Anna Hake
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Insights to HIV-1 coreceptor usage by estimating HLA adaptation with Bayesian generalized linear mixed models Open
The mechanisms triggering the human immunodeficiency virus type I (HIV-1) to switch the coreceptor usage from CCR5 to CXCR4 during the course of infection are not entirely understood. While low CD4 + T cell counts are associated with CXCR4…
View article: Dynamics and durability of HIV-1 neutralization are determined by viral replication
Dynamics and durability of HIV-1 neutralization are determined by viral replication Open
Human immunodeficiency virus type 1 (HIV-1)-neutralizing antibodies (nAbs) that prevent infection are the main goal of HIV vaccine discovery. But as no nAb-eliciting vaccines are yet available, only data from HIV-1 neutralizers—persons wit…
Consensus nucleotide sequences for env and gag for paper: Insights to HIV-1 coreceptor usage by estimating HLA adaptation with Bayesian generalized linear mixed models Open
This is the consensus sequence repository to the manuscript "Insights to HIV-1 coreceptor usage by estimating HLA adaptation with Bayesian generalized linear mixed models". It contains the 10% consensus nucleotide sequences of the env and …
Consensus nucleotide sequences for env and gag for paper: Insights to HIV-1 coreceptor usage by estimating HLA adaptation with Bayesian generalized linear mixed models Open
This is the consensus sequence repository to the manuscript "Insights to HIV-1 coreceptor usage by estimating HLA adaptation with Bayesian generalized linear mixed models". It contains the 10% consensus nucleotide sequences of the env and …
Insights to HIV-1 coreceptor usage by estimating HLA adaptation with Bayesian generalized linear mixed models Open
This is the data repository to the manuscript "Insights to HIV-1 coreceptor usage by estimating HLA adaptation with Bayesian generalized linear mixed models". It contains a minimal data set to reproduce all results that don't compromise th…
Insights to HIV-1 coreceptor usage by estimating HLA adaptation with Bayesian generalized linear mixed models Open
The mechanisms triggering the human immunodeficiency virus type I (HIV-1) to switch the coreceptor usage from CCR5 to CXCR4 during the course of infection are not entirely understood. While low CD4 + T cell counts are associated with CXCR4…
Minimal dataset for "Insights to HIV-1 coreceptor usage by estimating HLA adaptation with Bayesian generalized linear mixed models" Open
This repository contains a minimal data set to reproduce all results that don't compromise the privacy concerns for the manuscript "Insights to HIV-1 coreceptor usage by estimating HLA adaptation with Bayesian generalized linear mixed mode…
Minimal dataset for "Insights to HIV-1 coreceptor usage by estimating HLA adaptation with Bayesian generalized linear mixed models" Open
This repository contains a minimal data set to reproduce all results that don't compromise the privacy concerns for the manuscript "Insights to HIV-1 coreceptor usage by estimating HLA adaptation with Bayesian generalized linear mixed mode…
Prediction of HIV-1 sensitivity to broadly neutralizing antibodies shows a trend towards resistance over time Open
Treatment with broadly neutralizing antibodies (bNAbs) has proven effective against HIV-1 infections in humanized mice, non-human primates, and humans. Due to the high mutation rate of HIV-1, resistance testing of the patient's viral strai…