Anna C. Phillips
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View article: Ketotic Hypoglycaemia Following Sleeve Gastrectomy
Ketotic Hypoglycaemia Following Sleeve Gastrectomy Open
Post‐bariatric surgery hypoglycaemia is typically mediated by hyperinsulinaemia, although the exact mechanisms are incompletely understood. Two cases of non‐insulin mediated, ketotic hypoglycaemia following sleeve gastrectomy are presented…
View article: The risk of recurrence of acute fatty liver of pregnancy – a review of the current literature
The risk of recurrence of acute fatty liver of pregnancy – a review of the current literature Open
Acute fatty liver of pregnancy is associated with significant maternal and fetal morbidity and mortality. Defects in fatty acid metabolism appear to play a role in pathogenesis, and several pathogenic variants leading to enzyme deficiencie…
View article: O069 At home lighting intervention as an adjunct to antidepressant treatment: A pilot study
O069 At home lighting intervention as an adjunct to antidepressant treatment: A pilot study Open
Evening light exposure is disruptive to sleep and circadian rhythms. This disruption may be amplified for people taking Selective-Serotonin Reuptake Inhibitors (SSRIs), as SSRIs increase sensitivity to the non-visual effects of light. Mini…
View article: Gastric emptying during and following resolution of moderate diabetic ketoacidosis in type 1 diabetes: a case series
Gastric emptying during and following resolution of moderate diabetic ketoacidosis in type 1 diabetes: a case series Open
Introduction To use the ‘gold standard’ technique of scintigraphy to quantify gastric emptying (GE) as soon as practicable during an admission with diabetic ketoacidosis (DKA) and following its resolution at least 7 days later. Research de…
View article: Bi-allelic loss-of-function OBSCN variants predispose individuals to severe recurrent rhabdomyolysis
Bi-allelic loss-of-function OBSCN variants predispose individuals to severe recurrent rhabdomyolysis Open
Rhabdomyolysis is the acute breakdown of skeletal myofibres in response to an initiating factor, most commonly toxins and over exertion. A variety of genetic disorders predispose to rhabdomyolysis through different pathogenic mechanisms, p…
View article: Biallelic loss-of-function <i>OBSCN</i> variants predispose individuals to severe, recurrent rhabdomyolysis
Biallelic loss-of-function <i>OBSCN</i> variants predispose individuals to severe, recurrent rhabdomyolysis Open
Rhabdomyolysis is the acute breakdown of skeletal myofibres in response to an initiating factor, most commonly toxins and over exertion. A variety of genetic disorders predispose to rhabdomyolysis through different pathogenic mechanisms, p…
View article: Effects of sustained treatment with lixisenatide on gastric emptying and postprandial glucose metabolism in type 2 diabetes: a randomized controlled trial
Effects of sustained treatment with lixisenatide on gastric emptying and postprandial glucose metabolism in type 2 diabetes: a randomized controlled trial Open
Objective Slowing of gastric emptying by GLP-1 exhibits tachyphylaxis with continuous exposure. We therefore aimed to establish whether prolonged use of a “short-acting” GLP-1 receptor agonist (GLP-1RA), lixisenatide, achieves susta…
View article: Effects of sustained treatment with lixisenatide on gastric emptying and postprandial glucose metabolism in type 2 diabetes: a randomized controlled trial
Effects of sustained treatment with lixisenatide on gastric emptying and postprandial glucose metabolism in type 2 diabetes: a randomized controlled trial Open
Objective Slowing of gastric emptying by GLP-1 exhibits tachyphylaxis with continuous exposure. We therefore aimed to establish whether prolonged use of a “short-acting” GLP-1 receptor agonist (GLP-1RA), lixisenatide, achieves susta…
View article: Autonomic function, postprandial hypotension and falls in older adults at one year after critical illness
Autonomic function, postprandial hypotension and falls in older adults at one year after critical illness Open
View article: The relationship between plasma GIP and GLP-1 levels in individuals with normal and impaired glucose tolerance
The relationship between plasma GIP and GLP-1 levels in individuals with normal and impaired glucose tolerance Open
