during pregnancy: retrospective cohort study
Health outcomes of young children born to mothers who received 2009 pandemic H1N1 influenza vaccination during pregnancy: retrospective cohort study Open
Objective To determine whether any association exists between exposure to 2009 pandemic H1N1 (pH1N1) influenza vaccination during pregnancy and negative health outcomes in early childhood. Design Retrospective cohort study. Setting Populat…
View article: Use of a maternal newborn audit and feedback system in Ontario: a collective case study
Use of a maternal newborn audit and feedback system in Ontario: a collective case study Open
Background As part of a larger study examining the effectiveness of the Maternal Newborn Dashboard, an electronic audit and feedback system to improve maternal-newborn care practices and outcomes, the purpose of this study was to increase …
View article: A population-based comparison of preterm neonatal deaths (22–34 gestational weeks) in France and Ontario: a cohort study
A population-based comparison of preterm neonatal deaths (22–34 gestational weeks) in France and Ontario: a cohort study Open
Even after we adjusted for both intrinsic population differences and differences in management between Ontario and France, we found a higher rate of neonatal mortality at earlier gestational ages in France. This may be related to differenc…
View article: Outcomes for the First Year of Ontario's Birth Center Demonstration Project
Outcomes for the First Year of Ontario's Birth Center Demonstration Project Open
Introduction In 2014, Ontario opened 2 stand‐alone midwifery‐led birth centers. Using mixed methods, we evaluated the first year of operations for quality and safety, client experience, and integration into the maternity care community. Th…
View article: The Integration of Ontario Birth Centers into Existing Maternal‐Newborn Services: Health Care Provider Experiences
The Integration of Ontario Birth Centers into Existing Maternal‐Newborn Services: Health Care Provider Experiences Open
Introduction In 2014, 2 freestanding, midwifery‐led birth centers opened in Ontario, Canada. The purpose of this study was to qualitatively investigate the integration of the birth centers into the local, preexisting intrapartum systems fr…