Anna E. Czapar
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View article: Association of State Legislation Restricting Reproductive and LGBT Rights With Infectious Diseases Fellowship Match Rates
Association of State Legislation Restricting Reproductive and LGBT Rights With Infectious Diseases Fellowship Match Rates Open
Background Infectious diseases (ID) fellowship match rates have declined over the last decade. Previous studies have identified factors that influence interest in ID and fellowship match rates, but the association of state legislation rest…
View article: P-960. Improving Resident Education on the Inpatient Infectious Disease Consult Service
P-960. Improving Resident Education on the Inpatient Infectious Disease Consult Service Open
Background Education in infectious disease (ID) is a critical part of an internal medicine curriculum. As the infectious disease consult service is typically high volume and busy, residents and other trainees were often not receiving adequ…
View article: P-525. HIV/STI Screening and Prevention in Hospitalized Patients with Opioid Use Disorder
P-525. HIV/STI Screening and Prevention in Hospitalized Patients with Opioid Use Disorder Open
Background Patients with opioid use disorder (OUD) are at increased risk of acquiring HIV and HCV. While this association is well-established for injection drug use (IDU), HCV and HIV transmission risk may be elevated among people with OUD…
View article: Clinical characteristics of hospitalized patients with false-negative severe acute respiratory coronavirus virus 2 (SARS-CoV-2) test results
Clinical characteristics of hospitalized patients with false-negative severe acute respiratory coronavirus virus 2 (SARS-CoV-2) test results Open
Objective: To determine clinical characteristics associated with false-negative severe acute respiratory coronavirus virus 2 (SARS-CoV-2) test results to help inform coronavirus disease 2019 (COVID-19) testing practices in the inpatient se…
View article: Radiation Therapy Combined with Cowpea Mosaic Virus Nanoparticle in Situ Vaccination Initiates Immune-Mediated Tumor Regression
Radiation Therapy Combined with Cowpea Mosaic Virus Nanoparticle in Situ Vaccination Initiates Immune-Mediated Tumor Regression Open
Epithelial ovarian cancer is a deadly gynecologic malignancy because of its late detection, usually after local and distant metastatic spread. These cancers develop resistance to traditional chemotherapeutic agents; therefore, the developm…
View article: Speciation of Phenanthriplatin and Its Analogs in the Core of Tobacco Mosaic Virus
Speciation of Phenanthriplatin and Its Analogs in the Core of Tobacco Mosaic Virus Open
Efficient loading of drugs in novel delivery agents has the potential to substantially improve therapy by targeting the diseased tissue while avoiding unwanted side effects. Here we report the first systematic study of the loading mechanis…
View article: Slow‐Release Formulation of Cowpea Mosaic Virus for In Situ Vaccine Delivery to Treat Ovarian Cancer
Slow‐Release Formulation of Cowpea Mosaic Virus for In Situ Vaccine Delivery to Treat Ovarian Cancer Open
The plant viral nanoparticle cowpea mosaic virus (CPMV) is shown to be an effective immunotherapy for ovarian cancer when administered as in situ vaccine weekly, directly into the intraperitoneal (IP) space in mice with disseminated tumors…
View article: Optical and Magnetic Resonance Imaging Using Fluorous Colloidal Nanoparticles
Optical and Magnetic Resonance Imaging Using Fluorous Colloidal Nanoparticles Open
Improved imaging of cancerous tissue has the potential to aid prognosis and improve patient outcome through longitudinal imaging of treatment response and disease progression. While nuclear imaging has made headway in cancer imaging, fluor…
View article: Tobacco Mosaic Virus Delivery of Phenanthriplatin for Cancer therapy
Tobacco Mosaic Virus Delivery of Phenanthriplatin for Cancer therapy Open
Phenanthriplatin, cis-[Pt(NH3)2Cl(phenanthridine)](NO3), is a cationic monofunctional DNA-binding platinum(II) anticancer drug candidate with unusual potency and cellular response profiles. Its in vivo efficacy has not yet been demonstrate…