Anna C. Seale
YOU?
Author Swipe
View article: Effect of maternal infection on stillbirths and early neonatal deaths: nested case-control studies in pregnancy cohorts in East Africa
Effect of maternal infection on stillbirths and early neonatal deaths: nested case-control studies in pregnancy cohorts in East Africa Open
Summary Background Reducing perinatal deaths is a priority, but data on maternal infectious causes are sparse in low- and middle-income countries where the burden is highest. We aimed to describe maternal infections at delivery and their a…
View article: Modelling Semi-Random Human Mixing: A Modified Force of Infection in Population-level Epidemic Modelling
Modelling Semi-Random Human Mixing: A Modified Force of Infection in Population-level Epidemic Modelling Open
Mathematical modelling can help inform public health policies; however, the assumptions about mixing impact results. Classical models typically assume everyone has an equal likelihood of interacting with everyone else, whereas in reality, …
View article: Understanding factors influencing the implementation and uptake of less-established adult vaccination programmes: A meta-ethnography of COVID-19 vaccination in Nigeria
Understanding factors influencing the implementation and uptake of less-established adult vaccination programmes: A meta-ethnography of COVID-19 vaccination in Nigeria Open
Before COVID-19, a few studies examined adult vaccination programmes for disease outbreaks in Nigeria. Recent studies explored vaccine uptake factors, but few examined implementation. We aimed to understand factors influencing the implemen…
View article: How Can We Accelerate Maternal Vaccination Globally?
How Can We Accelerate Maternal Vaccination Globally? Open
New maternal vaccines could reduce infant deaths at and after birth, especially in low- and middle-income countries. Work is underway to prepare for new maternal vaccines globally, and the Maternal Immunization Readiness Network for Africa…
View article: Genomic epidemiology and longitudinal sampling of ward wastewater environments and patients reveals complexity of the transmission dynamics of <i>bla</i> KPC-carbapenemase-producing Enterobacterales in a hospital setting
Genomic epidemiology and longitudinal sampling of ward wastewater environments and patients reveals complexity of the transmission dynamics of <i>bla</i> KPC-carbapenemase-producing Enterobacterales in a hospital setting Open
Background Healthcare-associated wastewater and asymptomatic patient reservoirs colonized by carbapenemase-producing Enterobacterales (CPE) contribute to nosocomial CPE dissemination, but the characteristics and dynamics of this remain unc…
View article: Burden, causes, and risk factors of perinatal mortality in Eastern Africa: a protocol for systematic review and meta-analysis
Burden, causes, and risk factors of perinatal mortality in Eastern Africa: a protocol for systematic review and meta-analysis Open
Background Although global mortality rates in children under 5 years have decreased substantially in the last 30 years, there remain around 2.6 million stillbirths and 2.9 million neonatal deaths each year. The majority of these deaths occ…
View article: Cycle Threshold Values as Indication of Increasing SARS-CoV-2 New Variants, England, 2020–2022
Cycle Threshold Values as Indication of Increasing SARS-CoV-2 New Variants, England, 2020–2022 Open
Early detection of increased infections or new variants of SARS-CoV-2 is critical for public health response. To determine whether cycle threshold (Ct) data from PCR tests for SARS-CoV-2 could serve as an early indicator of epidemic growth…
View article: Early-onset group B streptococcal disease in African countries and maternal vaccination strategies
Early-onset group B streptococcal disease in African countries and maternal vaccination strategies Open
Invasive group B streptococcal (GBS) disease is the commonest perinatally-acquired bacterial infection in newborns; the burden is higher in African countries where intrapartum antibiotic prophylaxis strategies are not feasible. In sub-Saha…
View article: Replacement dynamics and the pathogenesis of the Alpha, Delta and Omicron variants of SARS-CoV-2
Replacement dynamics and the pathogenesis of the Alpha, Delta and Omicron variants of SARS-CoV-2 Open
New SARS-CoV-2 variants causing COVID-19 are a major risk to public health worldwide due to the potential for phenotypic change and increases in pathogenicity, transmissibility and/or vaccine escape. Recognising signatures of new variants …
View article: Detection of pathogens associated with early-onset neonatal sepsis in cord blood at birth using quantitative PCR
Detection of pathogens associated with early-onset neonatal sepsis in cord blood at birth using quantitative PCR Open
Background: Early onset neonatal sepsis (EONS) typically begins prior to, during or soon after birth and may be rapidly fatal. There is paucity of data on the aetiology of EONS in sub-Saharan Africa due to limited diagnostic capacity in t…
View article: Burden, causes, and risk factors of perinatal mortality in Eastern Africa: a protocol for systematic review and meta-analysis
Burden, causes, and risk factors of perinatal mortality in Eastern Africa: a protocol for systematic review and meta-analysis Open
Background: Although global mortality rates in children under 5 years have decreased substantially in the last 30 years, there remain around 2.6 million stillbirths and 2.9 million neonatal deaths each year. The majority of these deaths o…
View article: Standardization of Epidemiological Surveillance of Group A Streptococcal Cellulitis
Standardization of Epidemiological Surveillance of Group A Streptococcal Cellulitis Open
Cellulitis is an acute bacterial infection of the dermis and subcutaneous tissue usually found complicating a wound, ulcer, or dermatosis. This article provides guidelines for the surveillance of cellulitis. The primary objectives of cellu…
