Nhu‐An Pham
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View article: Table S1 from Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non–Small Cell Lung Cancer
Table S1 from Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non–Small Cell Lung Cancer Open
Statistical association of clinical and pathologic characteristics with engraftment
View article: Supplementary Figure 1 from Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non–Small Cell Lung Cancer
Supplementary Figure 1 from Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non–Small Cell Lung Cancer Open
S1. The associations of ACO2 expression with NSCLC patient outcomes, and with cell line proliferation in vitro and in vivo.
View article: Supplementary Data 1 from Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non–Small Cell Lung Cancer
Supplementary Data 1 from Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non–Small Cell Lung Cancer Open
Clinical information and proteome quantification
View article: Supplementary Figure 2 from Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non–Small Cell Lung Cancer
Supplementary Figure 2 from Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non–Small Cell Lung Cancer Open
S2. The associations of ACO2 expression and iron on cell proliferation and expression of proteins involved in iron regulation and ferroptosis.
View article: The Emotion and Symptom‐Focused Engagement (EASE) Psychotherapeutic Intervention for Parents of Children With Acute Leukemia: A Feasibility Trial
The Emotion and Symptom‐Focused Engagement (EASE) Psychotherapeutic Intervention for Parents of Children With Acute Leukemia: A Feasibility Trial Open
Background Parents of children newly diagnosed with acute leukemia (AL) experience significant traumatic stress that adversely affects their well‐being, caregiving capacity, and family functioning. However, rigorous evidence of the feasibi…
View article: Modeling response to the KRAS-G12C inhibitor AZD4625 in KRASG12C NSCLC patient-derived xenografts reveals insights into primary resistance mechanisms
Modeling response to the KRAS-G12C inhibitor AZD4625 in KRASG12C NSCLC patient-derived xenografts reveals insights into primary resistance mechanisms Open
Our findings confirm AZD4625 as a highly active KRASG12C inhibitor. This data also supports the use of PDX models in understanding resistance mechanisms that may be leveraged to develop more active combination therapies.
View article: Lymphocytic Interstitial Pneumonia Presenting as an Enlarging Pulmonary Nodule in a 65-Year-Old Woman: A Case Report
Lymphocytic Interstitial Pneumonia Presenting as an Enlarging Pulmonary Nodule in a 65-Year-Old Woman: A Case Report Open
View article: Automated Foveal Avascular Zone Segmentation in Optical Coherence Tomography Angiography Across Multiple Eye Diseases Using Knowledge Distillation
Automated Foveal Avascular Zone Segmentation in Optical Coherence Tomography Angiography Across Multiple Eye Diseases Using Knowledge Distillation Open
Optical coherence tomography angiography (OCTA) is a noninvasive imaging technique used to visualize retinal blood flow and identify changes in vascular density and enlargement or distortion of the foveal avascular zone (FAZ), which are in…
View article: Corrigendum to ‘Humanized Mouse Models for Immuno-Oncology Research: A Review and Implications in Lung Cancer Research’ [JTO Clinical and Research Reports Volume 6 Issue 3 (2025) 100781]
Corrigendum to ‘Humanized Mouse Models for Immuno-Oncology Research: A Review and Implications in Lung Cancer Research’ [JTO Clinical and Research Reports Volume 6 Issue 3 (2025) 100781] Open
[This corrects the article DOI: 10.1016/j.jtocrr.2024.100781.].
View article: Differential Gene Expression Analysis of The Cancer Genome Atlas Messenger Ribonucleic Acid Sequencing Data from Male Patients with and without Lymph Node Metastasis in Tongue Cancer
Differential Gene Expression Analysis of The Cancer Genome Atlas Messenger Ribonucleic Acid Sequencing Data from Male Patients with and without Lymph Node Metastasis in Tongue Cancer Open
Gene expression plays a crucial role in progression, invasion, and metastasis in many groups of oral squamous cell carcinoma. Based on extensive patient data, no research has been done so far on the differences in gene expression between g…
View article: Humanized Mouse Models for Immuno-Oncology Research: A Review and Implications in Lung Cancer Research
Humanized Mouse Models for Immuno-Oncology Research: A Review and Implications in Lung Cancer Research Open
Cancer immunotherapy has brought significant clinical benefits to patients with cancer, including those with lung cancer. Patient-derived tumor xenograft mouse models have become the preferred animal model for translational cancer research…
View article: Pan-cancer<i>N</i>-glycoproteomic atlas of patient-derived xenografts uncovers FAT2 as a therapeutic target for head and neck cancers
Pan-cancer<i>N</i>-glycoproteomic atlas of patient-derived xenografts uncovers FAT2 as a therapeutic target for head and neck cancers Open
SUMMARY Cell surface proteins offer significant cancer therapeutic potential attributable to their accessible membrane localization and central role in cellular signaling. Despite this, their promise remains largely untapped due to the tec…
View article: Supplementary Figure S8 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
Supplementary Figure S8 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma Open
The oncogenic function of EML4.
View article: Supplementary Table S6 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
Supplementary Table S6 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma Open
Sample information and analysis in the internal cohort.
View article: Supplementary Table S8 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
Supplementary Table S8 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma Open
Information of EML4 and IgG control antibody precipitated proteins identified by Co-IP/MS.
View article: Supplementary Video S1 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
Supplementary Video S1 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma Open
Live cell imaging of control A549 cells in wound healing assay.
View article: Supplementary Table S9 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
Supplementary Table S9 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma Open
Sequence information of primers, siRNAs, shRNAs and sgRNAs.
View article: Supplementary Figure S6 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
Supplementary Figure S6 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma Open
Global m6A hypo-methylation in LUAD.
View article: Supplementary Methods from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
Supplementary Methods from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma Open
All methods used in this study.
View article: Supplementary Video S5 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
Supplementary Video S5 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma Open
Live cell imaging of EML4-overexpressing H358 cells in wound healing assay.
View article: Supplementary Figure S5 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
Supplementary Figure S5 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma Open
The function of BLVRA m6A.
View article: Supplementary Table S3 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
Supplementary Table S3 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma Open
m6A, mRNA and protein level-based clustering.
View article: Supplementary Table S7 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
Supplementary Table S7 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma Open
RNA-seq analysis of EML4-overexpressing, EML4-knockdown and control NSCLC cell samples.
View article: Supplementary Table S2 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
Supplementary Table S2 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma Open
Gene enrichment of G1-3 groups.
View article: Supplementary Video S4 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
Supplementary Video S4 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma Open
Live cell imaging of EML4-overexpressing H358 cells in wound healing assay.
View article: Supplementary Figure S11 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
Supplementary Figure S11 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma Open
Toxicity assessment of STM2457 treatment.
View article: Supplementary Table S1 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
Supplementary Table S1 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma Open
Sample information and gene list of NL-specific, tumor-specific and common methylated genes.
View article: Supplementary Figure S4 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
Supplementary Figure S4 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma Open
Association of m6A with clinical features and patient survival.
View article: Supplementary Figure S1 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
Supplementary Figure S1 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma Open
Characteristics of m6A peaks and methodological comparison for m6A level calculation.
View article: Supplementary Figure S10 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
Supplementary Figure S10 from The N<sup>6</sup>-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma Open
Analysis of EML4 and METTL3 protein levels in LUAD patient tumors and functional assays of METTL3 perturbation.