View article: Author response for "Exenatide once weekly slows gastric emptying of solids and liquids in healthy, overweight, subjects under steady‐state concentrations"
Author response for "Exenatide once weekly slows gastric emptying of solids and liquids in healthy, overweight, subjects under steady‐state concentrations" Open
View article: The Effects of a Whey Protein and Guar Gum-Containing Preload on Gastric Emptying, Glycaemia, Small Intestinal Absorption and Blood Pressure in Healthy Older Subjects
The Effects of a Whey Protein and Guar Gum-Containing Preload on Gastric Emptying, Glycaemia, Small Intestinal Absorption and Blood Pressure in Healthy Older Subjects Open
A whey protein/guar gum preload reduces postprandial glycaemia in type 2 diabetes through slowing gastric emptying. However, gastric emptying has previously been assessed using a stable isotope breath test technique, which cannot discrimin…
View article: A randomized, crossover study of the acute effects of acarbose and gastric distension, alone and combined, on postprandial blood pressure in healthy older adults
A randomized, crossover study of the acute effects of acarbose and gastric distension, alone and combined, on postprandial blood pressure in healthy older adults Open
View article: Longitudinal Changes in Fasting and Glucose-Stimulated GLP-1 and GIP in Healthy Older Subjects
Longitudinal Changes in Fasting and Glucose-Stimulated GLP-1 and GIP in Healthy Older Subjects Open
Context It is not known whether glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) levels correlate within individuals, nor whether levels change with age. Previous studies have all been cross-sectional …
View article: Acute Effects of Nutritive and Non-Nutritive Sweeteners on Postprandial Blood Pressure
Acute Effects of Nutritive and Non-Nutritive Sweeteners on Postprandial Blood Pressure Open
Postprandial hypotension (PPH) is under-recognised, but common, particularly in the elderly, and is of clear clinical importance due to both the independent association between PPH and an increase in mortality and lack of effective managem…
View article: MON-457 One in Five Patients Develop Multiple Hormone Deficiencies Following Radiotherapy for Acromegaly or Cushing's Disease
MON-457 One in Five Patients Develop Multiple Hormone Deficiencies Following Radiotherapy for Acromegaly or Cushing's Disease Open
Aim: To characterise the use of radiotherapy (RTx) for corticotropinomas and somatotropinomas and the long-term clinical outcome for these patients. Methods: All patients with corticotropinomas (CD) and somatotropinomas (AC) who were treat…
View article: MULTIMORBIDITY INFLUENCES SUPPORT FOR PHYSICAL ACTIVITY AMONG ADULTS WITH OSTEOARTHRITIS AND THEIR PARTNERS
MULTIMORBIDITY INFLUENCES SUPPORT FOR PHYSICAL ACTIVITY AMONG ADULTS WITH OSTEOARTHRITIS AND THEIR PARTNERS Open
Background: Physical activity (PA) reduces pain and disability in people with osteoarthritis (PWOA); however, approximately 47% PWOA are insufficiently active. Multiple health problems (“multimorbidity) is a concerning issue among PWOA and…
View article: Nicotine preloading for smoking cessation: the Preloading RCT
Nicotine preloading for smoking cessation: the Preloading RCT Open
Background Nicotine preloading means using nicotine replacement therapy prior to a quit date while smoking normally. The aim is to reduce the drive to smoke, thereby reducing cravings for smoking after quit day, which are the main cause of…
View article: FO026TIME-TREND COMPARATIVE ASSOCIATIONS OF MUSCLE STRENGTH AND MASS, CARDIORESPIRATORY FITNESS, AND PHYSICAL ACTIVITY LEVEL WITH 6-YEAR CLINICAL OUTCOMES AND QUALITY OF LIFE IN KIDNEY TRANSPLANTATION
FO026TIME-TREND COMPARATIVE ASSOCIATIONS OF MUSCLE STRENGTH AND MASS, CARDIORESPIRATORY FITNESS, AND PHYSICAL ACTIVITY LEVEL WITH 6-YEAR CLINICAL OUTCOMES AND QUALITY OF LIFE IN KIDNEY TRANSPLANTATION Open
View article: Long-term mortality of critically ill patients with diabetes who survive admission to the intensive care unit
Long-term mortality of critically ill patients with diabetes who survive admission to the intensive care unit Open
Our study indicates that crude mortality for ICU survivors with pre-existing diabetes is considerable after hospital discharge, and the risk of mortality is greater than for survivors without diabetes.
