Karen A. Power
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View article: Equine sarcoids from Southern Italy: Molecular and Histopathological characterization
Equine sarcoids from Southern Italy: Molecular and Histopathological characterization Open
This study investigated the presence of δ bovine papillomaviruses (BPV-1, BPV-2, BPV-13, BPV-14) in equine skin lesions from Southern Italy, focusing on equine sarcoids and their histopathological correlations. 63 equine skin samples were …
View article: Immunohistochemical Detection of Iron-Related Proteins in Sertoli Cell-Only Patterns in Canine Testicular Lesions
Immunohistochemical Detection of Iron-Related Proteins in Sertoli Cell-Only Patterns in Canine Testicular Lesions Open
Sertoli cell-only (SCO) tubules are a histologic pattern characterized by the absence of germ cells within seminiferous tubules, leading to infertility in both humans and dogs. While its association with testicular tumors has been document…
View article: Ferritinophagy: a possible new iron-related metabolic target in canine osteoblastic osteosarcoma
Ferritinophagy: a possible new iron-related metabolic target in canine osteoblastic osteosarcoma Open
Canine osteosarcomas (COS) are the most common bone tumors in dogs, characterized by high metastatic rates, poor prognosis, and poor responsiveness to routine therapies, which highlights the need for new treatment targets. In this context,…
View article: Effects of pollen enriched diet on hypopharyngeal glands’ morphology and morphometry and vitellogenin transcription levels in honey bees
Effects of pollen enriched diet on hypopharyngeal glands’ morphology and morphometry and vitellogenin transcription levels in honey bees Open
Pollen proteins are necessary for the development of the hypopharyngeal glands (HPGs), and for Vitellogenin (VG) synthesis, responsible for producing royal jelly, essential for larval development and queen feeding. This study aims to evalu…
View article: Transferrin Receptor 2 in Canine Testicular Tumors: An Emerging Key Role in Seminomas
Transferrin Receptor 2 in Canine Testicular Tumors: An Emerging Key Role in Seminomas Open
Transferrin Receptor 2 (TfR2) is a homolog of Transferrin Receptor 1 (TfR1), involved in regulating intra and extracellular iron levels. Altered iron pathways have been associated with cancer onset and progression; however, their role in c…
View article: Acute GvHD of the Gut Is Associated with Minor Histocompatibility Antigens Cross-Reactive Against Gut-Tropic Viral Epitopes
Acute GvHD of the Gut Is Associated with Minor Histocompatibility Antigens Cross-Reactive Against Gut-Tropic Viral Epitopes Open
Background: The gastrointestinal system (GI) is often affected by acute Graft-versus-Host-Disease (aGvHD), and severe manifestations of aGvHD of the gut portend a poor prognosis after allogeneic hematopoietic cell transplantation (allo-HCT…
View article: Overexpression of the key metabolic protein Carnitine Palmitoyl Transferase 1A (CPT1A) in equine sarcoid
Overexpression of the key metabolic protein Carnitine Palmitoyl Transferase 1A (CPT1A) in equine sarcoid Open
The equine sarcoid is the most common skin neoplasia of fibroblastic origin in horses, characterized by an excessive accumulation of extracellular matrix produced by sarcoid fibroblasts under hypoxic condition. Neoplastic cells can adapt t…
View article: Preliminary Evidence of the Possible Roles of the Ferritinophagy-Iron Uptake Axis in Canine Testicular Cancer
Preliminary Evidence of the Possible Roles of the Ferritinophagy-Iron Uptake Axis in Canine Testicular Cancer Open
Iron is a key element in spermatogenesis; its metabolic pathway in the testis is strictly regulated. Alterations in iron metabolism are linked to various diseases, including cancer, and changes in iron metabolism-related proteins have been…
View article: Mass mortality of Cornu aspersum in Italian snail farms: A histopathological survey
Mass mortality of Cornu aspersum in Italian snail farms: A histopathological survey Open
The production demand of edible snails in the Mediterranean area is very high and the attention to snail borne diseases is increasing. Following mass mortality events, we have analyzed 240 samples of Cornu aspersum collected from farms acr…
View article: Droplet Digital RT-PCR (dd RT-PCR) Detection of SARS-CoV-2 in Honey Bees and Honey Collected in Apiaries across the Campania Region
Droplet Digital RT-PCR (dd RT-PCR) Detection of SARS-CoV-2 in Honey Bees and Honey Collected in Apiaries across the Campania Region Open
Coronaviruses (CoVs), a subfamily of Orthocoronavirinae, are viruses that sometimes present a zoonotic character. Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is responsible for the recent outbreak of COVID-19, which, since…
View article: A VRC13-like bNAb response is associated with complex escape pathways in HIV-1 envelope
A VRC13-like bNAb response is associated with complex escape pathways in HIV-1 envelope Open