View article: Standardization of Epidemiological Surveillance of Acute Poststreptococcal Glomerulonephritis
Standardization of Epidemiological Surveillance of Acute Poststreptococcal Glomerulonephritis Open
Acute poststreptococcal glomerulonephritis (APSGN) is an immune complex-induced glomerulonephritis that develops as a sequela of streptococcal infections. This article provides guidelines for the surveillance of APSGN due to group A Strept…
View article: Standardization of Epidemiological Surveillance of Group A Streptococcal Pharyngitis
Standardization of Epidemiological Surveillance of Group A Streptococcal Pharyngitis Open
Pharyngitis, more commonly known as sore throat, is caused by viral and/or bacterial infections. Group A Streptococcus (Strep A) is the most common bacterial cause of pharyngitis. Strep A pharyngitis is an acute, self-limiting disease but …
View article: Standardization of Epidemiological Surveillance of Group A Streptococcal Impetigo
Standardization of Epidemiological Surveillance of Group A Streptococcal Impetigo Open
Impetigo is a highly contagious bacterial infection of the superficial layer of skin. Impetigo is caused by group A Streptococcus (Strep A) and Staphylococcus aureus, alone or in combination, with the former predominating in many tropical …
View article: Impact of Intermittent Presumptive Treatment for Malaria in Pregnancy on Hospital Birth Outcomes on the Kenyan Coast
Impact of Intermittent Presumptive Treatment for Malaria in Pregnancy on Hospital Birth Outcomes on the Kenyan Coast Open
Background Intermittent preventive treatment (IPTp) for pregnant women with sulfadoxine–pyrimethamine (SP) is widely implemented for the prevention of malaria in pregnancy and adverse birth outcomes. The efficacy of SP is declining, and th…
View article: Detection of pathogens associated with early-onset neonatal sepsis in cord blood at birth using quantitative PCR
Detection of pathogens associated with early-onset neonatal sepsis in cord blood at birth using quantitative PCR Open
Background: Early onset neonatal sepsis (EONS) typically begins prior to, during or soon after birth and may be rapidly fatal. There is paucity of data on the aetiology of EONS in sub-Saharan Africa due to limited diagnostic capacity in th…
View article: Replication Data for: The impact of intermittent presumptive treatment for malaria in pregnancy on hospital birth outcomes on the Kenyan coast
Replication Data for: The impact of intermittent presumptive treatment for malaria in pregnancy on hospital birth outcomes on the Kenyan coast Open
This is a replication dataset for the submitted manuscript titled: "The impact of intermittent presumptive treatment for malaria in pregnancy on hospital birth outcomes on the Kenyan coast." These data comprise data obtained from the mater…
View article: The Impact of Interventions to Prevent Neonatal Healthcare-associated Infections in Low- and Middle-income Countries: A Systematic Review
The Impact of Interventions to Prevent Neonatal Healthcare-associated Infections in Low- and Middle-income Countries: A Systematic Review Open
BACKGROUND Clinically suspected and laboratory-confirmed bloodstream infections are frequent causes of morbidity and mortality during neonatal care. The most effective infection prevention and control interventions for neonates in low- and…
View article: Setting up child health and mortality prevention surveillance in Ethiopia
Setting up child health and mortality prevention surveillance in Ethiopia Open
Background: Mortality rates for children under five years of age, and stillbirth risks, remain high in parts of sub-Saharan Africa and South Asia. The Child Health and Mortality Prevention Surveillance (CHAMPS) network aims to ascertain ca…
View article: Detection of pathogens associated with early-onset neonatal sepsis in cord blood at birth using quantitative PCR
Detection of pathogens associated with early-onset neonatal sepsis in cord blood at birth using quantitative PCR Open
Background: Early onset neonatal sepsis (EONS) typically begins prior to, during or soon after birth and may be rapidly fatal. There is paucity of data on the aetiology of EONS in sub-Saharan Africa due to limited diagnostic capacity in th…
View article: Replication Data for: Detection of pathogens associated with early-onset neonatal sepsis in cord blood at birth using quantitative PCR
Replication Data for: Detection of pathogens associated with early-onset neonatal sepsis in cord blood at birth using quantitative PCR Open
This is a replication dataset for the manuscript titled:"Detection of pathogens associated with early-onset neonatal sepsis in cord blood at birth using quantitative PCR" submitted to Welcome Open Research journal. There is paucity of data…
View article: A snapshot of the practicality and barriers to COVID-19 interventions: Public health and healthcare workers’ perceptions in high and low- and middle-income countries
A snapshot of the practicality and barriers to COVID-19 interventions: Public health and healthcare workers’ perceptions in high and low- and middle-income countries Open
Background In response to the COVID-19 pandemic, governments have implemented a range of non-pharmaceutical interventions (NPIs) and pharmaceutical interventions (PIs) to reduce transmission and minimise morbidity and mortality, whilst mai…
View article: Setting up child health and mortality prevention surveillance in Ethiopia
Setting up child health and mortality prevention surveillance in Ethiopia Open
Background: Mortality rates for children under five years of age, and stillbirth risks, remain high in parts of sub-Saharan Africa and South Asia. The Child Health and Mortality Prevention Surveillance (CHAMPS) network aims to ascertain ca…