Anna Ralser
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View article: RNF43 is a gatekeeper for colitis-associated cancer
RNF43 is a gatekeeper for colitis-associated cancer Open
SUMMARY Somatic mutations in the tumor suppressor Ring finger protein 43 ( RNF43 ) were frequently found in colitis-associated cancer (CAC) and related to the duration of chronic inflammation, but their significance in inflammation and inf…
View article: Gut virome profiling identifies an association between temperate phages and colorectal cancer promoted by <i>Helicobacter pylori</i> infection
Gut virome profiling identifies an association between temperate phages and colorectal cancer promoted by <i>Helicobacter pylori</i> infection Open
Colorectal cancer (CRC) is one of the most commonly diagnosed cancers worldwide. While a close correlation between chronic Helicobacter pylori infection and CRC has been reported, the role of the virome has been overlooked. Here, we infect…
View article: <i>Helicobacter pylori</i> promotes colorectal carcinogenesis by deregulating intestinal immunity and inducing a mucus-degrading microbiota signature
<i>Helicobacter pylori</i> promotes colorectal carcinogenesis by deregulating intestinal immunity and inducing a mucus-degrading microbiota signature Open
Objective Helicobacter pylori infection is the most prevalent bacterial infection worldwide. Besides being the most important risk factor for gastric cancer development, epidemiological data show that infected individuals harbour a nearly …
View article: Altered virome structrue and function characterization in <i>Helicobacter pylori</i>-driven colorectal carcinogenesis and <i>H. pylori</i> eradication
Altered virome structrue and function characterization in <i>Helicobacter pylori</i>-driven colorectal carcinogenesis and <i>H. pylori</i> eradication Open
The understanding of gut virome and its role in Helicobacter pylori -driven colorectal cancer (CRC), as well as the long-term impact of H. pylori eradication via antibiotic treatment on it could contribute to better understanding the mecha…
View article: <i>Helicobacter pylori</i> promotes colorectal carcinogenesis by deregulating intestinal immunity and inducing a mucus-degrading microbiota signature
<i>Helicobacter pylori</i> promotes colorectal carcinogenesis by deregulating intestinal immunity and inducing a mucus-degrading microbiota signature Open
OBJECTIVE H. pylori infection is the most prevalent bacterial infection worldwide. Besides being the most important risk factor for gastric cancer development, epidemiological data show that infected individuals harbor a nearly two-fold in…
View article: Engagement of CEACAM1 by Helicobacter pylori HopQ Is Important for the Activation of Non-Canonical NF-κB in Gastric Epithelial Cells
Engagement of CEACAM1 by Helicobacter pylori HopQ Is Important for the Activation of Non-Canonical NF-κB in Gastric Epithelial Cells Open
The gastric pathogen Helicobacter pylori infects half of the world’s population and is a major risk factor for gastric cancer development. In order to attach to human gastric epithelial cells and inject the oncoprotein CagA into host cells…