Anna McCormick
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View article: Environmental genomic selection to leverage polygenic local adaptation in barley landraces
Environmental genomic selection to leverage polygenic local adaptation in barley landraces Open
Climate change is threatening agricultural production across the globe. Germplasm collections provide an opportunity to explore where variation exists with important crop species. Genome environment association (GEA) is a standard approach…
View article: Species distribution of Cannabis sativa: Past, present and future
Species distribution of Cannabis sativa: Past, present and future Open
Cannabis sativa L. is an annual flowering herb of Eurasian origin that has long been associated with humans. Domesticated independently at multiple locations at different times for different purposes (food, fiber, and medicine), these long…
View article: Uncovering genetic linkages in the rhizosphere contributing to adaptation
Uncovering genetic linkages in the rhizosphere contributing to adaptation Open
Microorganisms assembled into the plant rhizosphere from the surrounding soil can benefit the fitness of their host. Variation in plant genetics is associated with variation in rhizosphere microbial community composition leading to increas…
View article: Back to the Future: Environmental genomic selection to take advantage of polygenic local adaptation
Back to the Future: Environmental genomic selection to take advantage of polygenic local adaptation Open
The genetic basis of adaptation is a fundamental question in evolutionary genetics. Environmental association analysis (EAA) and various allele frequency comparisons in genomic environmental association (GEA) have become standard approache…
View article: Can we do better supporting young adults with cerebral palsy as they navigate adulthood? A review of current and future transitional practices
Can we do better supporting young adults with cerebral palsy as they navigate adulthood? A review of current and future transitional practices Open
OBJECTIVE Patients with cerebral palsy (CP) face lifelong consequences of their condition, and their healthcare needs evolve as they age. Transitional care for these patients is not universally available and various models have been descri…
View article: Evaluating Sweetpotato Varieties and Accessions in Hawai‘i
Evaluating Sweetpotato Varieties and Accessions in Hawai‘i Open
Thirty sweetpotato ( Ipomoea batatas var. batatas ) genotypes were evaluated for yield, resistances to weevil or nematode pests, and consumer acceptance across three field trials planted at Pepe‘ekeo, Hawai‘i Island between 2017 to 2020. A…
View article: Species Distribution of<i>Cannabis sativa</i>: Past, Present and future
Species Distribution of<i>Cannabis sativa</i>: Past, Present and future Open
Cannabis sativa L. is an annual flowering herb of Eurasian origin that has long been associated with humans. Domesticated independently at multiple locations at different times for different purposes (food, fiber, and medicine), these long…
View article: Climate resilience conserved in global germplasm repositories: Picking the most promising parents for agile plant breeding
Climate resilience conserved in global germplasm repositories: Picking the most promising parents for agile plant breeding Open
Crop diversity is an essential resource for national and international breeding programs aimed at preparing global agriculture for a changing climate to ensure global food security. To do this there are related risks that need to be evalua…
View article: The Clinical Development of Taldefgrobep Alfa: An Anti-Myostatin Adnectin for the Treatment of Duchenne Muscular Dystrophy
The Clinical Development of Taldefgrobep Alfa: An Anti-Myostatin Adnectin for the Treatment of Duchenne Muscular Dystrophy Open
NCT02145234, NCT02515669, NCT03039686.
View article: Impacting Children’s Physical and Mental Health through Kinesiology Support in Clinical Care: A Randomized Controlled Trial Protocol
Impacting Children’s Physical and Mental Health through Kinesiology Support in Clinical Care: A Randomized Controlled Trial Protocol Open
Objectives: To enhance the confidence of children and adolescents with medical conditions and disabilities to engage in healthy, active lifestyles. Children with medical conditions and disabilities often exhibit more sedentary lifestyles r…
View article: P.076 Tone management: an environmental scan of current management practices across Canada
P.076 Tone management: an environmental scan of current management practices across Canada Open
Background: Currently, there are no standardized approaches to care or evaluation for tone dysfunction in Canada. The study authors hypothesize that there is significant practice variation across the country. This environmental scan is aim…
View article: Population structure in diverse pepper (Capsicum spp.) accessions
Population structure in diverse pepper (Capsicum spp.) accessions Open
This data represents genotypes of a pepper diversity collection. Samples were sequenced using double-digest Genotyping-By-Sequencing (GBS) using Apek1 and Btg1 restriction enzymes. Fastq files were demultiplexed using Illumina bcl2fastq so…
View article: Population structure in diverse pepper (Capsicum spp.) accessions
Population structure in diverse pepper (Capsicum spp.) accessions Open
This data represents genotypes of a pepper diversity collection. Samples were sequenced using double-digest Genotyping-By-Sequencing (GBS) using Apek1 and Btg1 restriction enzymes. Fastq files were demultiplexed using Illumina bcl2fastq so…
View article: Examining population structure across multiple collections of Cannabis
