Anna Bottomley
YOU?
Author Swipe
View article: Social housing of non-rodents during cardiovascular recordings in safety pharmacology and toxicology studies
Social housing of non-rodents during cardiovascular recordings in safety pharmacology and toxicology studies Open
Although the majority of the industry does not yet socially house animals during telemetry recordings in safety pharmacology and toxicology studies, there is support to implement this refinement. Continued discussions, sharing of best prac…
View article: Evaluation of Nonacog Beta Pegol Long-term Safety in the Immune-deficient Rowett Nude Rat (Crl:NIH-<i>Foxn1<sup>rnu</sup></i>)
Evaluation of Nonacog Beta Pegol Long-term Safety in the Immune-deficient Rowett Nude Rat (Crl:NIH-<i>Foxn1<sup>rnu</sup></i>) Open
Nonacog beta pegol is a 40-kDa polyethylene glycosylated (PEGylated) human recombinant coagulation factor IX, intended for the treatment of hemophilia B. Human coagulation factors are immunogenic in animals; therefore, to evaluate the long…