Anna-Katharina Ehlert
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View article: Interaction of the gp120 V1V2 loop with a neighboring gp120 unit shields the HIV envelope trimer against cross-neutralizing antibodies
Interaction of the gp120 V1V2 loop with a neighboring gp120 unit shields the HIV envelope trimer against cross-neutralizing antibodies Open
The HIV-1 envelope trimer adopts a quaternary conformation that effectively shields neutralization-sensitive domains and thus represents a major obstacle for natural and vaccine-elicited antibody responses. By using a structure–function an…
View article: Th Cells Act Via Two Synergistic Pathways To Promote Antiviral CD8+ T Cell Responses
Th Cells Act Via Two Synergistic Pathways To Promote Antiviral CD8+ T Cell Responses Open
The mechanisms of how Th cells promote CD8+ T cell responses during viral infections are largely unknown. In this study, we unraveled the mechanisms of T cell help for CD8+ T cell responses during vaccinia virus infection. Our results demo…