Anna M. Ray
YOU?
Author Swipe
View article: Evidence for an association between prostate cancer and chromosome 8q24 and 10q11 genetic variants in African American men: The flint men's health study
Evidence for an association between prostate cancer and chromosome 8q24 and 10q11 genetic variants in African American men: The flint men's health study Open
Prostate cancer is the most commonly diagnosed non-skin cancer in men in the United States and the second leading cause of cancer-related mortality. African American men have substantially increased risk of both being diagnosed and dying f…
View article: Germline Mutations in HOXB13 and Prostate-Cancer Risk
Germline Mutations in HOXB13 and Prostate-Cancer Risk Open
Family history is a significant risk factor for prostate cancer, although the molecular basis for this association is poorly understood. Linkage studies have implicated chromosome 17q21-22 as a possible location of a prostate-cancer suscep…
View article: Analysis of the gene coding for the BRCA2-Interacting protein PALB2 in hereditary prostate cancer
Analysis of the gene coding for the BRCA2-Interacting protein PALB2 in hereditary prostate cancer Open
The genetic basis of susceptibility to prostate cancer (PRCA) remains elusive. Mutations in BRCA2 have been associated with increased prostate cancer risk and account for around 2% of young onset (<56 years) prostate cancer cases. PALB2 is…
View article: Genetic polymorphisms inCYP17,CYP3A4,CYP19A1,SRD5A2,IGF-1, andIGFBP-3 and prostate cancer risk in African-American men: The Flint Men's Health Study
Genetic polymorphisms inCYP17,CYP3A4,CYP19A1,SRD5A2,IGF-1, andIGFBP-3 and prostate cancer risk in African-American men: The Flint Men's Health Study Open
Association studies have examined the significance of several candidate genes based on biological pathways relevant to prostate carcinogenesis, including both the androgen and insulin-like growth factor pathways. Clinical and epidemiologic…
View article: Early onset prostate cancer has a significant genetic component
Early onset prostate cancer has a significant genetic component Open
Prostate cancer (PCa) affects more than 190,000 men each year with ~10% of men diagnosed at ≤ 55 years, i.e., early onset (EO) PCa. Based on historical findings for other cancers, EO PCa likely reflects a stronger underlying genetic etiolo…
View article: Genome-wide linkage scan for prostate cancer susceptibility from the university of michigan prostate cancer genetics project: Suggestive evidence for linkage at 16q23
Genome-wide linkage scan for prostate cancer susceptibility from the university of michigan prostate cancer genetics project: Suggestive evidence for linkage at 16q23 Open
Prostate cancer linkage studies have been used to localize rare and presumably highly penetrant cancer susceptibility genes. Underlying genetic heterogeneity, as well as the high sporadic background of the disease, has resulted in many sig…
View article: The androgen receptor CAG and GGN repeat polymorphisms and prostate cancer susceptibility in African-American men: results from the Flint Men’s Health Study
The androgen receptor CAG and GGN repeat polymorphisms and prostate cancer susceptibility in African-American men: results from the Flint Men’s Health Study Open
Repeat lengths of the CAG and GGN micro-satellites in exon 1 of the androgen receptor (AR) gene have been hypothesized to be associated with prostate cancer risk. In vitro studies have showed an inverse association between AR CAG and GGN r…
View article: Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: evidence from the International Consortium for Prostate Cancer Genetics (ICPCG)
Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: evidence from the International Consortium for Prostate Cancer Genetics (ICPCG) Open
Multiple prostate cancer (PCa) risk-related loci have been discovered by genome-wide association studies (GWAS) based on case–control designs. However, GWAS findings may be confounded by population stratification if cases and controls are …
View article: Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease
Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease Open
Previous GWAS studies have reported significant associations between various common SNPs and prostate cancer risk using cases unselected for family history. How these variants influence risk in familial prostate cancer is not well studied.…
View article: Common Variation in the BRCA1 Gene and Prostate Cancer Risk
Common Variation in the BRCA1 Gene and Prostate Cancer Risk Open
Rare, inactivating mutations in the BRCA1 gene appear to play a limited role in prostate cancer. To our knowledge, however, no study has comprehensively assessed the role of other BRCA1 sequence variations, e.g., missense mutations, in pro…
View article: Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21
Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21 Open
Previous genome-wide association studies (GWAS) of prostate cancer risk focused on cases unselected for family history and have reported over 100 significant associations. The International Consortium for Prostate Cancer Genetics (ICPCG) h…
View article: Anti-cancer effects of aloe-emodin: a systematic review
Anti-cancer effects of aloe-emodin: a systematic review Open
Cancer patients often utilize alternative therapies as a result of suboptimal efficacy of conventional treatments. Aloe-emodin might become a therapeutic option for cancer patients if the basic research is confirmed in clinical trials.
View article: The effect of exercise training on disease progression, fitness, quality of life, and mental health in people living with HIV on ART: a systematic review
The effect of exercise training on disease progression, fitness, quality of life, and mental health in people living with HIV on ART: a systematic review Open
Background: Exercise has been associated with improvements in adverse physiological and psychological effects of long-term antiretroviral therapy (ART) in people living with HIV (PLWH).Aim: To summarizes the findings on the effects of aero…