Examining population structure across multiple collections of Cannabis Open
Population structure of Cannabis sativa L. was explored across nine independent collections that each contained a unique sampling of varieties. Hierarchical Clustering of Principal Components (HCPC) identified a range of three to seven gen…
View article: Prioritizing a Research Agenda of Transitional Care Interventions for Childhood-Onset Disabilities
Prioritizing a Research Agenda of Transitional Care Interventions for Childhood-Onset Disabilities Open
Transitional care interventions have the potential to optimize continuity of care, improve health outcomes and enhance quality of life for adolescents and young adults living with chronic childhood-onset disabilities, including neurodevelo…
View article: The heterogeneity of the DNA damage response landscape determines patient outcomes in ovarian cancer
The heterogeneity of the DNA damage response landscape determines patient outcomes in ovarian cancer Open
Defective DNA damage response (DDR) pathways allow cancer cells to accrue genomic aberrations and evade normal cellular growth checkpoints. Defective DDR also determines response to chemotherapy. However, the interaction and overlap betwee…
View article: Neurodevelopmental profiles of children with unilateral cerebral palsy associated with middle cerebral artery and periventricular venous infarctions
Neurodevelopmental profiles of children with unilateral cerebral palsy associated with middle cerebral artery and periventricular venous infarctions Open
Aim To compare the neurodevelopment of children with unilateral cerebral palsy (CP) with middle cerebral artery (MCA) and periventricular venous infarctions (PVIs). Method In this cross‐sectional study, children with unilateral CP complete…
View article: Mindfulness-based interventions for children and adolescents across all settings: a scoping review protocol
Mindfulness-based interventions for children and adolescents across all settings: a scoping review protocol Open
Background and purpose Although mindfulness-based interventions (MBIs) are becoming increasingly popular, the application of MBIs with children and adolescents is still in its infancy. Mapping the existing literature is necessary to help g…
View article: Mindfulness-based interventions for children and adolescents across all settings: A scoping review protocol
Mindfulness-based interventions for children and adolescents across all settings: A scoping review protocol Open
Background and purpose: Although mindfulness-based interventions (MBIs) are becoming increasingly popular, the application of MBIs with children and adolescents is still in its infancy. Mapping the existing literature is necessary to help …
View article: Mindfulness-based interventions for children and adolescents across all settings: A scoping review protocol
Mindfulness-based interventions for children and adolescents across all settings: A scoping review protocol Open
Background and purpose: Although mindfulness-based interventions (MBIs) are becoming increasingly popular, the application of MBIs with children and adolescents is still in its infancy. Mapping the existing literature is necessary to help …
View article: The Canadian Neuromuscular Disease Registry 2010–2019: A Decade of Facilitating Clinical Research Througha Nationwide, Pan-NeuromuscularDisease Registry
The Canadian Neuromuscular Disease Registry 2010–2019: A Decade of Facilitating Clinical Research Througha Nationwide, Pan-NeuromuscularDisease Registry Open
We report the recruitment activities and outcomes of a multi-disease neuromuscular patient registry in Canada. The Canadian Neuromuscular Disease Registry (CNDR) registers individuals across Canada with a confirmed diagnosis of a neuromusc…
View article: A National Spinal Muscular Atrophy Registry for Real-World Evidence
A National Spinal Muscular Atrophy Registry for Real-World Evidence Open
Background: Spinal muscular atrophy (SMA) is a devastating rare disease that affects individuals regardless of ethnicity, gender, and age. The first-approved disease-modifying therapy for SMA, nusinursen, was approved by Health Canada, as …
View article: Mindfulness-based interventions for children and adolescents: A scoping review protocol
Mindfulness-based interventions for children and adolescents: A scoping review protocol Open
Background and purpose: Although mindfulness-based interventions (MBIs) are becoming increasingly popular, the application of MBIs with children and adolescents is still in its infancy. Mapping the existing literature is necessary to help …
View article: Robotic Walkers for Children and Youth with Cerebral Palsy: A Review of Past Successes and Ongoing Advancement
Robotic Walkers for Children and Youth with Cerebral Palsy: A Review of Past Successes and Ongoing Advancement Open
Each child with a disability deserves the support required to achieve their maximum physical potential, optimal participation and an active lifestyle throughout their lifespan.In this paper, we aim to highlight past successes, present work…
View article: 95 A Comparison of the Developmental Profiles of Individuals with Hemiplegic Cerebral Palsy associated with Middle Cerebral Artery and Periventricular Venous Infarctions
95 A Comparison of the Developmental Profiles of Individuals with Hemiplegic Cerebral Palsy associated with Middle Cerebral Artery and Periventricular Venous Infarctions Open
BACKGROUND: We lack knowledge of the developmental profiles of different brain injuries in hemiplegic cerebral palsy (HCP). This is important because children with specific injury patterns may respond differently to rehabilitation interven…