Anna Kerpel-Fronius
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View article: Alpha1-Antitrypsin in Lung Diseases: A Cross-Sectional Observational Study
Alpha1-Antitrypsin in Lung Diseases: A Cross-Sectional Observational Study Open
Major mutations of SERPINA1, the gene encoding alpha1-antitrypsin (A1AT), are known to cause severe emphysema. Our study aimed to investigate the role of major mutations modulating A1AT levels in several lung pathologies and control groups…
View article: Guidance for chest-CT in children and adults with cystic fibrosis: A European perspective
Guidance for chest-CT in children and adults with cystic fibrosis: A European perspective Open
The European Cystic Fibrosis Society-Clinical Trials Network (ECFS-CTN) herein proposes guidance for the use of chest CT-scans for the regular monitoring of lung disease in CF. Statements were completed in a 3-step process: the questions w…
View article: Lung Cancer Screening Program Quality Indicators—Review and Recommendations: An International Association for the Study of Lung Cancer Delphi Process Study
Lung Cancer Screening Program Quality Indicators—Review and Recommendations: An International Association for the Study of Lung Cancer Delphi Process Study Open
A review among panel members provided recommended LCS QIs that should be considered in the development of LCS initiatives.
View article: Machine Learning-enhanced X-ray-based Radiomics in the Identification of Post-COVID Patients
Machine Learning-enhanced X-ray-based Radiomics in the Identification of Post-COVID Patients Open
View article: Economic evaluation of low-dose computed tomography for lung cancer screening among high-risk individuals – evidence from Hungary based on the HUNCHEST-II study
Economic evaluation of low-dose computed tomography for lung cancer screening among high-risk individuals – evidence from Hungary based on the HUNCHEST-II study Open
View article: Decreasing incidence and mortality of lung cancer in Hungary between 2011 and 2021 revealed by robust estimates reconciling multiple data sources
Decreasing incidence and mortality of lung cancer in Hungary between 2011 and 2021 revealed by robust estimates reconciling multiple data sources Open
Objective Hungary has repeatedly been shown to have the highest cancer-related mortality and incidence in Europe. Despite lung cancer being the most abundant malignant diagnosis in Hungary, numerous concerns have been raised recently regar…
View article: Economic Evaluation of Low-Dose Computed Tomography for Lung Cancer Screening among High- Risk Individuals – Evidence from Hungary Based on the HUNCHEST-II study
Economic Evaluation of Low-Dose Computed Tomography for Lung Cancer Screening among High- Risk Individuals – Evidence from Hungary Based on the HUNCHEST-II study Open
Background Lung cancer (LC) is the leading cause of cancer-related death in Hungary. Early diagnosis of LC contributes to delivering survival benefits to patients. Low-dose computer tomography (LDCT) is an imaging technology that can be us…
View article: HUNCHEST projects—advancing low-dose CT lung cancer screening in Hungary
HUNCHEST projects—advancing low-dose CT lung cancer screening in Hungary Open
Lung cancer, the leading cause of malignancy-related deaths worldwide, demands proactive measures to mitigate its impact. Low-dose computer tomography (LDCT) has emerged as a promising tool for secondary prevention through lung cancer scre…
View article: Perspective on Management of Low-Dose Computed Tomography Findings on Low-Dose Computed Tomography Examinations for Lung Cancer Screening. From the International Association for the Study of Lung Cancer Early Detection and Screening Committee
Perspective on Management of Low-Dose Computed Tomography Findings on Low-Dose Computed Tomography Examinations for Lung Cancer Screening. From the International Association for the Study of Lung Cancer Early Detection and Screening Committee Open
View article: HUNCHEST-II contributes to a shift to earlier-stage lung cancer detection: final results of a nationwide screening program
HUNCHEST-II contributes to a shift to earlier-stage lung cancer detection: final results of a nationwide screening program Open
View article: P1.17-01 Lung Cancer Screening in Low- and Middle-income Countries - Report on Status, Challenges and Perspectives from WCLC2022 and LALCA2023
P1.17-01 Lung Cancer Screening in Low- and Middle-income Countries - Report on Status, Challenges and Perspectives from WCLC2022 and LALCA2023 Open
View article: Computed Tomography-Based Quantitative Texture Analysis and Gut Microbial Community Signatures Predict Survival in Non-Small Cell Lung Cancer
