Anna Monistrol-Mula
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View article: The Role of Genetic Data in Dissecting Depression Heterogeneity
The Role of Genetic Data in Dissecting Depression Heterogeneity Open
Depression is a highly prevalent and disabling condition, with its burden expected to rise significantly by 2050. The heterogeneity of depression is evident in the wide variation of symptom presentations and comorbidities, complicating eff…
View article: Co-RESPOND: a federated network of cohorts on mental health and adversity during the COVID-19 pandemic. Challenges, solutions and recommendations for retrospective data harmonization
Co-RESPOND: a federated network of cohorts on mental health and adversity during the COVID-19 pandemic. Challenges, solutions and recommendations for retrospective data harmonization Open
Background: The SARS-Cov-2 pandemic was associated with a substantial rise in trauma and stressor exposure. The Co-RESPOND consortium (part of the EU horizon 2020-funded RESPOND project) has been initiated to study the impact on men…
View article: Psychological distress and compliance with sanitary measures during the Covid-19 pandemic
Psychological distress and compliance with sanitary measures during the Covid-19 pandemic Open
Background This study aims to understand the relationship between the experience of psychological distress and compliance with COVID-19 sanitary measures. We testeed whether this relationship was modified by individuals’ gender and socioec…
View article: Specialized mental healthcare use for common mental disorders and prescription of antidepressants before and during the COVID-19 pandemic among working-age refugees and Swedish-born individuals – a nationwide register-based study
Specialized mental healthcare use for common mental disorders and prescription of antidepressants before and during the COVID-19 pandemic among working-age refugees and Swedish-born individuals – a nationwide register-based study Open
View article: Psychological distress and compliance with sanitary measures during the Covid-19 pandemic: effect modification by participant gender and socioeconomic characteristics, an IPD meta-analysis.
Psychological distress and compliance with sanitary measures during the Covid-19 pandemic: effect modification by participant gender and socioeconomic characteristics, an IPD meta-analysis. Open
Background: This study aims to understand how individuals’ psychological distress is related to compliance with COVID-19 sanitary measures. In addition, we explored whether gender and socioeconomic status (i.e educational level and employm…
View article: Identifying psychiatric morbidity and comorbidity patterns associated with COVID-19 mortality. A register-based cohort study from Catalonia
Identifying psychiatric morbidity and comorbidity patterns associated with COVID-19 mortality. A register-based cohort study from Catalonia Open
Background There is limited evidence on the association between psychiatric morbidity and COVID-19 mortality. Methods We used deidentified electronic health records from the Catalan public health system to evaluate the association between …
View article: SARS-CoV-2 infection and COVID-19 outcomes across mental disorders and the role of sex: A register-based study from Catalonia
SARS-CoV-2 infection and COVID-19 outcomes across mental disorders and the role of sex: A register-based study from Catalonia Open
View article: The effect of polygenic liability to mental disorders on COVID-19 outcomes in people with depression: the mediating role of anxiety
The effect of polygenic liability to mental disorders on COVID-19 outcomes in people with depression: the mediating role of anxiety Open
Background Genetic vulnerability to mental disorders has been associated with coronavirus disease-19 (COVID-19) outcomes. We explored whether polygenic risk scores (PRSs) for several mental disorders predicted poorer clinical and psycholog…
View article: Long-Term Emotional Impact of the COVID-19 Pandemic and Barriers and Facilitators to Digital Mental Health Tools in Long-Term Care Workers: Qualitative Study
Long-Term Emotional Impact of the COVID-19 Pandemic and Barriers and Facilitators to Digital Mental Health Tools in Long-Term Care Workers: Qualitative Study Open
Background The overall pandemic created enormous pressure on long-term care workers (LTCWs), making them particularly vulnerable to mental disorders. Despite this, most of the available evidence on professional well-being during COVID-19 h…
View article: Association between tuberculosis and psychotic experiences: Mediating factors and implications for patient care in low- and middle-income countries
Association between tuberculosis and psychotic experiences: Mediating factors and implications for patient care in low- and middle-income countries Open
Tuberculosis was associated with increased odds of PEs. Factors such as affect, sleep, and pain should be considered in tuberculosis patients to target those who might be particularly vulnerable to PEs, and consequently, to psychotic disor…
View article: Genetic analyses point to alterations in immune-related pathways underpinning the association between psychiatric disorders and COVID-19
Genetic analyses point to alterations in immune-related pathways underpinning the association between psychiatric disorders and COVID-19 Open
