Anna Barbasz
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View article: Functional properties of Candida albicans extracellular vesicles released in the presence of the antifungal drugs amphotericin B, fluconazole and caspofungin
Functional properties of Candida albicans extracellular vesicles released in the presence of the antifungal drugs amphotericin B, fluconazole and caspofungin Open
The prevalence of diseases caused by pathogenic fungi of the Candida genus is currently a significant problem, particularly due to the emerging antifungal drug resistance and increasing number of immunocompromised individuals susceptible t…
View article: The cell membranes undergo biochemical and biophysical changes in response to hydroxycinnamic acid derivatives: ferulic acid and caffeic acid
The cell membranes undergo biochemical and biophysical changes in response to hydroxycinnamic acid derivatives: ferulic acid and caffeic acid Open
Ferulic acid (FA) and caffeic acid (CA), due to their strong antioxidant properties, are widely used both in dietary supplements and as ingredients in cosmetics. However, despite the undoubtedly beneficial properties of these molecules, th…
View article: Spectroscopic Properties and Biological Activity of Fluphenazine Conjugates with Gold Nanoparticles
Spectroscopic Properties and Biological Activity of Fluphenazine Conjugates with Gold Nanoparticles Open
Fluphenazine (FPZ) is a well-known neuroleptic that has attracted considerable scientific interest due to its biocidal, virucidal, and antitumor properties. Although methods for encapsulating and delivering FPZ to enhance its activity and …
View article: The Adsorption of Chlorpromazine on the Surface of Gold Nanoparticles and Its Effect on the Toxicity to Selected Mammalian Cells
The Adsorption of Chlorpromazine on the Surface of Gold Nanoparticles and Its Effect on the Toxicity to Selected Mammalian Cells Open
Chlorpromazine (CPZ) is a first-generation neuroleptic with well-established antitumor and antiviral properties. Currently, numerous studies are focused on developing new methods for CPZ delivery; however, the knowledge regarding its conju…
View article: Surface Charge-Modulated Toxicity of Cysteine-Stabilized Silver Nanoparticles
Surface Charge-Modulated Toxicity of Cysteine-Stabilized Silver Nanoparticles Open
The toxicity of silver nanoparticles (AgNPs) depends on their physicochemical properties. The ongoing research aims to develop effective methods for modifying AgNPs using molecules that enable control over the processes induced by nanopart…
View article: Curcumin’s membrane localization and disruptive effects on cellular processes - insights from neuroblastoma, leukemic cells, and Langmuir monolayers
Curcumin’s membrane localization and disruptive effects on cellular processes - insights from neuroblastoma, leukemic cells, and Langmuir monolayers Open
In therapies, curcumin is now commonly formulated in liposomal form, administered through injections or creams. This enhances its concentration at the cellular level compared to its natural form ingestion. Due to its hydrophobic nature, cu…
View article: Direct Interaction of Zirconia Nanoparticles with Human Immune Cells
Direct Interaction of Zirconia Nanoparticles with Human Immune Cells Open
Nanomaterials play a crucial role in various aspects of modern life. Zirconia nanoparticles, extensively employed in medicine for fortifying and stabilizing implants in reconstructive medicine, exhibit unique electrical, thermal, catalytic…
View article: Stress Conditions Affect the Immunomodulatory Potential of Candida albicans Extracellular Vesicles and Their Impact on Cytokine Release by THP-1 Human Macrophages
Stress Conditions Affect the Immunomodulatory Potential of Candida albicans Extracellular Vesicles and Their Impact on Cytokine Release by THP-1 Human Macrophages Open
Human immune cells possess the ability to react complexly and effectively after contact with microbial virulence factors, including those transported in cell-derived structures of nanometer sizes termed extracellular vesicles (EVs). EVs ar…
View article: Biochemical estimation of manganese nanoparticles reactions in native and model biological systems
Biochemical estimation of manganese nanoparticles reactions in native and model biological systems Open
Purpose Due to its physiological importance as a micronutrient, manganese supplementation requires taking into account the possibility of overdosing, which is associated with the initiation of stressogenic effects in plant cells. The use o…
