Ana F. Branco
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View article: Multicriteria Optimization of Nanocellulose-Reinforced Polyvinyl Alcohol and Pyrrolidone Hydrogels
Multicriteria Optimization of Nanocellulose-Reinforced Polyvinyl Alcohol and Pyrrolidone Hydrogels Open
Developing new materials for human cartilage replacement is a hot research topic. These materials have multiple properties of interest, so selecting a new material (hydrogel) is a multi-attribute decision-making problem. A case study illus…
View article: Avaliação da adesão ao tratamento medicamentoso em pacientes diabéticos e hipertensos usuários de uma Unidade Básica de Gurupi-TO
Avaliação da adesão ao tratamento medicamentoso em pacientes diabéticos e hipertensos usuários de uma Unidade Básica de Gurupi-TO Open
A aderência ao tratamento é essencial no tratamento medicamentoso de doenças crônicas como a hipertensão arterial e o diabetes, com o objetivo de controlar e prevenir ou retardar o surgimento de complicações. No entanto, a avaliação da con…
View article: Inflammation Exacerbates Congenital Zika Virus Infection and Naringenin Provides Protective Effects
Inflammation Exacerbates Congenital Zika Virus Infection and Naringenin Provides Protective Effects Open
View article: The Low Survivability of Transplanted Gonadal Grafts: The Impact of Cryopreservation and Transplantation Conditions on Mitochondrial Function
The Low Survivability of Transplanted Gonadal Grafts: The Impact of Cryopreservation and Transplantation Conditions on Mitochondrial Function Open
Advances in tissue preservation techniques have allowed reproductive medicine and assisted reproductive technologies (ARTs) to flourish in recent years. Because radio- and chemotherapy procedures are often gonadotoxic, irreversible damage …
View article: Mitochondria as biological targets for stem cell and organismal senescence
Mitochondria as biological targets for stem cell and organismal senescence Open
Organismal aging is impacted by the deterioration of tissue turnover mechanisms due, in part, to the decline in stem cell function. This decline can be related to mitochondrial dysfunction and underlying energetic defects that, in concert,…
View article: Leucine and Arginine Availability Modulate Mouse Embryonic Stem Cell Proliferation and Metabolism
Leucine and Arginine Availability Modulate Mouse Embryonic Stem Cell Proliferation and Metabolism Open
Amino acids are crucial nutrients involved in several cellular and physiological processes, including fertilization and early embryo development. In particular, Leucine and Arginine have been shown to stimulate implantation, as lack of bot…
View article: Differential Oxygen Exposure Modulates Mesenchymal Stem Cell Metabolism and Proliferation through mTOR Signaling
Differential Oxygen Exposure Modulates Mesenchymal Stem Cell Metabolism and Proliferation through mTOR Signaling Open
Mesenchymal stem cells reside under precise hypoxic conditions that are paramount in determining cell fate and behavior (metabolism, proliferation, differentiation, etc.). In this work, we show that different oxygen tensions promote a dist…
View article: Extracellular vesicles enriched with an endothelial cell pro-survival microRNA affects skin tissue regeneration
Extracellular vesicles enriched with an endothelial cell pro-survival microRNA affects skin tissue regeneration Open
Endothelial cell (EC) activity is essential for tissue regeneration in several (patho)physiological contexts. However, our capacity to deliver in vivo biomolecules capable of controlling EC fate is relatively limited. Here, we scree…
View article: Effects of DMSO on the Pluripotency of Cultured Mouse Embryonic Stem Cells (mESCs)
Effects of DMSO on the Pluripotency of Cultured Mouse Embryonic Stem Cells (mESCs) Open
DMSO is a commonly used solvent in biological studies, as it is an amphipathic molecule soluble in both aqueous and organic media. For that reason, it is the vehicle of choice for several water-insoluble substances used in research. At the…
View article: Extreme parasitemia in P falciparum malaria
Extreme parasitemia in P falciparum malaria Open
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A 27-year-old man developed high fever after returning from sub-Saharan Africa. Trying to overcome this febrile illness during his annual leave (winter season), he had medical home visits, but the fever was repeatedly misdia…
View article: <scp>TRAP</scp>1 regulates autophagy in lung cancer cells
<span>TRAP</span>1 regulates autophagy in lung cancer cells Open
Background Expression of TRAP 1, a member of the HSP 90 chaperone family, has been implicated in tumour protective effects, based on its differential mitochondrial localization and function. Design This work was designed to provide new ins…
View article: Phytoestrogen coumestrol improves mitochondrial activity and decreases oxidative stress in the brain of ovariectomized Wistar-Han rats
Phytoestrogen coumestrol improves mitochondrial activity and decreases oxidative stress in the brain of ovariectomized Wistar-Han rats Open
View article: Ketogenic diets: from cancer to mitochondrial diseases and beyond
Ketogenic diets: from cancer to mitochondrial diseases and beyond Open
Background The employment of dietary strategies such as ketogenic diets, which force cells to alter their energy source, has shown efficacy in the treatment of several diseases. Ketogenic diets are composed of high fat, moderate protein an…
View article: Up-regulation of Proinflammatory Genes and Cytokines Induced by S100A8 in CD8+ T Cells in Lichen Planus
Up-regulation of Proinflammatory Genes and Cytokines Induced by S100A8 in CD8+ T Cells in Lichen Planus Open
Lichen planus (LP) is a chronic inflammatory mucocutaneous disease. The inflammatory status of LP may be related to S100A8 (myeloid-related protein 8; MRP8) activation of cytotoxic cells. The aims of this study were to evaluate S100A8 expr…
View article: p66Shc signaling is involved in stress responses elicited by anthracycline treatment of rat cardiomyoblasts
p66Shc signaling is involved in stress responses elicited by anthracycline treatment of rat cardiomyoblasts Open
View article: Gene Expression Profiling of H9c2 Myoblast Differentiation towards a Cardiac-Like Phenotype
Gene Expression Profiling of H9c2 Myoblast Differentiation towards a Cardiac-Like Phenotype Open
H9c2 myoblasts are a cell model used as an alternative for cardiomyocytes. H9c2 cells have the ability to differentiate towards a cardiac phenotype when the media serum is reduced in the presence of all-trans-retinoic acid (RA), creating m…