View article: The Associations of Endotoxemia With Systemic Inflammation, Endothelial Activation, and Cardiovascular Outcome in Kidney Transplantation
The Associations of Endotoxemia With Systemic Inflammation, Endothelial Activation, and Cardiovascular Outcome in Kidney Transplantation Open
View article: Nicotine delivery to users from cigarettes and from different types of e-cigarettes
Nicotine delivery to users from cigarettes and from different types of e-cigarettes Open
EC brands we tested do not deliver nicotine as efficiently as cigarettes, but newer EC products deliver nicotine more efficiently than cig-a-like brands. Moderate variations in nicotine content of e-liquid have little effect on nicotine de…
View article: Nutrient stimulation of mesenteric blood flow - implications for older critically ill patients
Nutrient stimulation of mesenteric blood flow - implications for older critically ill patients Open
Nutrient ingestion induces a substantial increase in mesenteric blood flow. In older persons (aged ≥ 65 years), particularly those with chronic medical conditions, the cardiovascular compensatory response may be inadequate to maintain syst…
View article: Stress Induced Hyperglycemia and the Subsequent Risk of Type 2 Diabetes in Survivors of Critical Illness
Stress Induced Hyperglycemia and the Subsequent Risk of Type 2 Diabetes in Survivors of Critical Illness Open
Stress induced hyperglycemia identifies patients at subsequent risk of incident diabetes.
View article: Survivors of intensive care with type 2 diabetes and the effect of shared care follow-up clinics: study protocol for the SWEET-AS randomised controlled feasibility study
Survivors of intensive care with type 2 diabetes and the effect of shared care follow-up clinics: study protocol for the SWEET-AS randomised controlled feasibility study Open
View article: Stress hyperglycaemia in critically ill patients and the subsequent risk of diabetes: a systematic review and meta-analysis
Stress hyperglycaemia in critically ill patients and the subsequent risk of diabetes: a systematic review and meta-analysis Open
Stress hyperglycaemia during ICU admission is associated with increased risk of incident diabetes. The strength of this association remains uncertain because of statistical and clinical heterogeneity among the included studies.
View article: Corrigendum to ‘Morning vaccination enhances antibody response over afternoon vaccination: A cluster-randomised trial’ [Vaccine 34 (2016) 2679–2685]
Corrigendum to ‘Morning vaccination enhances antibody response over afternoon vaccination: A cluster-randomised trial’ [Vaccine 34 (2016) 2679–2685] Open
View article: Cardiovascular reactivity patterns and pathways to hypertension: a multivariate cluster analysis
Cardiovascular reactivity patterns and pathways to hypertension: a multivariate cluster analysis Open
View article: MO066ESTABLISHING THE RELATIONSHIP OF MUSCLE STRENGTH AND MUSCLE MASS WITH 5-YEAR CLINICAL OUTCOMES IN KIDNEY TRANSPLANTATION
MO066ESTABLISHING THE RELATIONSHIP OF MUSCLE STRENGTH AND MUSCLE MASS WITH 5-YEAR CLINICAL OUTCOMES IN KIDNEY TRANSPLANTATION Open
View article: Morning vaccination enhances antibody response over afternoon vaccination: A cluster-randomised trial
Morning vaccination enhances antibody response over afternoon vaccination: A cluster-randomised trial Open