Bridget Holmes
YOU?
Author Swipe
View article: Prominent mediatory role of gut microbiome in the effect of lifestyle on host metabolic phenotypes
Prominent mediatory role of gut microbiome in the effect of lifestyle on host metabolic phenotypes Open
Lifestyle factors influence both gut microbiome composition and host metabolism, yet their combined and mediating effects on host phenotypes remain poorly characterized in cardiometabolic populations. In 1,643 participants from the MetaCar…
View article: Estimating the environmental impact of diets based on individual-level dietary intake data: infographics on the FAO/WHO GIFT platform
Estimating the environmental impact of diets based on individual-level dietary intake data: infographics on the FAO/WHO GIFT platform Open
Integrating environmental impacts into dietary assessment is crucial to promote healthy diets from sustainable food systems. Nonetheless, the environmental impacts of individual dietary intake are rarely reported. This paper describes how …
View article: A method to rapidly match environmental impact data to > 60 dietary datasets
A method to rapidly match environmental impact data to > 60 dietary datasets Open
There is growing interest in assessing the environmental impacts of diets due to the awareness of the link with human and planetary health. Until now, a limiting factor in this field has been linking information on the environmental impact…
View article: A gut microbiome-kidney-heart axis predictive of future cardiovascular diseases.
A gut microbiome-kidney-heart axis predictive of future cardiovascular diseases. Open
Cardiometabolic diseases (CMD) are on the rise globally with one billion people expected to suffer from obesity and 643 million from type 2 diabetes by 2030, of which one-third will likely develop chronic kidney disease and two-thirds will…
Concordance of Dietary Diversity and Moderation Among 28,787 Mother‐Child Dyads in 11 Low‐ and Middle‐Income Countries: Implications for Global Monitoring and Targeted Nutrition Actions Open
In 2025, the ‘Prevalence of minimum dietary diversity’ among infants and young children (IYC) aged 6–23 months and females aged 15–49 years was adopted as an additional Sustainable Development Goal 2: Zero Hunger indicator. Previous studie…
View article: Low-burden metrics for monitoring healthy diets across contexts: A multi-country validation analysis using quantitative 24-hour dietary intake data
Low-burden metrics for monitoring healthy diets across contexts: A multi-country validation analysis using quantitative 24-hour dietary intake data Open
Summary Background Unhealthy diets are a major public health concern. However, a lack of available and up-to-date quantitative dietary intake data, accurate low-burden data collection methods, and valid and interpretable metrics across con…
View article: Do lower antenatal blood pressure cut-offs in pregnant women with obesity identify those at greater risk of adverse maternal and perinatal outcomes? A secondary analysis of data from the UK Pregnancies Better Eating and Activity Trial (UPBEAT)
Do lower antenatal blood pressure cut-offs in pregnant women with obesity identify those at greater risk of adverse maternal and perinatal outcomes? A secondary analysis of data from the UK Pregnancies Better Eating and Activity Trial (UPBEAT) Open
Background Obesity is a major risk-factor for adverse pregnancy outcomes. While the 2017 American College of Cardiology/American Heart Association (ACC/AHA) classification of normal and abnormal blood pressure (BP) outside pregnancy has be…
Corrigendum: The influence of recipe disaggregation in dietary assessment: results from the national food consumption survey in Saint Kitts and Nevis Open
[This corrects the article DOI: 10.3389/fnut.2024.1404932.].