Computed Tomography-Based Quantitative Texture Analysis and Gut Microbial Community Signatures Predict Survival in Non-Small Cell Lung Cancer Open
This study aims to combine computed tomography (CT)-based texture analysis (QTA) and a microbiome-based biomarker signature to predict the overall survival (OS) of immune checkpoint inhibitor (ICI)-treated non-small cell lung cancer (NSCLC…
View article: Significant changes in advanced lung cancer survival during the past decade in Hungary: impact of modern immunotherapy and the COVID-19 pandemic
Significant changes in advanced lung cancer survival during the past decade in Hungary: impact of modern immunotherapy and the COVID-19 pandemic Open
Objective The approval of immunotherapy (I-O) for the treatment of late-stage non-small cell lung cancer (NSCLC) opened new perspectives in improving survival outcomes. However, survival data have not yet been provided from the period of t…
View article: ERS/ESTS/ESTRO/ESR/ESTI/EFOMP statement on management of incidental findings from low dose CT screening for lung cancer
ERS/ESTS/ESTRO/ESR/ESTI/EFOMP statement on management of incidental findings from low dose CT screening for lung cancer Open
Background Screening for lung cancer with low radiation dose computed tomography has a strong evidence base, is being introduced in several European countries and is recommended as a new targeted cancer screening programme. The imperative …
View article: ERS/ESTS/ESTRO/ESR/ESTI/EFOMP statement on management of incidental findings from low dose CT screening for lung cancer
ERS/ESTS/ESTRO/ESR/ESTI/EFOMP statement on management of incidental findings from low dose CT screening for lung cancer Open
Background Screening for lung cancer with low radiation dose computed tomography has a strong evidence base, is being introduced in several European countries and is recommended as a new targeted cancer screening programme. The imperative …
View article: Developing a pan-European technical standard for a comprehensive high-quality lung cancer computed tomography screening programme: an ERS technical standard
Developing a pan-European technical standard for a comprehensive high-quality lung cancer computed tomography screening programme: an ERS technical standard Open
Background Screening for lung cancer with low radiation dose computed tomography (LDCT) has a strong evidence base. The European Council adopted a recommendation in November 2022 that lung cancer screening (LCS) be implemented using a step…
View article: Table of Contents
Table of Contents Open
View article: Shall We Screen Lung Cancer With Low-Dose Computed Tomography? Cost-Effectiveness in Hungary
Shall We Screen Lung Cancer With Low-Dose Computed Tomography? Cost-Effectiveness in Hungary Open
View article: Lung Cancer Screening Considerations During Respiratory Infection Outbreaks, Epidemics or Pandemics: An International Association for the Study of Lung Cancer Early Detection and Screening Committee Report
Lung Cancer Screening Considerations During Respiratory Infection Outbreaks, Epidemics or Pandemics: An International Association for the Study of Lung Cancer Early Detection and Screening Committee Report Open
View article: Screening for Lung Cancer in Individuals Who Never Smoked: An International Association for the Study of Lung Cancer Early Detection and Screening Committee Report
Screening for Lung Cancer in Individuals Who Never Smoked: An International Association for the Study of Lung Cancer Early Detection and Screening Committee Report Open
View article: A kis dózisú komputertomográfiával történő tüdőrákszűrés költségvetési hatása
A kis dózisú komputertomográfiával történő tüdőrákszűrés költségvetési hatása Open
Összefoglaló. Bevezetés: Korábbi vizsgálatunk szerint a kis dózisú komputertomográfiával évente végzett tüdőrákszűrés 50–74 éves dohányzók körében költséghatékony, és az 55–74 évesek körében költségmegtakarító. Célkitűzés: Ennek a vizsgála…
View article: Cost-effectiveness analysis of low-dose computed tomography screening for lung cancer in Hungary
Cost-effectiveness analysis of low-dose computed tomography screening for lung cancer in Hungary Open
Background Hungary has the highest incidence of lung cancer in the world (GLOBOCAN, 2018). Since lung cancer is rarely treatable in its advanced stage, one possible way to reduce mortality is early diagnosis and subsequent treatment. The p…
View article: P1.04-49 Quantitative Computed Tomography (CT) Based Texture Analysis (QTA) Might Identify Responders to Immunotherapy in Non-Small Cell Lung Cancer
P1.04-49 Quantitative Computed Tomography (CT) Based Texture Analysis (QTA) Might Identify Responders to Immunotherapy in Non-Small Cell Lung Cancer Open