Current literature suggests that people with psychiatric disorders have higher risk of SARS-CoV-2 infection and a worse prognosis of the disease. We aimed to study the genetic contribution to these associations in a range of psychiatric di…
View article: Beyond effectiveness in eHealth trials: Process evaluation of a stepped-care programme to support healthcare workers with psychological distress (RESPOND-HCWs)
Beyond effectiveness in eHealth trials: Process evaluation of a stepped-care programme to support healthcare workers with psychological distress (RESPOND-HCWs) Open
Objectives This study presents the process evaluation of an effective stepped-care programme of eHealth interventions (Doing What Matters in Times of Stress [DWM] and Problem Management Plus [PM+]) for healthcare workers (HCWs) with psycho…
View article: Effectiveness of a mental health stepped-care programme for healthcare workers with psychological distress in crisis settings: a multicentre randomised controlled trial
Effectiveness of a mental health stepped-care programme for healthcare workers with psychological distress in crisis settings: a multicentre randomised controlled trial Open
Background Evidence-based mental health interventions to support healthcare workers (HCWs) in crisis settings are scarce. Objective To evaluate the capacity of a mental health intervention in reducing anxiety and depression symptoms in HCW…
View article: Mental health symptoms 1 year after the COVID-19 outbreak in Spain: The role of pre-existing mental disorders and their type
Mental health symptoms 1 year after the COVID-19 outbreak in Spain: The role of pre-existing mental disorders and their type Open
View article: Mental health problems and needs of frontline healthcare workers during the COVID-19 pandemic in Spain: A qualitative analysis
Mental health problems and needs of frontline healthcare workers during the COVID-19 pandemic in Spain: A qualitative analysis Open
Background Healthcare workers (HCWs) from COVID-19 hotspots worldwide have reported poor mental health outcomes since the pandemic's beginning. The virulence of the initial COVID-19 surge in Spain and the urgency for rapid evidence constra…
View article: Methods for Stratification and Validation Cohorts: A Scoping Review
Methods for Stratification and Validation Cohorts: A Scoping Review Open
Personalized medicine requires large cohorts for patient stratification and validation of patient clustering. However, standards and harmonized practices on the methods and tools to be used for the design and management of cohorts in perso…
View article: Dataset Methods for stratification and validation cohorts: a scoping review
Dataset Methods for stratification and validation cohorts: a scoping review Open
We searched PubMed, EMBASE and the Cochrane Library for reviews that described the tools and methods applied to define cohorts used for patient stratification or validation of patient clustering. We focused on cancer, stroke, and Alzheimer…
View article: Dataset Methods for stratification and validation cohorts: a scoping review
Dataset Methods for stratification and validation cohorts: a scoping review Open
We searched PubMed, EMBASE and the Cochrane Library for reviews that described the tools and methods applied to define cohorts used for patient stratification or validation of patient clustering. We focused on cancer, stroke, and Alzheimer…
View article: The impact of COVID-related perceived stress and social support on generalized anxiety and major depressive disorders: moderating effects of pre-pandemic mental disorders
The impact of COVID-related perceived stress and social support on generalized anxiety and major depressive disorders: moderating effects of pre-pandemic mental disorders Open
View article: Effectiveness of a stepped-care programme of internet-based psychological interventions for healthcare workers with psychological distress: Study protocol for the RESPOND healthcare workers randomised controlled trial
Effectiveness of a stepped-care programme of internet-based psychological interventions for healthcare workers with psychological distress: Study protocol for the RESPOND healthcare workers randomised controlled trial Open
Background and aims The coronavirus disease 2019 pandemic has challenged health services worldwide, with a worsening of healthcare workers’ mental health within initial pandemic hotspots. In early 2022, the Omicron variant is spreading rap…
View article: A systematic literature review of prognostic factors in patients with HR+/HER2− advanced breast cancer in Japan
A systematic literature review of prognostic factors in patients with HR+/HER2− advanced breast cancer in Japan Open
Background Breast cancer is the most prevalent cancer in women in Japan and the fifth in mortality. This systematic review summarized the evidence for prognostic factors for patients with HR+/HER2− advanced and metastatic breast cancer in …
View article: Nutrition, Bioenergetics, and Metabolic Syndrome
Nutrition, Bioenergetics, and Metabolic Syndrome Open
According to the World Health Organization (WHO), the global nutrition report shows that whilst part of the world’s population starves, the other part suffers from obesity and associated complications. A balanced diet counterparts these ex…
View article: Common and rare variants of WNT16, DKK1 and SOST and their relationship with bone mineral density
Common and rare variants of WNT16, DKK1 and SOST and their relationship with bone mineral density Open