View article: Advantageous/Unfavorable Effect of Quercetin on the Membranes of SK-N-SH Neuroblastoma Cells
Advantageous/Unfavorable Effect of Quercetin on the Membranes of SK-N-SH Neuroblastoma Cells Open
Quercetin is a polyphenolic compound, the effects of which raise scientists’ doubts. The results of many experiments show that it has anticancer, antiinflammatory, and antioxidant properties, while other studies indicate its pro-oxidative …
View article: Effects of 3FTx Protein Fraction from Naja ashei Venom on the Model and Native Membranes: Recognition and Implications for the Mechanisms of Toxicity
Effects of 3FTx Protein Fraction from Naja ashei Venom on the Model and Native Membranes: Recognition and Implications for the Mechanisms of Toxicity Open
Three-finger toxins are naturally occurring proteins in Elapidae snake venoms. Nowadays, they are gaining popularity because of their therapeutic potential. On the other hand, these proteins may cause undesirable reactions inside the body′…
View article: Protective Reactions of Seedlings Against Systemic and Local Zearalenone Application to Tolerant and Sensitive Wheat Varieties – Epr Studies 
Protective Reactions of Seedlings Against Systemic and Local Zearalenone Application to Tolerant and Sensitive Wheat Varieties – Epr Studies Open
BACKGROUNDAmong the environmental stressors, which oxidative action is currently widely studied, are mycotoxins. The aim of presented studies was to investigate the response of leaves of seedlings to zearalenone (ZEN) applied directly to l…
View article: Sodium hexametaphosphate–induced enhancement of silver nanoparticle toxicity towards leukemia cells
Sodium hexametaphosphate–induced enhancement of silver nanoparticle toxicity towards leukemia cells Open
Synergistic effects occurring between biologically active substances are of great importance for efficient treatment of many diseases. Therefore, the aim of research was to determine impact of sodium hexametaphosphate (HEX), which is a wel…
View article: Effect of ZnO, TiO2, Al2O3 and ZrO2 nanoparticles on wheat callus cells
Effect of ZnO, TiO2, Al2O3 and ZrO2 nanoparticles on wheat callus cells Open
Effect of metal oxide nanoparticles on calli of two wheat varieties: Parabola (stress tolerant) and Raweta (sensitive) was studied. ZnO induced 10% larger membrane damage in Raweta calli. TiO2, Al2O3, and ZrO2 caused nearly 30% greater lac…
View article: Highly efficient microwave synthesis of rhodanine and 2-thiohydantoin derivatives and determination of relationships between their chemical structures and antibacterial activity
Highly efficient microwave synthesis of rhodanine and 2-thiohydantoin derivatives and determination of relationships between their chemical structures and antibacterial activity Open
An efficient microwave-assisted synthesis of rhodanine and 2-thiohydantoin derivatives, and the correlation between their chemical structure and biological properties is reported.
View article: Exposure of human lymphoma cells (U-937) to the action of a single mycotoxin as well as in mixtures with the potential protectors 24-epibrassinolide and selenium ions
Exposure of human lymphoma cells (U-937) to the action of a single mycotoxin as well as in mixtures with the potential protectors 24-epibrassinolide and selenium ions Open
The progressive contamination of food products by mycotoxins such as zearalenone (ZEN) has prompted the search for specific substances that can act as protectors against an accumulation of these toxins. This paper discusses the effect of s…
View article: Toxicological effects of three types of silver nanoparticles and their salt precursors acting on human U-937 and HL-60 cells
Toxicological effects of three types of silver nanoparticles and their salt precursors acting on human U-937 and HL-60 cells Open
The growing popularity of nanomaterials requires a systematic study of their effects on the human body. Silver nanoparticles (AgNPs), due to their antiseptic properties, are used in almost every area of life. The purpose of the study was t…
View article: Effects of exposure of callus cells of two wheat varieties to silver nanoparticles and silver salt (AgNO3)
Effects of exposure of callus cells of two wheat varieties to silver nanoparticles and silver salt (AgNO3) Open
Metal nanoparticles significantly affect the physiological properties of plants, e.g., seed germination, growth and metabolism. In the present study, the toxic effects of silver nanoparticles (AgNPs) and silver ions were studied on callus …