Anna Sroka‐Bartnicka
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Raman spectroscopy supported by machine learning reveals changes in balance of macromolecules in diabetic rat serum Open
In type 2 diabetes mellitus (T2DM), changes in glucose and lipid levels in serum are the first signals of disease progression. In this article, Raman spectroscopy supported with machine learning (ML) was used both to determine the level of…
View article: The effect of chitosan molecular weight and its content on the mechanical, microstructural and biological parameters of biomaterial intended for cartilage tissue regeneration
The effect of chitosan molecular weight and its content on the mechanical, microstructural and biological parameters of biomaterial intended for cartilage tissue regeneration Open
Chitosan is widely used in the synthesis of modern artificial constructs, but its varying molecular weight (Mw) and deacetylation degree make selection challenging. This study examines how chitosan's Mw and concentration affect the mechani…
View article: Physicochemical Characterization of Biodegradable Polymers for Biomedical Applications: Insights from XPS, DRIFT, and AFM Techniques
Physicochemical Characterization of Biodegradable Polymers for Biomedical Applications: Insights from XPS, DRIFT, and AFM Techniques Open
Biodegradable polymers and their diverse applications, particularly in the pharmaceutical and biomedical fields, have experienced significant advancements in recent decades. The importance of this research is underscored by the potential o…
Type 2 diabetes mellitus – conventional therapies and future perspectives in innovative treatment Open
Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance and dysfunction of the pancreatic beta cells, which leads to elevated blood glucose levels. Conventional therapies, including metformin, su…
View article: Evaluation of Film-Forming Properties of α-1,3-Glucan Obtained from “Chicken of the Woods” Mushroom (Laetiporus sulphureus): Film Development, Characterization, and Biodegradation Assessment
Evaluation of Film-Forming Properties of α-1,3-Glucan Obtained from “Chicken of the Woods” Mushroom (Laetiporus sulphureus): Film Development, Characterization, and Biodegradation Assessment Open
Unlike many biopolymers, α-1,3-glucan (α-1,3-GLU) is water-insoluble, making it a promising candidate for the production of moisture-resistant films with applications in biodegradable packaging, biomedicine, and cosmetics. This study aimed…
The Absence of a Very Long Chain Fatty Acid (VLCFA) in Lipid A Impairs Agrobacterium fabrum Plant Infection and Biofilm Formation and Increases Susceptibility to Environmental Stressors Open
The Agrobacterium fabrum C58 is a phytopathogen able to infect numerous species of cultivated and ornamental plants. During infection, bacteria genetically transform plant cells and induce the formation of tumours at the site of invasion. …
Possibilities of Overcoming Resistance to Osimertinib in NSCLC Patients with Mutations in the EGFR Gene Open
The advancement of genetic research has changed the treatment management of non-small cell lung cancer (NSCLC) and opened the era of personalized medicine. Currently, three generations of EGFR tyrosine kinase inhibitors (TKIs) are used in …
Machine learning-driven Raman spectroscopy: A novel approach to lipid profiling in diabetic kidney disease Open
Diabetes mellitus is a chronic metabolic disease that increasingly affects people every year. It is known that with its progression and poor management, metabolic changes can lead to organ dysfunctions, including kidneys. The study aimed t…
The optimization of sample preparation on zebrafish larvae in vibrational spectroscopy imaging Open
The zebrafish (Danio rerio) larvae are widely used in biomedical, pharmaceutical, and ecotoxicological studies. Their transparency and translational potential make them particularly valuable for fluorescence imaging. In addition to fluores…
Lipids balance as a spectroscopy marker of diabetes. Analysis of FTIR spectra by 2D correlation and machine learning analyses Open
The number of people suffering from type 2 diabetes has rapidly increased. Taking into account, that elevated intracellular lipid concentrations, as well as their metabolism, are correlated with diminished insulin sensitivity, in this stud…
View article: Evaluation of microbially induced carbonate precipitation in repairing process of cement mortars by Raman spectroscopy
Evaluation of microbially induced carbonate precipitation in repairing process of cement mortars by Raman spectroscopy Open
The use of microorganisms that stimulate the precipitation of carbonates, which can fill the cracks that form in the structure of cementitious composites [MICP], has been gaining interest in recent years as an alternative method of self-he…
Effectiveness of the production of tissue-engineered living bone graft: a comparative study using perfusion and rotating bioreactor systems Open
Bioreactor systems are very precious tools to generate living bone grafts in vitro . The aim of this study was to compare the effectiveness of rotating and perfusion bioreactor in the production of a living bone construct. Human bone marro…
MALDI MSI and Raman Spectroscopy Application in the Analysis of the Structural Components and Flavonoids in Brassica napus Stem Open
Nod factors among the signaling molecules produced by rhizobia in response to flavonoids to induce root nodule formation in the legumes. It is, however, hypothesized that they might increase the yield and positively impact the growth of no…