Minimum Dietary Diversity for Women: precision of national surveys and accuracy of brief data collection instruments Open
For global monitoring, standards must be defined for the preferred data collection instrument and survey platform for each healthy diet metric. This would facilitate cross-country comparability and help mitigate misinterpretations of chang…
View article: Opportunity Crop Indicators: Assessing the Climate Adaptation Potential of Opportunity Crops in Africa
Opportunity Crop Indicators: Assessing the Climate Adaptation Potential of Opportunity Crops in Africa Open
Global dependence on a few well-researched staple crops exacerbates systemic vulnerabilities to climate change and does not encourage bio- or dietary diversity. The Vision for Adapted Crops and Soils aims to strengthen African food systems…
View article: An open science framework and tools to create reproducible food composition data for use in nutrition
An open science framework and tools to create reproducible food composition data for use in nutrition Open
Food composition tables and databases (FCTs) and Nutrient Conversion Tables (NCTs) are essential for nutrition research. Compiling a new NCT requires multiple FCTs, usually with incompatible formats. FCT cleaning and standardisation is rar…
Cross-context equivalence and agreement of healthy diet metrics for national and global monitoring: a multicountry analysis of cross-sectional quantitative 24-hour dietary intake studies Open
Composite metrics weighting both healthy and unhealthy food groups have limited cross-context equivalence, because a wide range of diets can theoretically return similar scores. Healthy food group (sub)metrics performed comparably, likely …
The influence of recipe disaggregation in dietary assessment: results from the national food consumption survey in Saint Kitts and Nevis Open
It is not always the case that recipe disaggregation is performed in dietary surveys. This investigation aimed to assess the influence of recipe disaggregation in the 2020–2021 national dietary survey in Saint Kitts and Nevis, and provide …
Minimum Dietary Diversity for Adolescents: Multicountry Analysis to Define Food Group Thresholds Predicting Micronutrient Adequacy among Girls and Boys Aged 10–19 Years Open
MDD-W can be extended to boys and girls aged 10-19 y from upper-middle and high-income countries. Furthermore, an adapted indicator using a ≥4 food group threshold signals higher micronutrient adequacy in low and lower-middle-income countr…
The Gut Microbiome Strongly Mediates the impact of Lifestyle combined variables on Cardiometabolic Phenotypes Open
Individual lifestyle factors moderately impact the gut microbiome and host biology. This study explores whether their combined influence significantly alters the gut microbiome and determines the mediating role of the gut microbiome in the…
Harmonising dietary datasets for global surveillance: methods and findings from the Global Dietary Database Open
Objective: The Global Dietary Database (GDD) expanded its previous methods to harmonise and publicly disseminate individual-level dietary data from nutrition surveys worldwide. Design: Analysis of cross-sectional data. Setting: Global. Par…
View article: Healthy diet metrics: a suitability assessment of indicators for global and national monitoring purposes
Healthy diet metrics: a suitability assessment of indicators for global and national monitoring purposes Open
Diets are changing everywhere, and the burden of disease associated with unhealthy diets is a worldwide concern. Measurement and monitoring of diets across countries and population groups is critical. However, there are no harmonized metri…
View article: Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine<i>N</i>-oxide with implications for heart and kidney disorders
Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine<i>N</i>-oxide with implications for heart and kidney disorders Open
Objectives The host-microbiota co-metabolite trimethylamine N -oxide (TMAO) is linked to increased thrombotic and cardiovascular risks. Here we, sought to i) characterize which host variables contribute to fasting serum TMAO levels in real…
View article: Comparison of databases reporting nutrient measures of fish and other aquatic foods
Comparison of databases reporting nutrient measures of fish and other aquatic foods Open
The nutrition values of fish and other aquatic foods have recently gained global recognition for their potential to alleviate ‘hidden hunger’ in many contexts and for many nutritional vulnerable people. Yet, data for most fish, aquatic spe…
Lifestyle intervention in obese pregnancy and cardiac remodelling in 3-year olds: children of the UPBEAT RCT Open
Background/Objectives Obesity in pregnancy has been associated with increased childhood cardiometabolic risk and reduced life expectancy. The UK UPBEAT multicentre randomised control trial was a lifestyle intervention of diet and physical …
View article: Global Trends in the Availability of Dietary Data in Low and Middle-Income Countries
Global Trends in the Availability of Dietary Data in Low and Middle-Income Countries Open
Individual-level quantitative dietary data can provide suitably disaggregated information to identify the needs of all population sub-groups, which can in turn inform agricultural, nutrition, food safety, and environmental policies and pro…
View article: Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism Open
Objectives Gut microbiota is a key component in obesity and type 2 diabetes, yet mechanisms and metabolites central to this interaction remain unclear. We examined the human gut microbiome’s functional composition in healthy metabolic stat…
View article: The Habitual Diet of Dutch Adult Patients with Eosinophilic Esophagitis Has Pro-Inflammatory Properties and Low Diet Quality Scores
The Habitual Diet of Dutch Adult Patients with Eosinophilic Esophagitis Has Pro-Inflammatory Properties and Low Diet Quality Scores Open
We determined the nutritional adequacy and overall quality of the diets of adult patients with eosinophilic esophagitis (EoE). Dietary intakes stratified by sex and age were compared to Dietary Reference Values (DRV). Overall diet quality …