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View article: Genomic analysis of Candida auris transmission within an urban region
Genomic analysis of Candida auris transmission within an urban region Open
Candida auris emerged in Chicago, IL, USA, in 2016 and has since become endemic. We used whole-genome sequencing (WGS) of 494 isolates, epidemiologic metadata and patient transfer data to describe the transmission of C. auris among Chicago…
View article: Transmission patterns of<i>Candida auris</i>among regional healthcare facilities revealed by genomic epidemiology and patient transfer data
Transmission patterns of<i>Candida auris</i>among regional healthcare facilities revealed by genomic epidemiology and patient transfer data Open
Candida auris emerged in Chicago, IL, USA in 2016 and has since become endemic. We used whole genome sequencing (WGS) of 494 isolates, epidemiologic metadata, and patient transfer data to describe the transmission of C. auris among Chicago…
View article: Descriptive analysis of targeted carbapenemase genes and antibiotic susceptibility profiles among carbapenem-resistant <i>Acinetobacter baumannii</i> tested in the Antimicrobial Resistance Laboratory Network—United States, 2017–2020
Descriptive analysis of targeted carbapenemase genes and antibiotic susceptibility profiles among carbapenem-resistant <i>Acinetobacter baumannii</i> tested in the Antimicrobial Resistance Laboratory Network—United States, 2017–2020 Open
Acinetobacter baumannii is a Gram-negative bacillus that can cause severe and difficult-to-treat healthcare-associated infections. A. baumannii can harbor mobile genetic elements carrying genes that produce carbapenemase enzymes, further l…
View article: 2747. Aztreonam-Avibactam Susceptibility Testing Program for Metallo-β-Lactamase-Producing Enterobacterales collected through the Antimicrobial Resistance Laboratory Network, March 2019 to April 2023
2747. Aztreonam-Avibactam Susceptibility Testing Program for Metallo-β-Lactamase-Producing Enterobacterales collected through the Antimicrobial Resistance Laboratory Network, March 2019 to April 2023 Open
Background Metallo-β-lactamase-producing Enterobacterales (MBL-E) are a major public health concern as they cause infections with few effective treatment options. Aztreonam-avibactam (AZA) is a β-lactam/β-lactamase inhibitor combination ag…
View article: 1445. Public Health Containment Response Detects Possible Transmission of Echinocandin-Resistant <i>Candida auris</i> in a Long-term Acute Care Hospital
1445. Public Health Containment Response Detects Possible Transmission of Echinocandin-Resistant <i>Candida auris</i> in a Long-term Acute Care Hospital Open
Background Candida auris is an emerging fungal pathogen which is often multidrug-resistant, can cause severe infections, and spreads readily in healthcare settings. While echinocandin resistance (ech-R) remains low in the United States (&l…
View article: Antimicrobial Resistance Laboratory Network’s multisite evaluation of the ThermoFisher Sensititre GN7F broth microdilution panel for antimicrobial susceptibility testing
Antimicrobial Resistance Laboratory Network’s multisite evaluation of the ThermoFisher Sensititre GN7F broth microdilution panel for antimicrobial susceptibility testing Open
In 2017, the Centers for Disease Control and Prevention (CDC) established the Antimicrobial Resistance Laboratory Network to improve domestic detection of multidrug-resistant organisms. CDC and four laboratories evaluated a commercial brot…
View article: Outbreak investigation of CRAB at an acute-care hospital ICU during the COVID-19 pandemic–Chicago, Illinois, March 2020–September 2021
Outbreak investigation of CRAB at an acute-care hospital ICU during the COVID-19 pandemic–Chicago, Illinois, March 2020–September 2021 Open
Background: Carbapenem-resistant Acinetobacter baumannii (CRAB) is primarily associated with hospital-acquired infections and is an urgent public health threat due to its ability to contaminate the environment and cause severe disease. In …
View article: Carbapenemase production among less-common Enterobacterales genera: 10 US sites, 2018
Carbapenemase production among less-common Enterobacterales genera: 10 US sites, 2018 Open
Background Historically, United States’ carbapenem-resistant Enterobacterales (CRE) surveillance and mechanism testing focused on three genera: Escherichia, Klebsiella, and Enterobacter (EsKE); however, other genera can harbour mobile carb…
View article: Repeated Prevalence Surveys and Admission Screening for <i>Candida auris</i> at One Long-Term Acute-Care Hospital, Chicago, 2016–2019
Repeated Prevalence Surveys and Admission Screening for <i>Candida auris</i> at One Long-Term Acute-Care Hospital, Chicago, 2016–2019 Open
Background: Since the initial identification of Candida auris in 2016 in Chicago, ongoing spread has been documented in the Chicago area, primarily among older adults with complex medical issues admitted to high-acuity long-term care facil…
View article: <i>Candida auris</i> and Carbapenemase-Producing Organism Prevalence in an Extended Stay Pediatric Hospital, Chicago, Illinois, 2019
<i>Candida auris</i> and Carbapenemase-Producing Organism Prevalence in an Extended Stay Pediatric Hospital, Chicago, Illinois, 2019 Open
Background: Candida auris and carbapenemase-producing organisms (CPO) are multidrug-resistant organisms that can colonize people for prolonged periods and can cause invasive infections and spread in healthcare settings, particularly in hig…
View article: Regional Emergence of<i>Candida auris</i>in Chicago and Lessons Learned From Intensive Follow-up at 1 Ventilator-Capable Skilled Nursing Facility
Regional Emergence of<i>Candida auris</i>in Chicago and Lessons Learned From Intensive Follow-up at 1 Ventilator-Capable Skilled Nursing Facility Open
Background Since the identification of the first 2 Candida auris cases in Chicago, Illinois, in 2016, ongoing spread has been documented in the Chicago area. We describe C. auris emergence in high-acuity, long-term healthcare facilities an…
View article: 2852. Epidemiology of Emerging Carbapenemase-Producing Organisms (CPO) in Chicago, Illinois, 2013–2018
2852. Epidemiology of Emerging Carbapenemase-Producing Organisms (CPO) in Chicago, Illinois, 2013–2018 Open
Background Emerging CPO in the Chicago area poses clinical and infection control challenges across the spectrum of care. Since November 2013, CPO are reportable to the Illinois’ Extensively Drug-resistant Organism (XDRO) registry. We exami…