EVALUATION OF THE CARIOGENICITY OF PREBIOTIC (1→3)-α-D-GLUCOOLIGOSACCHARIDES Open
One of the important features of prebiotics is their beneficial effect on the health of the host, which consists in the inhibition of the growth of harmful bacteria, including strains causing caries. The aim of the present study was to eva…
View article: Evaluation of Proteomic and Lipidomic Changes in Aeromonas-Infected Trout Kidney Tissue with the Use of FT-IR Spectroscopy and MALDI Mass Spectrometry Imaging
Evaluation of Proteomic and Lipidomic Changes in Aeromonas-Infected Trout Kidney Tissue with the Use of FT-IR Spectroscopy and MALDI Mass Spectrometry Imaging Open
Aeromonas species are opportunistic bacteria causing a vast spectrum of human diseases, including skin and soft tissue infections, meningitis, endocarditis, peritonitis, gastroenteritis, and finally hemorrhagic septicemia. The aim of our r…
Osteoclast-mediated acidic hydrolysis of thermally gelled curdlan component of the bone scaffolds: Is it possible? Open
Many biomaterials for bone regeneration have recently been produced using thermally gelled curdlan (1,3-β-d-glucan) as a binder for bioceramics. As the human organism does not produce enzymes having the ability to degrade curdlan, it is no…
View article: Surface Chemical and Morphological Analysis of Chitosan/1,3-β-d-Glucan Polysaccharide Films Cross-Linked at 90 °C
Surface Chemical and Morphological Analysis of Chitosan/1,3-β-d-Glucan Polysaccharide Films Cross-Linked at 90 °C Open
The cross-linking temperature of polymers may affect the surface characteristics and molecular arrangement, which are responsible for their mechanical and physico-chemical properties. The aim of this research was to determine and explain i…
View article: Developing Benign Ni/g-C<sub>3</sub>N<sub>4</sub> Catalysts for CO<sub>2</sub> Hydrogenation: Activity and Toxicity Study
Developing Benign Ni/g-C<sub>3</sub>N<sub>4</sub> Catalysts for CO<sub>2</sub> Hydrogenation: Activity and Toxicity Study Open
This research discusses the CO2 valorization via hydrogenation over the non-noble metal clusters of Ni and Cu supported on graphitic carbon nitride (g-C3N4). The Ni and Cu catalysts were characterized by conventional techniques including X…
Spectroscopic Evaluation of the Potential Neurotoxic Effects of a New Candidate for Anti-Seizure Medication—TP-315 during Chronic Administration (In Vivo) Open
The aim of this study was to investigate the potential neurotoxic effect of the new anti-seizure medication candidate—5-(3-chlorophenyl)-4-hexyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (TP-315), after chronic administration to mice. TP-315 …
Multimodal Spectroscopic Imaging of Pea Root Nodules to Assess the Nitrogen Fixation in the Presence of Biofertilizer Based on Nod-Factors Open
Multimodal spectroscopic imaging methods such as Matrix Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI MSI), Fourier Transform Infrared spectroscopy (FT-IR) and Raman spectroscopy were used to monitor the changes in …
View article: An Earth‐Abundant Ni‐Based Single‐Atom Catalyst for Selective Photodegradation of Pollutants
An Earth‐Abundant Ni‐Based Single‐Atom Catalyst for Selective Photodegradation of Pollutants Open
Photodegradation of Pollutants In article number 2100176, Gianvito Vilé, Manoj B. Gawande, and co-workers disclose how ligand-metal charge transfer effects in single-atom catalysts can be exploited to degrade water pollutants under visible…
View article: An Earth‐Abundant Ni‐Based Single‐Atom Catalyst for Selective Photodegradation of Pollutants
An Earth‐Abundant Ni‐Based Single‐Atom Catalyst for Selective Photodegradation of Pollutants Open
Highly efficient catalytic technologies are urgently needed to remove pharmaceutical pollutants from water. In this work, the preparation, characterization, and photocatalytic performance of an earth‐abundant Ni‐based heterogeneous catalys…
View article: Bio-DEE Synthesis and Dehydrogenation Coupling of Bio-Ethanol to Bio-Butanol over Multicomponent Mixed Metal Oxide Catalysts
Bio-DEE Synthesis and Dehydrogenation Coupling of Bio-Ethanol to Bio-Butanol over Multicomponent Mixed Metal Oxide Catalysts Open
Within the Waste2Fuel project, innovative, high-performance, and cost-effective fuel production methods from municipal solid wastes (MSWs) are sought for application as energy carriers or direct drop-in fuels/chemicals in the near-future l…
View article: Molecular Structure of Cefuroxime Axetil Complexes with α-, β-, γ-, and 2-Hydroxypropyl-β-Cyclodextrins: Molecular Simulations and Raman Spectroscopic and Imaging Studies
Molecular Structure of Cefuroxime Axetil Complexes with α-, β-, γ-, and 2-Hydroxypropyl-β-Cyclodextrins: Molecular Simulations and Raman Spectroscopic and Imaging Studies Open
The formation of cefuroxime axetil+cyclodextrin (CA+CD) complexes increases the aqueous solubility of CA, improves its physico-chemical properties, and facilitates a biomembrane-mediated drug delivery process. In CD-based tablet formulatio…
View article: CO2 Hydrogenation to Methane over Ni-Catalysts: The Effect of Support and Vanadia Promoting
CO2 Hydrogenation to Methane over Ni-Catalysts: The Effect of Support and Vanadia Promoting Open
Within the Waste2Fuel project, innovative, high-performance, and cost-effective fuel production methods are developed to target the “closed carbon cycle”. The catalysts supported on different metal oxides were characterized by XRD, XPS, Ra…