The rational design of HIV-1 immunogens to trigger the development of broadly neutralizing antibodies (bNAbs) requires understanding the viral evolutionary pathways influencing this process. An acute HIV-1-infected individual exhibiting >5…
View article: Validation of dried blood spots for capturing hepatitis C virus diversity for genomic surveillance
Validation of dried blood spots for capturing hepatitis C virus diversity for genomic surveillance Open
Dried blood spots (DBS) have emerged as a promising alternative to traditional venous blood for hepatitis C virus (HCV) testing. However, their capacity to accurately reflect the genetic diversity of HCV remains poorly understood. We emplo…
View article: Sirtuin 1 Expression in Canine Mammary Tumors: A Pilot Study
Sirtuin 1 Expression in Canine Mammary Tumors: A Pilot Study Open
Sirtuin 1 (SIRT1) is a protein involved in aging, cell protection, and energy metabolism in mammals. Recently, SIRT1 has been intensively studied in medical oncology, but the role of SIRT1 is still controversial, as it has been proposed as…
View article: Validation of Dried Blood Spots for Capturing Hepatitis C Virus Diversity for Genomic Surveillance
Validation of Dried Blood Spots for Capturing Hepatitis C Virus Diversity for Genomic Surveillance Open
Dried blood spots (DBS) have emerged as a promising alternative to traditional venous blood for HCV testing. However, their capacity to accurately reflect the genetic diversity of HCV remains poorly understood. We employed deep sequencing …
View article: Detection of honey bee viruses in larvae of Vespa orientalis
Detection of honey bee viruses in larvae of Vespa orientalis Open
The Oriental hornet ( Vespa orientalis ) is one of the major predators of honey bees. It has been demonstrated that adults of V. orientalis can harbor honey bee viruses, however the transmission route of infection is still not clear. The a…
View article: Training in Honey Bee Veterinary Medicine in Italy: An Observational Study and Practical Proposals to Face Professional Challenges
Training in Honey Bee Veterinary Medicine in Italy: An Observational Study and Practical Proposals to Face Professional Challenges Open
Honey bees, like other livestock, may be affected by infectious, parasitic, and abiotic diseases that need proper sanitary monitoring and control. Currently, there are limited opportunities for undergraduate students to receive education i…
View article: Prevalence of Eucoleus garfiai in Wild Boars Hunted at Different Altitudes in the Campania and Latium Regions (Italy)
Prevalence of Eucoleus garfiai in Wild Boars Hunted at Different Altitudes in the Campania and Latium Regions (Italy) Open
Recent reports of Eucoleus garfiai in wild boars in southern Italy have highlighted the need for collecting epidemiological data on the presence of this parasite and understanding the role of possible interactions between wild boars, E. ga…
View article: Microwaves Induce Histological Alteration of Ovaries and Testis in Rhynchophorus ferrugineus Oliv. (Coleoptera: Curculionidae)
Microwaves Induce Histological Alteration of Ovaries and Testis in Rhynchophorus ferrugineus Oliv. (Coleoptera: Curculionidae) Open
The Red Palm Weevil (RPW) is one of the major pests of palms, frequently leading to the plants death. Action plans and the development of bio/physical strategies to contrast RPW diffusions are strongly recommended due to the serious concer…
View article: Detection of Honeybee Viruses in Vespa orientalis
Detection of Honeybee Viruses in Vespa orientalis Open
The Oriental hornet ( Vespa orientalis ) is spreading across the Italian territory threatening the health and wellbeing of honeybees by feeding on adult individuals and larvae and by plundering hive resources. Considering the capacity of o…
View article: Beclin 1, LC3 and P62 Expression in Equine Sarcoids
Beclin 1, LC3 and P62 Expression in Equine Sarcoids Open
Background: It is well known that δ-bovine papillomaviruses (BPV-1, BPV-2 and BPV-13) are one of the major causative agents of equine sarcoids, the most common equine skin tumors. Different viruses, including papillomaviruses, evolved inge…
View article: Histopathological Features of Symptomatic and Asymptomatic Honeybees Naturally Infected by Deformed Wing Virus
Histopathological Features of Symptomatic and Asymptomatic Honeybees Naturally Infected by Deformed Wing Virus Open
Deformed wing virus (DWV) is capable of infecting honeybees at every stage of development causing symptomatic and asymptomatic infections. To date, very little is known about the histopathological lesions caused by the virus. Therefore, 40…
View article: Innate Immune Reconstitution in Humanized Bone Marrow-Liver-Thymus (HuBLT) Mice Governs Adaptive Cellular Immune Function and Responses to HIV-1 Infection
Innate Immune Reconstitution in Humanized Bone Marrow-Liver-Thymus (HuBLT) Mice Governs Adaptive Cellular Immune Function and Responses to HIV-1 Infection Open
Humanized bone marrow-liver-thymus (HuBLT) mice are a revolutionary small-animal model that has facilitated the study of human immune function and human-restricted pathogens, including human immunodeficiency virus type 1 (HIV-1). These mic…