Anna Nolan
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View article: Gastroesophageal disease risk and inhalational exposure a systematic review and meta-analysis
Gastroesophageal disease risk and inhalational exposure a systematic review and meta-analysis Open
Environmental exposure-associated diseases, particularly in the context of rising air pollution and inhalant use, are an active area of research. Our group is dedicated to the study of exposure-related inflammation and its downstream adver…
View article: Interstitial Lung Disease and Progressive Pulmonary Fibrosis: a World Trade Center Cohort 20-Year Longitudinal Study
Interstitial Lung Disease and Progressive Pulmonary Fibrosis: a World Trade Center Cohort 20-Year Longitudinal Study Open
Purpose World Trade Center (WTC) exposure is associated with obstructive airway diseases and sarcoidosis. There is limited research regarding the incidence and progression of non-sarcoidosis interstitial lung diseases (ILD) after WTC-expos…
View article: Correction: Podury et al. Severe Acute Respiratory Syndrome and Particulate Matter Exposure: A Systematic Review. Life 2023, 13, 538
Correction: Podury et al. Severe Acute Respiratory Syndrome and Particulate Matter Exposure: A Systematic Review. Life 2023, 13, 538 Open
In the original publication [...]
View article: Resistin-like Molecule α and Pulmonary Vascular Remodeling: A Multi-Strain Murine Model of Antigen and Urban Ambient Particulate Matter Co-Exposure
Resistin-like Molecule α and Pulmonary Vascular Remodeling: A Multi-Strain Murine Model of Antigen and Urban Ambient Particulate Matter Co-Exposure Open
Pulmonary hypertension (PH) has a high mortality and few treatment options. Adaptive immune mediators of PH in mice challenged with antigen/particulate matter (antigen/PM) has been the focus of our prior work. We identified key roles of ty…
View article: RELMα and Pulmonary Vascular Remodeling: a Multi-Strain Murine Model of Antigen and Urban Ambient PM Co-Exposure
RELMα and Pulmonary Vascular Remodeling: a Multi-Strain Murine Model of Antigen and Urban Ambient PM Co-Exposure Open
Pulmonary hypertension (PH) has a high mortality, and few treatment options. Adaptive immune mediators of PH in mice challenged with antigen/particulate matter (antigen/PM) has been the focus of our prior work. We identified key roles of t…
View article: Nucleoside/nucleotide reverse transcriptase inhibitor sparing regimen with once daily integrase inhibitor plus boosted darunavir is non-inferior to standard of care in virologically-suppressed children and adolescents living with HIV – Week 48 results of the randomised SMILE Penta-17-ANRS 152 clinical trial
Nucleoside/nucleotide reverse transcriptase inhibitor sparing regimen with once daily integrase inhibitor plus boosted darunavir is non-inferior to standard of care in virologically-suppressed children and adolescents living with HIV – Week 48 results of the randomised SMILE Penta-17-ANRS 152 clinical trial Open
Fondazione Penta Onlus, Gilead, Janssen, INSERM/ANRS and UK MRC. ViiV-Healthcare provided Dolutegravir.
View article: 282 Food Intake REstriction for Health OUtcome Support and Education (FIREHOUSE): a Proof of Concept Randomized Clinical Trial
282 Food Intake REstriction for Health OUtcome Support and Education (FIREHOUSE): a Proof of Concept Randomized Clinical Trial Open
OBJECTIVES/GOALS: Particulate matter (PM) and metabolic syndrome (MetSyn) increase risk of World Trade Center-Lung Injury (WTC-LI). Mediterranean-type diets have also been found to improve lung function. Fire Department of New York 1st-res…
View article: Severe Acute Respiratory Syndrome and Particulate Matter Exposure: A Systematic Review
Severe Acute Respiratory Syndrome and Particulate Matter Exposure: A Systematic Review Open
Background: Particulate matter (PM) exposure is responsible for seven million deaths annually and has been implicated in the pathogenesis of respiratory infections such as severe acute respiratory syndrome (SARS). Understanding modifiable …
View article: Noninvasive, MultiOmic, and Multicompartmental Biomarkers of Reflux Disease: A Systematic Review
Noninvasive, MultiOmic, and Multicompartmental Biomarkers of Reflux Disease: A Systematic Review Open
Prior studies identified significant multiOmic, multicompartmental noninvasive biomarker risks for GERD and BE. However, studies have a high risk of bias and the reliability and accuracy of the biomarkers identified are greatly limited, wh…
View article: Non-Invasive, MultiOmic and MultiCompartmental Biomarkers of Reflux Disease: A Systematic Review
Non-Invasive, MultiOmic and MultiCompartmental Biomarkers of Reflux Disease: A Systematic Review Open
Background and Aims Gastroesophageal reflux disease (GERD) is a prevalent GI disorder which may complicate conditions such as obstructive airways disease (OAD). Our group has identified predictive biomarkers of GERD in particulate exposed …
View article: Dynamic Metabolic Risk Profiling of World Trade Center Lung Disease: A Longitudinal Cohort Study
Dynamic Metabolic Risk Profiling of World Trade Center Lung Disease: A Longitudinal Cohort Study Open
Rationale: Metabolic syndrome (MetSyn) increases the risk of World Trade Center (WTC) lung injury (LI). However, the temporal relationship of MetSyn, exposure intensity, and lung dysfunction is not well understood. Objective: To model the …
View article: PEDF, a pleiotropic WTC-LI biomarker: Machine learning biomarker identification and validation
PEDF, a pleiotropic WTC-LI biomarker: Machine learning biomarker identification and validation Open
Biomarkers predict World Trade Center-Lung Injury (WTC-LI); however, there remains unaddressed multicollinearity in our serum cytokines, chemokines, and high-throughput platform datasets used to phenotype WTC-disease. To address this conce…
View article: Exogenous RAGE Inhibitor Attenuates Particulate Matter Induced Airway Hyperreactivity
Exogenous RAGE Inhibitor Attenuates Particulate Matter Induced Airway Hyperreactivity Open
RATIONALE Metabolic Syndrome (MetSyn), is a cardiovascular disease risk.MetSyn phenotypic characteristics are predictors of World Trade Center-Lung Injury (WTC-LI) and airway hyperreactivity (AHR) in FDNY WTCparticulate matter (WTC-PM) exp…
View article: COVID-19 Myocarditis
COVID-19 Myocarditis Open
Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), emerged in Wuhan, China, and rapidly led to a global pandemic that affected 213 countries, more than 5.8 million cases, and 360,00…